-
1
-
-
0001146538
-
Kinetics of distribution of substances administered to the body
-
Teorell T: Kinetics of distribution of substances administered to the body. Arch Intern Pharmocodyn 1937;57:205-240.
-
(1937)
Arch Intern Pharmocodyn
, vol.57
, pp. 205-240
-
-
Teorell, T.1
-
2
-
-
0342437515
-
Enzyme-catalyzed processes of first-pass hepatic and intestinal drug extraction
-
Thummel KE, Kunze KL, Shen DD: Enzyme-catalyzed processes of first-pass hepatic and intestinal drug extraction. Adv Drug Del Rev 1997;27:99-127.
-
(1997)
Adv Drug Del Rev
, vol.27
, pp. 99-127
-
-
Thummel, K.E.1
Kunze, K.L.2
Shen, D.D.3
-
3
-
-
0036093847
-
The mucosa of the small intestine: How clinically relevant as an organ of drug metabolism?
-
Doherty M, Charman W: The mucosa of the small intestine: how clinically relevant as an organ of drug metabolism? Clin Phormacokinet 2002;41(4):235-253.
-
(2002)
Clin Phormacokinet
, vol.41
, Issue.4
, pp. 235-253
-
-
Doherty, M.1
Charman, W.2
-
4
-
-
0026605427
-
Enhancement of biological activity by conjugation reactions
-
Olson JA, Moon RC, Anders MW, Fenselau C, Shane B: Enhancement of biological activity by conjugation reactions. J Nutr 1992; 122(Suppl.):615-624.
-
(1992)
J Nutr
, vol.122
, Issue.SUPPL.
, pp. 615-624
-
-
Olson, J.A.1
Moon, R.C.2
Anders, M.W.3
Fenselau, C.4
Shane, B.5
-
5
-
-
0027312494
-
Factors and conditions affecting the glucuronidation of oxazepam
-
Sonne J: Factors and conditions affecting the glucuronidation of oxazepam. Pharmacol Toxicol 1993;73(Suppl. 1):1-23.
-
(1993)
Pharmacol Toxicol
, vol.73
, Issue.SUPPL. 1
, pp. 1-23
-
-
Sonne, J.1
-
6
-
-
0019163093
-
Isoprenaline conjugation: A "true first-pass effect" in the dog intestine
-
Ilett KF, Dollery CT, Davies DS: Isoprenaline conjugation: a "true first-pass effect" in the dog intestine. J Pharm Pharmocol 1980; 32(5):362.
-
(1980)
J Pharm Pharmocol
, vol.32
, Issue.5
, pp. 362
-
-
Ilett, K.F.1
Dollery, C.T.2
Davies, D.S.3
-
7
-
-
0019842582
-
Drug metabolism by the gastrointestine mucosa
-
Geroge CF: Drug metabolism by the gastrointestine mucosa. Clin Pharmacokinet 1981;6(4):259-274.
-
(1981)
Clin Pharmacokinet
, vol.6
, Issue.4
, pp. 259-274
-
-
Geroge, C.F.1
-
8
-
-
0034821939
-
Role of transport proteins in drug absorption, distribution and excretion
-
Ayrton A, Morgan P: Role of transport proteins in drug absorption, distribution and excretion. Xenobiotica 2001;31:469-497.
-
(2001)
Xenobiotica
, vol.31
, pp. 469-497
-
-
Ayrton, A.1
Morgan, P.2
-
9
-
-
0034724324
-
Functional polymorphisms of the human multidrugresistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
-
Hoffmeyer S, Burk O, von Richter O, Arnold HP, Rockmoller J, Johne A, et al: Functional polymorphisms of the human multidrugresistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc Nat Acad Sci USA 2000;97:3473-3478.
-
(2000)
Proc Nat Acad Sci USA
, vol.97
, pp. 3473-3478
-
-
Hoffmeyer, S.1
Burk, O.2
Von Richter, O.3
Arnold, H.P.4
Rockmoller, J.5
Johne, A.6
-
10
-
-
0031455482
-
The P-glycoprotein efflux pump: How does it transport drugs?
-
Sharom FJ: The P-glycoprotein efflux pump: how does it transport drugs? J Membr Biol 1997;160:161-175.
-
(1997)
J Membr Biol
, vol.160
, pp. 161-175
-
-
Sharom, F.J.1
-
11
-
-
0036000312
-
A mechanistic approach to understanding the factors affecting drug absorption: A review of fundamentals
-
Martinez M, Amidon G: A mechanistic approach to understanding the factors affecting drug absorption: a review of fundamentals. J Clin Pharmacol 2002;42:620-643.
-
(2002)
J Clin Pharmacol
, vol.42
, pp. 620-643
-
-
Martinez, M.1
Amidon, G.2
-
12
-
-
0031944723
-
Overlapping substrate specificities of cytochrome P450 3A and P-glycoprotein for a novel cysteine protease inhibitor
-
Zhang Y, Gan X, Lin ET, Benet LZ: Overlapping substrate specificities of cytochrome P450 3A and P-glycoprotein for a novel cysteine protease inhibitor. Drug Metab Dispos 1998;26(4):360-366.
-
(1998)
Drug Metab Dispos
, vol.26
, Issue.4
, pp. 360-366
-
-
Zhang, Y.1
Gan, X.2
Lin, E.T.3
Benet, L.Z.4
-
13
-
-
0030002504
-
Intestinal drug metabolism and antitransport processes: A potential paradigm shift in oral drug delivery
-
Benet LZ, Wu C-Y, Hebert MF, et al: Intestinal drug metabolism and antitransport processes: a potential paradigm shift in oral drug delivery. J Control Rel 1996;39:139-143.
-
(1996)
J Control Rel
, vol.39
, pp. 139-143
-
-
Benet, L.Z.1
Wu, C.-Y.2
Hebert, M.F.3
-
14
-
-
9044252313
-
CYP3A-like cytochrome P450-mediated metabolism and polarized efflux of cylosporin A in caco-2 cells: Interaction between the two biochemical barriers to intestinal transport
-
Gan LS, Mosely MA, Khosla B, et al: CYP3A-like cytochrome P450-mediated metabolism and polarized efflux of cylosporin A in caco-2 cells: interaction between the two biochemical barriers to intestinal transport. Drug Metab Dispos 1996;24:344-349.
-
(1996)
Drug Metab Dispos
, vol.24
, pp. 344-349
-
-
Gan, L.S.1
Mosely, M.A.2
Khosla, B.3
-
15
-
-
0342762062
-
The barrier function of CYP3A4 and P-glycoprotein in the small bowel
-
Watkins PB: The barrier function of CYP3A4 and P-glycoprotein in the small bowel. Adv Drug Del Rev 1997;27:161-170.
-
(1997)
Adv Drug Del Rev
, vol.27
, pp. 161-170
-
-
Watkins, P.B.1
-
16
-
-
0035478419
-
The drug efflux-metabolism alliance: Biochemical aspects
-
Benet LZ, Cummins CL: The drug efflux-metabolism alliance: biochemical aspects. Adv Drug Del Rev 2001;50:S3-S11.
-
(2001)
Adv Drug Del Rev
, vol.50
-
-
Benet, L.Z.1
Cummins, C.L.2
-
17
-
-
0343416856
-
Contributions of hepatic and intestinal metabolism and P-glycoprotein to cyclosporine and tacrolimus oral drug delivery
-
Hebert MF: Contributions of hepatic and intestinal metabolism and P-glycoprotein to cyclosporine and tacrolimus oral drug delivery. Adv Drug Del Rev 1997;27:201-214.
-
(1997)
Adv Drug Del Rev
, vol.27
, pp. 201-214
-
-
Hebert, M.F.1
-
18
-
-
0032750225
-
The multidrug resistance protein family
-
Borst P, Evers R, Lool M, et al: The multidrug resistance protein family. Biochim Biophys Acta 1999;1461:347-357.
-
(1999)
Biochim Biophys Acta
, vol.1461
, pp. 347-357
-
-
Borst, P.1
Evers, R.2
Lool, M.3
-
19
-
-
0036206904
-
The impact of efflux transporters in the brain on the development of drugs for CNS disorders
-
Taylor EM: The impact of efflux transporters in the brain on the development of drugs for CNS disorders. Clin Pharmacokinet 2002; 41(2):81-92.
-
(2002)
Clin Pharmacokinet
, vol.41
, Issue.2
, pp. 81-92
-
-
Taylor, E.M.1
-
20
-
-
0033569442
-
The proton-linked monocarboxylate transporter (MCT) family: Structure, function and regulation
-
Halestrap AP, Price NT: The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation. Biochem J 1999;343:281-299.
-
(1999)
Biochem J
, vol.343
, pp. 281-299
-
-
Halestrap, A.P.1
Price, N.T.2
-
21
-
-
0016155396
-
Appraisal of digoxin bioavailability and pharmacokinetics in relation to cardiac therapy
-
Wagner JG: Appraisal of digoxin bioavailability and pharmacokinetics in relation to cardiac therapy. Am Heart J 1974;88:133-138.
-
(1974)
Am Heart J
, vol.88
, pp. 133-138
-
-
Wagner, J.G.1
-
22
-
-
0017352663
-
Clinical pharmacokinetics of digoxin
-
Iialo E: Clinical pharmacokinetics of digoxin. Clin Pharmacokinet 1977;2:1-6.
-
(1977)
Clin Pharmacokinet
, vol.2
, pp. 1-6
-
-
Iialo, E.1
-
23
-
-
0345577839
-
-
Salamanca, Spain
-
Dunne A, Corrigan OI, Bottini PB, Geoghegan EJ: Proc. 2nd European Congress of Biopharmaceutics and Pharmacokinetics, vol. 1, Salamanca, Spain, 1984.
-
(1984)
Proc. 2nd European Congress of Biopharmaceutics and Pharmacokinetics
, vol.1
-
-
Dunne, A.1
Corrigan, O.I.2
Bottini, P.B.3
Geoghegan, E.J.4
-
24
-
-
0028275918
-
Development and evaluation of a monolithic floating dosage form for furosemide
-
Menton A, Ritschel WA, Sakr A: Development and evaluation of a monolithic floating dosage form for furosemide. J Pharm Sci 1994; 83:239-245.
-
(1994)
J Pharm Sci
, vol.83
, pp. 239-245
-
-
Menton, A.1
Ritschel, W.A.2
Sakr, A.3
-
25
-
-
0030457324
-
Prolonged-release hydroxypropyl methylcellulose matrix tablets of furosemide for administration to dogs
-
Smal J, Marvola M, Lijequist C, Happonen I: Prolonged-release hydroxypropyl methylcellulose matrix tablets of furosemide for administration to dogs. J Vet Pharmacol Ther 1996;19:482-487.
-
(1996)
J Vet Pharmacol Ther
, vol.19
, pp. 482-487
-
-
Smal, J.1
Marvola, M.2
Lijequist, C.3
Happonen, I.4
-
26
-
-
0031890348
-
Evaluation of oral mucoadhesive microspheres in man on the basis of the pharmacokinetics of furosemide and riboflavin, compounds with limited gastrointestinal absorption sites
-
Akiyama Y, Nagahara N, Nara E, Kitano M, Iwasa S, Yamamoto I, et al: Evaluation of oral mucoadhesive microspheres in man on the basis of the pharmacokinetics of furosemide and riboflavin, compounds with limited gastrointestinal absorption sites. J Pharm Pharmacol 1998;50:159-166.
-
(1998)
J Pharm Pharmacol
, vol.50
, pp. 159-166
-
-
Akiyama, Y.1
Nagahara, N.2
Nara, E.3
Kitano, M.4
Iwasa, S.5
Yamamoto, I.6
-
27
-
-
0035029435
-
Improvement in site-specific intestinal absorption of furosemide by Eudragit L100-55
-
Terao T, Matsuda K, Shouji H: Improvement in site-specific intestinal absorption of furosemide by Eudragit L100-55. J Pharm Pharmacol 2001;53:433-440.
-
(2001)
J Pharm Pharmacol
, vol.53
, pp. 433-440
-
-
Terao, T.1
Matsuda, K.2
Shouji, H.3
-
28
-
-
0030928205
-
Prediction of the plasma concentration profiles of orally administered drugs in rats on the basis of gastrointestinal transit kinetics and absorbability
-
Sawamoto T, Haruta S, Kurosaki Y, Higaki K, Kimura T: Prediction of the plasma concentration profiles of orally administered drugs in rats on the basis of gastrointestinal transit kinetics and absorbability. J Pharm Pharmacol 1997;49(4):450-457.
-
(1997)
J Pharm Pharmacol
, vol.49
, Issue.4
, pp. 450-457
-
-
Sawamoto, T.1
Haruta, S.2
Kurosaki, Y.3
Higaki, K.4
Kimura, T.5
-
29
-
-
0031680610
-
Absorption behavior of orally administered drugs in rats treated with propantheline
-
Haruta S, Iwasaki N, Ogawara KI, Higaki K, Kimura T: Absorption behavior of orally administered drugs in rats treated with propantheline. J Pharm Sci 1998;87(9):1081-1085.
-
(1998)
J Pharm Sci
, vol.87
, Issue.9
, pp. 1081-1085
-
-
Haruta, S.1
Iwasaki, N.2
Ogawara, K.I.3
Higaki, K.4
Kimura, T.5
-
31
-
-
0031797635
-
Effect of age on pharmacokinetics and pharmacodynamics in man
-
Klotz U: Effect of age on pharmacokinetics and pharmacodynamics in man. Int J Clin Pharmacol Ther 1998;36(11):581-585.
-
(1998)
Int J Clin Pharmacol Ther
, vol.36
, Issue.11
, pp. 581-585
-
-
Klotz, U.1
-
32
-
-
0024835315
-
Clinical pharmacokinetics in infants and children: A reappraisal
-
Kearns GL, Reed MD: Clinical pharmacokinetics in infants and children: a reappraisal. Clin Pharmacokinet 1989;17(Suppl. 1):29-67.
-
(1989)
Clin Pharmacokinet
, vol.17
, Issue.SUPPL. 1
, pp. 29-67
-
-
Kearns, G.L.1
Reed, M.D.2
-
33
-
-
0023217333
-
Effect of maturation on drug disposition in pediatric patients
-
Stewart C, Hampton EM: Effect of maturation on drug disposition in pediatric patients. Clin Pharm 1987;6:548-564.
-
(1987)
Clin Pharm
, vol.6
, pp. 548-564
-
-
Stewart, C.1
Hampton, E.M.2
-
34
-
-
0028559818
-
Pharmacokinetic considerations in the adolescent: Non-cytochrome P450 metabolic pathways
-
Capparelli EV: Pharmacokinetic considerations in the adolescent: non-cytochrome P450 metabolic pathways. J Adolescent Health 1994;15:641-647.
-
(1994)
J Adolescent Health
, vol.15
, pp. 641-647
-
-
Capparelli, E.V.1
-
35
-
-
0029818304
-
Pharmacokinetics and renal function in preterm infants
-
van den Anker JN: Pharmacokinetics and renal function in preterm infants. Acta Pediatr 1996;85:1393-1399.
-
(1996)
Acta Pediatr
, vol.85
, pp. 1393-1399
-
-
Van den Anker, J.N.1
-
37
-
-
0025731162
-
Gender-related differences in iron absorption by preadolescent children
-
Woodhead JC, Drulis JM, Nelson SE, Janghorbani M, Fomon SJ: Gender-related differences in iron absorption by preadolescent children. Pediatr Res 1991;29:435-439.
-
(1991)
Pediatr Res
, vol.29
, pp. 435-439
-
-
Woodhead, J.C.1
Drulis, J.M.2
Nelson, S.E.3
Janghorbani, M.4
Fomon, S.J.5
-
38
-
-
0025105234
-
High blood alcohol levels in women, the role of decreased gastric alcohol dehydrogenase activity and first-pass metabolism
-
Frezza M, di Padova C, Pozzato G, Terpin M, Baraona E, Lieber CS: High blood alcohol levels in women, the role of decreased gastric alcohol dehydrogenase activity and first-pass metabolism. N Engl J Med 1990;322:95-99.
-
(1990)
N Engl J Med
, vol.322
, pp. 95-99
-
-
Frezza, M.1
Di Padova, C.2
Pozzato, G.3
Terpin, M.4
Baraona, E.5
Lieber, C.S.6
-
39
-
-
0345577837
-
Effects of pregnancy on pharmacokinetics
-
Benet LZ, Massoud N, Gmabertoglio JG (eds.). New York: Raven
-
Parker WA: Effects of pregnancy on pharmacokinetics, in: Benet LZ, Massoud N, Gmabertoglio JG (eds.), Pharmacokinetic Basis for Drug Treatment. New York: Raven, 1984.
-
(1984)
Pharmacokinetic Basis for Drug Treatment
-
-
Parker, W.A.1
-
40
-
-
0033950015
-
Predictability of the effects of race or ethnicity on pharmacokinetics of drugs
-
Johnson JA: Predictability of the effects of race or ethnicity on pharmacokinetics of drugs. Int J Clin Pharmacol Ther 2000; 38(2):53-60.
-
(2000)
Int J Clin Pharmacol Ther
, vol.38
, Issue.2
, pp. 53-60
-
-
Johnson, J.A.1
-
41
-
-
0028948839
-
A theoretical basis for a biopharmaceutic drug classification: The correlation of in vitro drug product dissolution and in vivo bioavailability
-
Amidon GL, Lennernas H, Shah VP, Crison JR: A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability. Pharm Res 1995;12(3):413-420.
-
(1995)
Pharm Res
, vol.12
, Issue.3
, pp. 413-420
-
-
Amidon, G.L.1
Lennernas, H.2
Shah, V.P.3
Crison, J.R.4
-
44
-
-
0029933886
-
Clinical pharmacokinetics of metformin
-
Scheen AJ: Clinical pharmacokinetics of metformin. Clin Pharmacokinet 1996;30(5):359-371.
-
(1996)
Clin Pharmacokinet
, vol.30
, Issue.5
, pp. 359-371
-
-
Scheen, A.J.1
-
45
-
-
0034888569
-
In vitro-in vivo correlation (IVIVC) models for metformin after administration of modifiedrelease (MR) oral dosage forms to healthy human volunteers
-
Balan G, Timmins P, Greene DS, Marathe PH: In vitro-in vivo correlation (IVIVC) models for metformin after administration of modifiedrelease (MR) oral dosage forms to healthy human volunteers. J Pharm Sci 2001;90(8):1176-1185.
-
(2001)
J Pharm Sci
, vol.90
, Issue.8
, pp. 1176-1185
-
-
Balan, G.1
Timmins, P.2
Greene, D.S.3
Marathe, P.H.4
-
46
-
-
0020912649
-
An incremental method for the study of the absorption of drugs whose kinetics are described by a two-compartment model: Estimation of the microscopic rate constants
-
Gerardin A, Wantiez D, Jaouen A: An incremental method for the study of the absorption of drugs whose kinetics are described by a two-compartment model: estimation of the microscopic rate constants. J Pharmacokinet Biopharm 1983;11(4):401-425.
-
(1983)
J Pharmacokinet Biopharm
, vol.11
, Issue.4
, pp. 401-425
-
-
Gerardin, A.1
Wantiez, D.2
Jaouen, A.3
-
47
-
-
0017331381
-
Interpretation of plasma concentration-time curves after oral dosing
-
Ronfeld R, Benet LZ: Interpretation of plasma concentration-time curves after oral dosing. J Pharm Sci 1977;66(2):178-180.
-
(1977)
J Pharm Sci
, vol.66
, Issue.2
, pp. 178-180
-
-
Ronfeld, R.1
Benet, L.Z.2
-
48
-
-
0021985795
-
Assessment of drug absorption after oral administration
-
Chan KKH, Gibaldi M: Assessment of drug absorption after oral administration. J Pharm Sci 1985;74(4):388-393.
-
(1985)
J Pharm Sci
, vol.74
, Issue.4
, pp. 388-393
-
-
Chan, K.K.H.1
Gibaldi, M.2
-
49
-
-
0027364852
-
Anomalous parameter estimates in the onecompartment model with first-order absorption
-
Purves RD: Anomalous parameter estimates in the onecompartment model with first-order absorption. J Pharm Pharmacol 1993;45:934-936.
-
(1993)
J Pharm Pharmacol
, vol.45
, pp. 934-936
-
-
Purves, R.D.1
-
50
-
-
0021257079
-
Evaluation drug absorption after oral administration: Some problems and some solutions
-
Chan KKH, Gibaldi M: Evaluation drug absorption after oral administration: some problems and some solutions. Eur J Clin Pharmacol 1984;26:255-259.
-
(1984)
Eur J Clin Pharmacol
, vol.26
, pp. 255-259
-
-
Chan, K.K.H.1
Gibaldi, M.2
-
51
-
-
0022918334
-
Pharmacokinetics of oral cyclosporin A (Sandimmun) in healthy subjects
-
Grevel J, Nüesch E, Abisch E, Kutz K: Pharmacokinetics of oral cyclosporin A (Sandimmun) in healthy subjects. Eur J Clin Pharmacol 1986;31:211-216.
-
(1986)
Eur J Clin Pharmacol
, vol.31
, pp. 211-216
-
-
Grevel, J.1
Nüesch, E.2
Abisch, E.3
Kutz, K.4
-
52
-
-
0014781217
-
The simultaneous emptying and absorption of ethanol from the human stomach
-
Cooke AR: The simultaneous emptying and absorption of ethanol from the human stomach. Am J Dig Dis 1970;15:449-454.
-
(1970)
Am J Dig Dis
, vol.15
, pp. 449-454
-
-
Cooke, A.R.1
-
53
-
-
0015341717
-
Pharmacokinetic profile of sulfisoxazole following intravenous, intramuscular and oral administration to man
-
Kaplan SA, Weinfeld RE, Abruzzo CW, Lewis M: Pharmacokinetic profile of sulfisoxazole following intravenous, intramuscular and oral administration to man. J Pharm Sci 1972;61:773-778.
-
(1972)
J Pharm Sci
, vol.61
, pp. 773-778
-
-
Kaplan, S.A.1
Weinfeld, R.E.2
Abruzzo, C.W.3
Lewis, M.4
-
54
-
-
0016752864
-
Apparent absorption kinetics of micronized griseofulvin after its oral administration on single- and multiple-dose regimens to rats as a corn oil-in-water emulsion and aqueous suspension
-
Bates TR, Carrigan PJ: Apparent absorption kinetics of micronized griseofulvin after its oral administration on single- and multiple-dose regimens to rats as a corn oil-in-water emulsion and aqueous suspension. J Pharm Sci 1975;64(9):1475-1481.
-
(1975)
J Pharm Sci
, vol.64
, Issue.9
, pp. 1475-1481
-
-
Bates, T.R.1
Carrigan, P.J.2
-
55
-
-
0017668605
-
Pharmacokinetics of erythromycin on repetitive dosing
-
Colburn WA, Di Santo AR, Gibaldi M: Pharmacokinetics of erythromycin on repetitive dosing. J Clin Pharmacol 1977;17(10, Pt. 1):592-600.
-
(1977)
J Clin Pharmacol
, vol.17
, Issue.10 PART 1
, pp. 592-600
-
-
Colburn, W.A.1
Di Santo, A.R.2
Gibaldi, M.3
-
57
-
-
0024609165
-
The area function method for assessing the drug absorption rate in linear systems with zero-order input
-
Cheng H, Jusko WJ: The area function method for assessing the drug absorption rate in linear systems with zero-order input. Pharm Res 1989;6(2):133-139.
-
(1989)
Pharm Res
, vol.6
, Issue.2
, pp. 133-139
-
-
Cheng, H.1
Jusko, W.J.2
-
58
-
-
0025238675
-
Effects of variation in drug elimination on five methods for assessing zero-order drug absorption rates
-
Cheng H, Jusko WJ: Effects of variation in drug elimination on five methods for assessing zero-order drug absorption rates. Pharm Res 1990;7(1):76-79.
-
(1990)
Pharm Res
, vol.7
, Issue.1
, pp. 76-79
-
-
Cheng, H.1
Jusko, W.J.2
-
59
-
-
0019274427
-
The application of statistical moment theory to the evaluation of in vivo dissolution time and absorption time
-
Riegelman S, Collier P: The application of statistical moment theory to the evaluation of in vivo dissolution time and absorption time. J Pharmacokinet Biopharm 1980;8(5):509-534.
-
(1980)
J Pharmacokinet Biopharm
, vol.8
, Issue.5
, pp. 509-534
-
-
Riegelman, S.1
Collier, P.2
-
60
-
-
0030945947
-
A modified residual method to estimate the zero-order absorption rate constant in a one-compartment model
-
Liu X, Brouwer KLR, Pollack GM: A modified residual method to estimate the zero-order absorption rate constant in a one-compartment model. Biopharm Drug Dispos 1997;18(2):93-101.
-
(1997)
Biopharm Drug Dispos
, vol.18
, Issue.2
, pp. 93-101
-
-
Liu, X.1
Brouwer, K.L.R.2
Pollack, G.M.3
-
61
-
-
0034049920
-
Pharmacokinetic-pharmacodynamic modelling of the antipyretic effect of two oral formulations of ibuprofen
-
Troconiz IF, Armenteros S, Planelles MV, Benitez J, Calvo R, Dominguez R: Pharmacokinetic-pharmacodynamic modelling of the antipyretic effect of two oral formulations of ibuprofen. Clin Pharmacokinet 2000;38(6):505-518.
-
(2000)
Clin Pharmacokinet
, vol.38
, Issue.6
, pp. 505-518
-
-
Troconiz, I.F.1
Armenteros, S.2
Planelles, M.V.3
Benitez, J.4
Calvo, R.5
Dominguez, R.6
-
62
-
-
0023414508
-
Pharmacokinetics of lignocaine and bupivacaine in surgical patients following epidural administration: Simultaneous investigation of absorption and disposition kinetics using stable isotopes
-
Burm AG, Vermeulen NP, van Kleef JW, de Boer AG, Spierdijk J, Breimer DD: Pharmacokinetics of lignocaine and bupivacaine in surgical patients following epidural administration: simultaneous investigation of absorption and disposition kinetics using stable isotopes. Clin Pharmacokinet 1987;13(3):191-203.
-
(1987)
Clin Pharmacokinet
, vol.13
, Issue.3
, pp. 191-203
-
-
Burm, A.G.1
Vermeulen, N.P.2
Van Kleef, J.W.3
De Boer, A.G.4
Spierdijk, J.5
Breimer, D.D.6
-
63
-
-
0023779873
-
A pharmacokinetic model for percutaenous absorption of valproic acid and prediction of drug disposition
-
Ogiso T, Ito Y, Iwaki M, Atago H, Yamamoto Y: A pharmacokinetic model for percutaenous absorption of valproic acid and prediction of drug disposition. J Pharmacobiodyn 1988;11(6):444-452.
-
(1988)
J Pharmacobiodyn
, vol.11
, Issue.6
, pp. 444-452
-
-
Ogiso, T.1
Ito, Y.2
Iwaki, M.3
Atago, H.4
Yamamoto, Y.5
-
64
-
-
0034529336
-
Population PK and PK/PD modelling of microencapsulated octreotide acetate in healthy subjects
-
Zhou H, Chen TL, Marino M, Lau H, Miller T, Kalafsky G, et al: Population PK and PK/PD modelling of microencapsulated octreotide acetate in healthy subjects. Br J Clin Pharmacol 2000; 50(6):543-552.
-
(2000)
Br J Clin Pharmacol
, vol.50
, Issue.6
, pp. 543-552
-
-
Zhou, H.1
Chen, T.L.2
Marino, M.3
Lau, H.4
Miller, T.5
Kalafsky, G.6
-
66
-
-
0024917730
-
Pharmacokinetics of an oral sustained-release diltiazem preparation
-
Murata K, Yamahara H, Kobayashi M, Noda K, Samejima M: Pharmacokinetics of an oral sustained-release diltiazem preparation. J Pharm Sci 1989;78(11):960-963.
-
(1989)
J Pharm Sci
, vol.78
, Issue.11
, pp. 960-963
-
-
Murata, K.1
Yamahara, H.2
Kobayashi, M.3
Noda, K.4
Samejima, M.5
-
67
-
-
0023144406
-
Pharmacokinetic analysis of concentration data of drugs with irregular absorption profiles using multi-fraction absorption models
-
Murata K, Noda K, Kohno K, Samejima M: Pharmacokinetic analysis of concentration data of drugs with irregular absorption profiles using multi-fraction absorption models. J Pharm Sci 1987;76(2): 109-113.
-
(1987)
J Pharm Sci
, vol.76
, Issue.2
, pp. 109-113
-
-
Murata, K.1
Noda, K.2
Kohno, K.3
Samejima, M.4
-
68
-
-
0030477907
-
Pharmacokinetic analysis of the absorption characteristics of diclofenac sodium in man by use of a multi-segment absorption model
-
Mahmood I: Pharmacokinetic analysis of the absorption characteristics of diclofenac sodium in man by use of a multi-segment absorption model. J Pharm Pharmacol 1996;48:1260-1263.
-
(1996)
J Pharm Pharmacol
, vol.48
, pp. 1260-1263
-
-
Mahmood, I.1
-
69
-
-
0018830564
-
Pharmacokinetics and bioavailability of cimetidine in human
-
Veng-Pedersen P: Pharmacokinetics and bioavailability of cimetidine in human. J Pharm Sci 1980;75:394-398.
-
(1980)
J Pharm Sci
, vol.75
, pp. 394-398
-
-
Veng-Pedersen, P.1
-
70
-
-
0017660328
-
Absorption and metabolism of lanatoside C: II. Fate after oral administration
-
Aldous S, Thomas R: Absorption and metabolism of lanatoside C: II. Fate after oral administration. Clin Pharmacol Ther 1977; 21(6):647-658.
-
(1977)
Clin Pharmacol Ther
, vol.21
, Issue.6
, pp. 647-658
-
-
Aldous, S.1
Thomas, R.2
-
71
-
-
0019442351
-
Penicillamine kinetics in normal subjects
-
Bergstrom RF, Kay D, Harkcom TM, Wagner JG: Penicillamine kinetics in normal subjects. Clin Pharmacol Ther 1981;30(3):404-413.
-
(1981)
Clin Pharmacol Ther
, vol.30
, Issue.3
, pp. 404-413
-
-
Bergstrom, R.F.1
Kay, D.2
Harkcom, T.M.3
Wagner, J.G.4
-
72
-
-
0019351711
-
Pharmacokinetic analysis by linear system approach: I. Cimetidine bioavailability and second peak phenomenon
-
Veng Pedersen P: Pharmacokinetic analysis by linear system approach: I. Cimetidine bioavailability and second peak phenomenon. J Pharm Sci 1981;70:32-38.
-
(1981)
J Pharm Sci
, vol.70
, pp. 32-38
-
-
Veng Pedersen, P.1
-
73
-
-
0015928022
-
Value of plasma digoxin estimation
-
Beerman B: Value of plasma digoxin estimation. Lancet 1973;1:375.
-
(1973)
Lancet
, vol.1
, pp. 375
-
-
Beerman, B.1
-
74
-
-
0022397043
-
Bioavailability, gastrointestinal transit, solubilization and faecal excretion of urosodeoxycholic acid in man
-
Parquet M, Metman EH, Raizman A, Rambaud JC, Berthaux N, Infante R: Bioavailability, gastrointestinal transit, solubilization and faecal excretion of urosodeoxycholic acid in man. Eur J Clin Invest 1985;15:171-178.
-
(1985)
Eur J Clin Invest
, vol.15
, pp. 171-178
-
-
Parquet, M.1
Metman, E.H.2
Raizman, A.3
Rambaud, J.C.4
Berthaux, N.5
Infante, R.6
-
75
-
-
0023598709
-
A double-peak phenomena in the pharmacokinetics of veralipride after oral administration: A double-site model for drug absorption
-
Plusquellec Y, Campistron G, Staveris S, Barre J, Jung L, Tillement JP, Houin G: A double-peak phenomena in the pharmacokinetics of veralipride after oral administration: a double-site model for drug absorption. J Pharmacokinet Biopharm 1987;15:225-239.
-
(1987)
J Pharmacokinet Biopharm
, vol.15
, pp. 225-239
-
-
Plusquellec, Y.1
Campistron, G.2
Staveris, S.3
Barre, J.4
Jung, L.5
Tillement, J.P.6
Houin, G.7
-
76
-
-
0021965444
-
Effect of ileal infusions on intralipid on gastrointestinal transit, ileal flow rate, and carbohydrate absorption in humans after ingestion of a liquid meal
-
Holgate AM, Read NW: Effect of ileal infusions on intralipid on gastrointestinal transit, ileal flow rate, and carbohydrate absorption in humans after ingestion of a liquid meal. Gastronenterology 1985; 88:1005-1011.
-
(1985)
Gastronenterology
, vol.88
, pp. 1005-1011
-
-
Holgate, A.M.1
Read, N.W.2
-
77
-
-
0023425558
-
The influence of variable gastric emptying and intestinal transit rates on the plasma level curve of cimetidine: An explanation for the double peak phenomenon
-
Oberle RL, Amidon GL: The influence of variable gastric emptying and intestinal transit rates on the plasma level curve of cimetidine: an explanation for the double peak phenomenon. J Pharmacokinet Biopharm 1987;15(5):529-544.
-
(1987)
J Pharmacokinet Biopharm
, vol.15
, Issue.5
, pp. 529-544
-
-
Oberle, R.L.1
Amidon, G.L.2
-
78
-
-
0029583114
-
Celiprolol double-peak occurrence and gastric motility: Nonlinear mixed effects modeling of bioavailability data obtained in dogs
-
Lipka E, Lee I-D, Langguth P, Spahn-Langguth H, Mutschler E, Amidon GL: Celiprolol double-peak occurrence and gastric motility: nonlinear mixed effects modeling of bioavailability data obtained in dogs. J Pharmacokinet Biopharm 1995;23(3):267-287.
-
(1995)
J Pharmacokinet Biopharm
, vol.23
, Issue.3
, pp. 267-287
-
-
Lipka, E.1
Lee, I.-D.2
Langguth, P.3
Spahn-Langguth, H.4
Mutschler, E.5
Amidon, G.L.6
-
79
-
-
0004580383
-
A double-peak phenomenon in the pharmacokinetics of alprazolam after oral administration
-
Wang Y, Roy A, Sun L, Lau CE; A double-peak phenomenon in the pharmacokinetics of alprazolam after oral administration. Drug Metab Dispos 1999;27(8):855-859.
-
(1999)
Drug Metab Dispos
, vol.27
, Issue.8
, pp. 855-859
-
-
Wang, Y.1
Roy, A.2
Sun, L.3
Lau, C.E.4
-
80
-
-
7344239301
-
In vivo evaluation of the absorption and gastrointestinal transit of avitriptan in fed and fasted subjects using gamma scintigraphy
-
Marathe PH, Sandefer EP, Kollia GE, Greene DS, Barbhaiya RH, Lipper RA, et al: In vivo evaluation of the absorption and gastrointestinal transit of avitriptan in fed and fasted subjects using gamma scintigraphy. J Pharmacokinet Biopharm 1998;26(1):1-9.
-
(1998)
J Pharmacokinet Biopharm
, vol.26
, Issue.1
, pp. 1-9
-
-
Marathe, P.H.1
Sandefer, E.P.2
Kollia, G.E.3
Greene, D.S.4
Barbhaiya, R.H.5
Lipper, R.A.6
-
81
-
-
0027730875
-
Absorption of danazol after administration to different sites of the gastrointestinal tract and the relationship to single- and double-peak phenomena in the plasma profiles
-
Charman WN, Rogge M, Boddy AW, Barr WH, Berger BM: Absorption of danazol after administration to different sites of the gastrointestinal tract and the relationship to single- and double-peak phenomena in the plasma profiles. J Clin Pharmucol 1993;33:1207-1213.
-
(1993)
J Clin Pharmucol
, vol.33
, pp. 1207-1213
-
-
Charman, W.N.1
Rogge, M.2
Boddy, A.W.3
Barr, W.H.4
Berger, B.M.5
-
82
-
-
0027097541
-
Models for describing absorption rate and estimating extent of bioavailability: Application to cefetamet pivoxil
-
Holford NH, Ambros RJ, Stoeckel K: Models for describing absorption rate and estimating extent of bioavailability: application to cefetamet pivoxil. J Pharmacokinet Biopharm 1992;20(5);421-442.
-
(1992)
J Pharmacokinet Biopharm
, vol.20
, Issue.5
, pp. 421-442
-
-
Holford, N.H.1
Ambros, R.J.2
Stoeckel, K.3
-
83
-
-
0025868537
-
Dose-dependent absorption and elimination of cefadroxil in man
-
Garrigues TM, Martin U, Peris-Ribera JE, Prescott LF: Dose-dependent absorption and elimination of cefadroxil in man. Eur J Clin Pharmacol 1991;41(2):179-183.
-
(1991)
Eur J Clin Pharmacol
, vol.41
, Issue.2
, pp. 179-183
-
-
Garrigues, T.M.1
Martin, U.2
Peris-Ribera, J.E.3
Prescott, L.F.4
-
84
-
-
0032848537
-
Mixed effect modeling of sumatriptan pharmacokinetics during development: II. From healthy subjects to phase 2 dose ranging in patients
-
Cosson VF, Fuseau E: Mixed effect modeling of sumatriptan pharmacokinetics during development: II. From healthy subjects to phase 2 dose ranging in patients. J Pharmacokinet Biopharm 1999; 27(2):149-171.
-
(1999)
J Pharmacokinet Biopharm
, vol.27
, Issue.2
, pp. 149-171
-
-
Cosson, V.F.1
Fuseau, E.2
-
85
-
-
0033812182
-
Use of nonlinear mixed effect modeling for the meta-analysis of preclinical pharmacokinetic data: Application to S 20342 in the rat
-
Bouzom F, Laveille C, Merdjan H, Jochemsen R: Use of nonlinear mixed effect modeling for the meta-analysis of preclinical pharmacokinetic data: application to S 20342 in the rat. J Pharm Sci 2000;89(5):603-613.
-
(2000)
J Pharm Sci
, vol.89
, Issue.5
, pp. 603-613
-
-
Bouzom, F.1
Laveille, C.2
Merdjan, H.3
Jochemsen, R.4
-
86
-
-
0029002949
-
Absorption behavior of sulpiride described using Weibull functions
-
Rietbrock S, Merz PG, Fuhr U, Harder S, Marschner JP, Loew D, et al: Absorption behavior of sulpiride described using Weibull functions. Int J Clin Pharmacol Ther 1995;33(5):299-303.
-
(1995)
Int J Clin Pharmacol Ther
, vol.33
, Issue.5
, pp. 299-303
-
-
Rietbrock, S.1
Merz, P.G.2
Fuhr, U.3
Harder, S.4
Marschner, J.P.5
Loew, D.6
-
87
-
-
0019206323
-
Physical interpretation of parameters in the Rosin-Rammler-Sperling-Weibull distribution for drug release from controlled-release dosage forms
-
Christensen FN, Hansen FG, Bechgaard H: Physical interpretation of parameters in the Rosin-Rammler-Sperling-Weibull distribution for drug release from controlled-release dosage forms. J Pharm Pharmacol 1980;32:580-582.
-
(1980)
J Pharm Pharmacol
, vol.32
, pp. 580-582
-
-
Christensen, F.N.1
Hansen, F.G.2
Bechgaard, H.3
-
88
-
-
0023634612
-
The use of Weibull distribution to describe the in vivo absorption kinetics
-
Piotrovskii VK: The use of Weibull distribution to describe the in vivo absorption kinetics. J Pharmacokinet Biopharm 1987;15(6): 681-686.
-
(1987)
J Pharmacokinet Biopharm
, vol.15
, Issue.6
, pp. 681-686
-
-
Piotrovskii, V.K.1
-
89
-
-
0027241766
-
Pharmacokinetics and bioavailability of medroxyprogesterone acetate in the dog and the rat
-
Smith D, Enever R, Dey M, Latta D, Weierstall R: Pharmacokinetics and bioavailability of medroxyprogesterone acetate in the dog and the rat. Biopharm Drug Dispos 1993;14:341-355.
-
(1993)
Biopharm Drug Dispos
, vol.14
, pp. 341-355
-
-
Smith, D.1
Enever, R.2
Dey, M.3
Latta, D.4
Weierstall, R.5
-
90
-
-
0028986095
-
Pharmacokinetics of amoxicillin coadministered with a salinepolyethylene glycol solution in healthy volunteers
-
Padoin C, Tod M, Brion N, Louchahi K, Le Gros V, Petitjean O: Pharmacokinetics of amoxicillin coadministered with a salinepolyethylene glycol solution in healthy volunteers. Biopharm Drug Dispos 1995;16:169-176.
-
(1995)
Biopharm Drug Dispos
, vol.16
, pp. 169-176
-
-
Padoin, C.1
Tod, M.2
Brion, N.3
Louchahi, K.4
Le Gros, V.5
Petitjean, O.6
-
91
-
-
0027996075
-
A double Weibull input function describes the complex absorption of sustained-release oral sodium valproate
-
Bressolle F, Gomeni R, Alric R, Royer-Morrot MJ, Necciari J: A double Weibull input function describes the complex absorption of sustained-release oral sodium valproate. J Pharm Sci 1994;83(10): 1461-1464.
-
(1994)
J Pharm Sci
, vol.83
, Issue.10
, pp. 1461-1464
-
-
Bressolle, F.1
Gomeni, R.2
Alric, R.3
Royer-Morrot, M.J.4
Necciari, J.5
-
92
-
-
0033345899
-
Effect of meal timing not critical for the pharmacokinetics of tegaserod (HTF919)
-
Zhou H, Khalilieh S, Lau H, Guerret M, Osborne S, Laurent A, McLeod J: Effect of meal timing not critical for the pharmacokinetics of tegaserod (HTF919). J Clin Pharmacol 1999;39(9):911-920.
-
(1999)
J Clin Pharmacol
, vol.39
, Issue.9
, pp. 911-920
-
-
Zhou, H.1
Khalilieh, S.2
Lau, H.3
Guerret, M.4
Osborne, S.5
Laurent, A.6
McLeod, J.7
-
93
-
-
0025084550
-
Pharmacokinetic modelling of the plasma concentration-time profile of the vitamin retinyl palmitate following intramuscular administration
-
Hartmann D, Gysel D, Dubach UC, Forgo I: Pharmacokinetic modelling of the plasma concentration-time profile of the vitamin retinyl palmitate following intramuscular administration. Biopharm Drug Disp 1990;11:689-700.
-
(1990)
Biopharm Drug Disp
, vol.11
, pp. 689-700
-
-
Hartmann, D.1
Gysel, D.2
Dubach, U.C.3
Forgo, I.4
-
94
-
-
0026003290
-
Theoretical model for both saturable rate and extent of absorption: Simulations of cefatrizine data
-
Couet WR, Reginer BG, Guedes JP, Tozer YN. Theoretical model for both saturable rate and extent of absorption: simulations of cefatrizine data. J Pharmacokinet Biopharm 1991;19:271-285.
-
(1991)
J Pharmacokinet Biopharm
, vol.19
, pp. 271-285
-
-
Couet, W.R.1
Reginer, B.G.2
Guedes, J.P.3
Tozer, Y.N.4
-
95
-
-
0013883801
-
Factors affecting the absorption of riboflavin in man
-
Levy G, Jusko WJ: Factors affecting the absorption of riboflavin in man. J Pharm Sci 1966;55:285-289.
-
(1966)
J Pharm Sci
, vol.55
, pp. 285-289
-
-
Levy, G.1
Jusko, W.J.2
-
97
-
-
0020320952
-
Michaelis-Menten absorption kinetics in drugs: Examples and implications
-
Wood JH, Thakker KM: Michaelis-Menten absorption kinetics in drugs: examples and implications. Eur J Clin Pharmacol 1982; 23:183-188.
-
(1982)
Eur J Clin Pharmacol
, vol.23
, pp. 183-188
-
-
Wood, J.H.1
Thakker, K.M.2
-
98
-
-
0030840844
-
Cefixime absorption kinetics after oral administration to humans
-
Liu XD, Xie L, Gao JP, Lai LS, Liu GD: Cefixime absorption kinetics after oral administration to humans. Eur J Drug Metab Phormacokinet 1997;22(2):185-188.
-
(1997)
Eur J Drug Metab Phormacokinet
, vol.22
, Issue.2
, pp. 185-188
-
-
Liu, X.D.1
Xie, L.2
Gao, J.P.3
Lai, L.S.4
Liu, G.D.5
-
99
-
-
0021949835
-
Bioavailability studies with ciglitazone in beagles: II. Effect of propantheline bromide and metoclopramide HCL on bioavailability of a tablet
-
Cox SR, Harrington EL, Capponi VJ: Bioavailability studies with ciglitazone in beagles: II. Effect of propantheline bromide and metoclopramide HCL on bioavailability of a tablet. Biopharmaceutics & Drug Disposition 1985;6:81-90.
-
(1985)
Biopharmaceutics & Drug Disposition
, vol.6
, pp. 81-90
-
-
Cox, S.R.1
Harrington, E.L.2
Capponi, V.J.3
-
101
-
-
0029973918
-
A novel extravascular input function for the assessment of drug absorption in bioavailability studies
-
Weiss M: A novel extravascular input function for the assessment of drug absorption in bioavailability studies. Pharm Res 1996;13(10):1547-1553.
-
(1996)
Pharm Res
, vol.13
, Issue.10
, pp. 1547-1553
-
-
Weiss, M.1
-
102
-
-
0029928466
-
Effects of cardiac output on disposition kinetics of sorbitol: Recirculatory modelling
-
Weiss M, Hubner GH, Hubner IG, Teichmann W: Effects of cardiac output on disposition kinetics of sorbitol: recirculatory modelling. Br J Clin Pharmacol 1996;41(4):261-268.
-
(1996)
Br J Clin Pharmacol
, vol.41
, Issue.4
, pp. 261-268
-
-
Weiss, M.1
Hubner, G.H.2
Hubner, I.G.3
Teichmann, W.4
-
103
-
-
0031224992
-
On the validity of the dispersion model of hepatic drug elimination when intravascular transit time densities are long-tailed
-
Weiss M, Stedtler C, Roberts MS: On the validity of the dispersion model of hepatic drug elimination when intravascular transit time densities are long-tailed. Bull Math Biol 1997;59(5):911-929.
-
(1997)
Bull Math Biol
, vol.59
, Issue.5
, pp. 911-929
-
-
Weiss, M.1
Stedtler, C.2
Roberts, M.S.3
-
104
-
-
0033639240
-
Commentary: Using the convection-dispersion model and transit time density functions in the analysis of organ distribution kinetics
-
Roberts MS, Anissimov YG, Weiss M: Commentary: using the convection-dispersion model and transit time density functions in the analysis of organ distribution kinetics. J Pharm Sci 2000; 89(12):1579-1586.
-
(2000)
J Pharm Sci
, vol.89
, Issue.12
, pp. 1579-1586
-
-
Roberts, M.S.1
Anissimov, Y.G.2
Weiss, M.3
-
105
-
-
0036335809
-
Pharmacokinetics of plasma enfuvirtide after subcutaneous administration to patients with human immunodeficiency virus: Inverse Gaussian density absorption and 2-compartment disposition
-
Zhang X, Nieforth K, Lang J-M, Rouzier-Panis R, Reynes J, Dorr A, et al: Pharmacokinetics of plasma enfuvirtide after subcutaneous administration to patients with human immunodeficiency virus: inverse Gaussian density absorption and 2-compartment disposition. Clin Pharmacol Ther 2002;72:10-19.
-
(2002)
Clin Pharmacol Ther
, vol.72
, pp. 10-19
-
-
Zhang, X.1
Nieforth, K.2
Lang, J.-M.3
Rouzier-Panis, R.4
Reynes, J.5
Dorr, A.6
-
107
-
-
10544236111
-
Oral absorpqtion characteristics and pharmacokinetics of colchicine in healthy volunteers after single and multiple doses
-
Ferron GM, Rochdi M, Jusko WJ, Scherrmann JM: Oral absorpqtion characteristics and pharmacokinetics of colchicine in healthy volunteers after single and multiple doses. J Clin Pharmacol 1996; 36(10):874-883.
-
(1996)
J Clin Pharmacol
, vol.36
, Issue.10
, pp. 874-883
-
-
Ferron, G.M.1
Rochdi, M.2
Jusko, W.J.3
Scherrmann, J.M.4
|