Major histocompatibility complex class II alleles and the course and outcome of MS: A population-based study

Neurology

Volumn 51, Issue 3, 1998, Pages 742-747

  Weinshenker, Brian G ^a   Santrach, P ^a   Bissonet, A S ^a   McDonnell, S K ^a   Schaid, D ^a   Moore, S B ^a   Rodriguez, M ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HLA DQ ANTIGEN; HLA DR ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ADULT; ALLELE; ARTICLE; AUTOIMMUNITY; DISEASE COURSE; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENE MAPPING; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; HUMAN; MAJOR CLINICAL STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MULTIPLE SCLEROSIS; OUTCOMES RESEARCH; POPULATION RESEARCH; PRIORITY JOURNAL;

EID: 0031783392     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.51.3.742     Document Type: Article

References (34)

1. Weinshenker BG. The natural history of multiple sclerosis. Neurol Clin 1995;13:119-146.
2. Wicker LS, Todd JA, Peterson LB. Genetic control of autoimmune diabetes in the NOD mouse. Annu Rev Immunol 1995; 13:179-200.
3. Garchon HJ. Non-MHC-linked genes in autoimmune diseases. Curr Opin Immunol 1993;5:894-899.
4. Shultz LD. Immunological mutants of the mouse. Am J Anatomy 1991;191:303-311.
5. Benoist C, Mathis D. Transgenes and knock-outs in autoimmunity. Curr Opin Immunol 1993;5:900-902.
6. Weyand CM, Hicok KC, Conn DL, Goronzy JJ. The influence of HLA-DRB1 genes on disease severity in rheumatoid arthritis. Ann Intern Med 1992;117:801-806.
7. Olerup O, Hillert J. HLA class II-associated genetic susceptibility in multiple sclerosis: a critical evaluation. Tissue Antigens 1991;38:1-15.
8. The Multiple Sclerosis Genetics Group. A complete genomic screen for multiple sclerosis underscores a role for the major histocompatibility complex. Nat Genet 1996;13:469-471.
9. Sawcer S, Jones H, Feakes R, et al. A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22. Nat Genet 1996;13:464-468.
10. Ebers GC, Kukay K, Bulman DE, et al. A full genome search in multiple sclerosis. Nat Genet 1996;13:472-476.
11. Rodriguez M, Siva A, Ward J, et al. Impairment, disability and handicap in multiple sclerosis: a population-based study in Olmsted County, Minnesota. Neurology 1994;44:28-33.
12. Weinshenker BG, Wingerchuk DM, Liu Q, Bissonet AS, Schaid DJ, Sommer SS. Genetic variation in the tumor necrosis factor alpha gene and the outcome of multiple sclerosis. Neurology 1997;49:378-385.
13. Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988;16:1215.
14. Noreen HJ, Davidson ML, McCullough J, Bach FH, Segall M. HLA class II typing by restriction fragment length polymorphism (RFLP) in unrelated bone marrow transplant patients. Transplant Proc 1989;21:2968-2970.
15. Park MS, Tonai R. Phenotype frequencies of the class II (DR, DQ) DNA alleles by the patterns of sequence-specific primer mixtures (SSPM) in four different populations and the probable haplotypes between DRB1 allele and DQB1 allele. In: Terasaki PI, Cecka JM, eds. Clinical transplants. Los Angeles: UCLA Tissue Typing Laboratory, 1992.
16. Payami H, Joe S, Farid NR, et al. Relative predispositional effects (RPEs) of marker alleles with disease: HLA-DR alleles and Graves disease. Am J Hum Genet 1989;45:541-546.
17. Raun NE, Fog T, Heltberg A, et al. Correlation of the course of MS and histocompatibility antigen. In: Bauer HJ, Poser S, Ritter G, eds. Progress in MS research. Berlin: Springer-Verlag, 1980:456-459.
18. Stendahl-Brodin L, Link H, Moller G, et al. Genetic basis of MS: HLA antigens, disease progression, and oligoclonal IgG in CSF. Acta Neurol Scand 1979;59:297-308.
19. Engell T, Raun NE, Thomsen M, et al. HLA and heterogeneity of MS. Neurology 1982;32:1043-1046.
20. Duquette P, Decary F, Pleines J, et al. Clinical subgroups of MS in relation to HLA: DR alleles as possible markers of disease progression. Can J Neurol Sci 1985;12:106-110.
21. Madigand M, Oger JJF, Fauchet R, et al. HLA profiles in MS suggest two forms of the disease and the existence of protective haplotypes. J Neurol Sci 1982;53:519-529.
22. Poser S, Ritter G, Bauer HJ, et al. HLA-antigens and the prognosis of multiple sclerosis. J Neurol 1981;225:219-221.
23. British and Dutch Multiple Sclerosis Azathioprine Trial Group. Histocompatibility antigens in MS patients participating in a multicentre trial of azathioprine. J Neurol Neurosurg Psychiatry 1988;51:412-415.
24. Runmarker B, Martinsson T, Wahlstrom J, Andersen O. HLA and prognosis in multiple sclerosis. J Neurol 1994;241: 385-390.
25. Francis DA, Thompson AJ, Brookes P, et al. Multiple sclerosis and HLA: is the susceptibility gene really HLA-DR or -DQ? Hum Immunol 1991;32:119-124.
26. Olerup O, Hillert J, Fredrikson S, et al. Primarily chronic progressive and relapsing-remitting multiple sclerosis: two immunogenetically distinct disease entities. Proc Natl Acad Sci USA 1989;86:7113-7117.
27. Thompson AJ, Kermode AG, Wicks D, et al. Major differences in the dynamics of primary and secondary progressive multiple sclerosis. Ann Neurol 1991;29:53-62.
28. Revesz T, Kidd D, Thompson AJ, Barnard RO, McDonald WI. A comparison of the pathology of primary and secondary progressive multiple sclerosis. Brain 1994;117:759-765.
29. O'Riordan JI, Gallagher HL, Thompson AJ, et al. Clinical, CSF and MRI findings in Devic's neuromyelitis optica. J Neurol Neurosurg Psychiatry 1996;60:382-387.
30. Hogancamp WE, Weinshenker BG. The spectrum of Devic's syndrome. Neurology 1996;46(suppl):A254. Abstract.
31. Kira J, Kanai T, Nishimura Y, et al. Western versus Asian types of multiple sclerosis: immunogenetically and clinically distinct disorders. Ann Neurol 1996;40:569-574.
32. Zanelli E, Gonzalez-Gay MA, David C. Could HLA-DRB1 be the protective locus in rheumatoid arthritis? Immunol Today 1995;16:274-278.
33. Nabozny GH, Baisch JM, Cheng S, et al. HLA-DQ8 transgenic mice are highly susceptible to collagen-induced arthritis: a novel model for human polyarthritis. J Exp Med 1996;183: 27-37.
34. Francis DA, Batchelor JR, McDonald WI, et al. Multiple sclerosis in north-east Scotland: an association with DQW1. Brain 1987;110:181-196.