Increased activity of membrane glycoprotein PC-1 in the fibroblasts from non-insulin-dependent diabetes mellitus patients with insulin resistance

Diabetes Research and Clinical Practice

Volumn 45, Issue 1, 1999, Pages 25-30

  Teno, Shinichi ^a   Kanno, Hiroko ^a   Oga, Satoko ^a   Kumakura, Shinobu ^a   Kanamuro, Reiko ^a   Iwamoto, Yasuhiko ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

Insulin resistance; NIDDM; Plasma cell antigen 1 (PC 1)

Indexed keywords

MEMBRANE PROTEIN;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; INSULIN RESISTANCE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NORMAL HUMAN;

ADULT; AGED; BIOPSY; BLOOD GLUCOSE; CELLS, CULTURED; DIABETES MELLITUS, TYPE 2; FEMALE; FIBROBLASTS; GLUCOSE CLAMP TECHNIQUE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; INSULIN RESISTANCE; MALE; MEMBRANE GLYCOPROTEINS; MIDDLE AGED; PHOSPHORIC DIESTER HYDROLASES; PYROPHOSPHATASES; SCINTILLATION COUNTING; SKIN;

EID: 0032799097     PISSN: 01688227     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8227(99)00056-X     Document Type: Article

References (20)

1. Kahn C.R. Insulin action, diabetogenes, and the cause of type II diabetes. Diabetes. 43:1994;1066-1084.
2. Takahashi T., Old L.J., Boyse E.A. Surface alloantigens of plasma cells. J. Exp. Med. 131:1970;1325-1341.
3. Harahap A.R., Goding J.W. Distribution of the murine plasma cell antigen PC-1 in non-lymphoid tissue. J. Immunol. 141:1988;2317-2320.
4. Narita M., Goji J., Nakamura H., Sanak A. Molecular cloning expression and localization of a brain-specific phosphodiesterase I/nucleotide pyrophosphatase (PD-I alfa) from rat brain. J. Biol. Chem. 269:1994;28235-28242.
5. Maddux B.A., Sbraccia P., Kumakura S. et al. Membrane glycoprotein PC1 and insulin resistance in non-insulin-dependent diabetes mellitus. Nature. 373:1995;448-451.
6. Belfiore A., Costantino A., Frasca F. et al. Overexpression of membrane glycoprotein PC-1 in MDA-MB231 breast cancer cells is associated with inhibition of insulin receptor tyrosine kinase activity. Mol. Endocrinol. 10:1996;1318-1326.
7. Sbraccia P., Goodman P.A., Maddux B.A. et al. Production of inhibitor of insulin-receptor tyrosine kinase in fibroblasts from patient with insulin resistance and NIDDM. Diabetes. 40:1996;295-299.
8. Maddux B.A., Sbraccia P., Reaven G.M., Moller D.E., Goldfine I.D. Inhibitors of insulin receptor tyrosine kinase in fibroblasts from diverse patients with impaired insulin action: evidence for a novel mechanism of postreceptor insulin resistance. J. Clin. Endocrinol. Metab. 77:1993;73-79.
9. DeFronzo R.A., Tobin J.D., Andres R. et al. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am. J. Physiol. 237:1979;E214-E223.
10. DeFronzo R.A., Ferrannini E., Koivisto V. et al. New concepts in the pathogenesis and treatment of non-insulin-dependent diabetes mellitus. Am. J. Med. 74:1983;52-81.
11. Olefsky J.M., Ciaraldi T.P., Kolterman O.G. et al. Mechanism of insulin resistance in non-insulin-dependent (type II) diabetes. Am. J. Med. 75:1985;23-31.
12. Frittitta F., Youngren J.F., Vigneri R., Maddux B.A., Trischitta V., Goldfine I.D. PC-1 content in skeletal muscle of non-obese, non-diabetic subjects: relationship to insulin receptor tyrosine kinase and whole body insulin sensitivity. Diabetologia. 39:1996;1190-1195.
13. Youngren J.F., Maddux B.A., Sasson S. et al. Skeletal muscle content of membrane glycoprotein PC-1 in obesity. Diabetes. 45:1996;1324-1328.
14. Frittitta L., Youngren J.F., Sbraccia P. et al. Increased adipose tissue PC-1 protein content, but not tumour necrosis factor-alfa gene expression, is associated with a reduction of both whole body insulin sensitivity and insulin receptor tyrosine-kinase activity. Diabetologia. 40:1997;282-289.
15. Haring H., Obermaier-Kusser B. Insulin receptor kinase defects in insulin-resistant tissues and their role in the pathogenesis of NIDDM. Diabetes Metab. Rev. 5:1989;431-441.
16. Frittitta L., Spampinato D., Solini A. et al. Elevated PC-1 content in cultured skin fibroblasts correlates with decreased in vivo and in vitro insulin action in non-diabetic subjects: evidence that PC-1 may be an intrinsic factor in impaired insulin receptor signalling. Diabetes. 47:1998;1095-1100.
17. Goding J.W., Shen F.W. Structure of the murine plasma cell alloantigen PC-1: comparison with the receptor for transferrin. J. Immunol. 129:1982;2636-2640.
18. van Driel I.R., Goding J.W. Plasma cell membrane glycoprotein PC-1 primary structure deduced from cDNA clones. J. Biol. Chem. 262:1987;4882-4887.
19. Singer S.J., Maher P.A., Yaffe M.P. On the transfer of integral proteins into membranes. Proc. Natl. Acad. Sci. USA. 84:1987;1960-1964.
20. Grupe A., Alleman J., Goldfine I.D., Sadick M., Stewart T.A. Inhibition of insulin receptor phosphorylation by PC-1 is not mediated by the hydrolysis of adenosine triphosphate or the generation of adenosine. J. Biol. Chem. 38:1995;22085-22088.