Elevated PC-1 content in cultured skin fibroblasts correlates with decreased in vivo and in vitro insulin action in nondiabetic subjects: Evidence that PC-1 may be an intrinsic factor in impaired insulin receptor signaling

Diabetes

Volumn 47, Issue 7, 1998, Pages 1095-1100

  Frittitta, Lucia ^a   Spampinato, Daniela ^a   Solini, Anna ^b   Nosadini, Romano ^b   Goldfine, Ira D ^d   Vigneri, Riccardo ^a   Trischitta, Vincenzo ^a,c  

^a UNIVERSITY OF CATANIA   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

^c Ricerca di Endocrinologia   (Italy)

^d UNIVERSITY OF SAN FRANCISCO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; INTRINSIC FACTOR;

ARTICLE; AUTOPHOSPHORYLATION; DIABETES MELLITUS; DRUG RECEPTOR BINDING; ENZYME ACTIVITY; HORMONE ACTION; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; INSULIN BINDING; INSULIN RESISTANCE; METABOLIC DISORDER; PRIORITY JOURNAL; SKIN FIBROBLAST; TARGET CELL;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADULT; CELLS, CULTURED; CHOLESTEROL; FASTING; FEMALE; FIBROBLASTS; GLUCOSE; GLYCOGEN; HUMANS; INSULIN; INSULIN RESISTANCE; MALE; MEMBRANE GLYCOPROTEINS; MIDDLE AGED; MUSCLES; PHOSPHORIC DIESTER HYDROLASES; PYROPHOSPHATASES; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION; SKIN;

EID: 0031747108     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.47.7.1095     Document Type: Article

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