PC-1 content in skeletal muscle of non-obese, non-diabetic subjects: Relationship to insulin receptor tyrosine kinase and whole body insulin sensitivity

Diabetologia

Volumn 39, Issue 10, 1996, Pages 1190-1195

  Frittitta, L ^a   Youngren, J ^b   Vigneri, R ^a   Maddux, B A ^b   Trischitta, V ^a,c   Goldfine, I D ^b  

^a UNIVERSITY OF CATANIA   (Italy)

^b UNIVERSITY OF SAN FRANCISCO   (United States)

^c GARIBALDI HOSPITAL   (Italy)

Author keywords

Insulin receptor tyrosine kinase activity; Insulin sensitivity; Insulin signalling; Insulin tolerance test; Skeletal muscle

Indexed keywords

GLYCOPROTEIN; INSULIN RECEPTOR KINASE; PC 1; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; MALE; PRIORITY JOURNAL; RADIOIMMUNOASSAY; SKELETAL MUSCLE;

EID: 0029759418     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02658505     Document Type: Article

References (32)

1. Reaven G (1988) Role of insulin resistance in human disease. Diabetes 37: 1595-1607
2. DeFronzo RA, Bonadonna RC, Ferrannini E (1992) Pathogenesis of NIDDM. A balanced overview. Diabetes Care 15: 318-368
3. Bogardus C (1993) Insulin resistance in the pathogenesis of NIDDM in Pima Indians. Diabetes Care 16 [Suppl 1]: 228-231
4. Taylor SI (1994) Insulin resistance or insulin deficiency: which is the primary cause of NIDDM? Diabetes 43: 735-740
5. Beck-Nielsen H, Groop LC (1994) Metabolic and genetic characterization of prediabetic states. J Clin Invest 94: 1714-1721
6. Kahn RC (1994) Insulin action, diabetogenes, and the cause of type II diabetes. Diabetes 43: 1066-1084
7. Olefsky JM, Nolan JJ (1995) Insulin resistance and non-insulin-dependent diabetes mellitus: cellular and molecular mechanisms. Am J Clin Nutr 61 [Suppl]: 980S-986S
8. Häring HU (1991) The insulin receptor: signalling mechanism and contribution to the pathogenesis of insulin resistance. Diabetologia 34: 848-861
9. Grasso G, Frittitta L, Anello M, Russo P, Sesti G, Trischitta V (1995) Insulin receptor tyrosine-kinase activity is altered in both muscle and adipose tissue from nonobese normoglycemic insulin resistant subjects. Diabetologia 38: 55-61
10. Frittitta L, Grasso G, Munguira E, Vigneri R, Trischitta V (1993) Insulin receptor tyrosine-kinase activity is reduced in monocytes from non-obese normoglycaemic insulin resistant subjects. Diabetologia 36: 1163-1167
11. Sbraccia P, Goodman PA, Maddux BA et al. (1991) Production of inhibitor of insulin-receptor tyrosine-kinase in fibroblasts from patient with insulin resistance and NIDDM. Diabetes 40: 295-299
12. Maddux BA, Sbraccia P, Kumakura S et al. (1995) Membrane glycoprotein PC-1 and insulin resistance in non-insulin-dependent diabetes mellitus. Nature 373: 448-451
13. Whitehead JP, Humphreys PJ, Maasen JA, Poller DE, Krok A, O'Rahilly S (1995) Increased PC-1 phosphodiesterase activity in patients with post-receptor insulin resistance but not in patients with insulin receptor mutations. Diabetologia 38 [Suppl 1]: 65A Abstract
14. Grupe A, Alleman J, Goldfine ID, Sadick M, Stewart TA (1995) Inhibition of insulin receptor phosphorylation by PC-1 is not mediated by the hydrolysis of adenosine triphosphate or the generation of adenosine. J Biol Chem 270: 22085-22088
15. Bonora E, Moghetti P, Zancanaro C et al. (1989) Estimates of in vivo insulin action in man: comparison of insulin tolerance test with euglycemic and hyperglycemic glucose clamp studies. J Clin Endocrinol Metab 68: 374-378
16. Pezzino V, Papa V, Trischitta V et al. (1989) Human insulin receptor radioimmunoassay: applicability to insulin resistant state. Am J Physiol 257: 451-457
17. Steele-Perkins G, Roth RA (1990) Insulin-mimetic anti-insulin receptor monoclonal antibodies stimulate receptor kinase activity in intact cells. J Biol Chem 265: 9458-9463
18. Bradford MM (1976) A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254
19. Caro JF, Sinha MK, Raju SM et al. (1987) Insulin receptor kinase in human skeletal muscle from obese subjects with and without noninsulin dependent diabetes. J Clin Invest 79: 1330-1337
20. Arner P, Pollare T, Lithell H, Livingstone JN (1987) Defective insulin receptor tyrosine-kinase in human skeletal muscle in obesity and type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia 30: 437-440
21. Obermaier-Kusser B, White MF, Pongratz DE et al. (1989) A defective intramolecular autoactivation cascade may cause the reduced kinase activity of the skeletal muscle insulin receptor from patients with non-insulin-dependent diabetes mellitus. J Biol Chem 264: 9497-9504
22. Maegawa H, Shigeta Y, Egawa K, Kohayashi M (1991) Impaired autophosphorylation of insulin receptors from ab-dominal skeletal muscle in non-obese subjects with NIDDM. Diabetes 40: 815-819
23. Handberg A, Vaag A, Vincent J, Beck-Nielsen H (1993) Decreased tyrosine kinase activity in partially purified insulin receptor from skeletal muscle of young, non-obese first degree relatives of patients with type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia 36: 668-674
24. Nyomba BL, Ossowski VM, Bogardus C, Mott DM (1990) Insulin-sensitive tyrosine-kinase: relationship with in vivo insulin action in humans. Am J Physiol 258: (Endocrinol Metab 21): E964-E974
25. Nolan JJ, Freidenberg G, Henry R, Reichart D, Olefsky JM (1994) Role of human skeletal muscle receptor kinase in the in vivo insulin resistance of noninsulin-dependent diabetes mellitus and obesity. J Clin Endocrinol Metab 78: 471-477
26. Klein HH, Vestergaard H, Kotzke G, Pedersen O (1995) Elevation of serum insulin concentration during euglycemic hyperinsulinemic clamp studies leads to similar activation of insulin receptor kinase in skeletal muscle of subjects with and without NIDDM. Diabetes 44: 1310-1317
27. Taylor SI, Cama A, Accili D et al. (1992) Mutations in the insulin receptor gene. Endocr Rev 13: 566-595
28. Rebbe NF, Tong BD, Hickman S (1993) Expression of nucleotide pyrophosphatase I activities of PC-1, the murine plasma cell antigen. Mol Immunol 30: 87-93
29. Murata JM, Lee HY, Clair T et al. (1994) cDNA Cloning of the human tumor motility-stimulating protein, autotaxin, reveals a homology with phosphodiesterase. J Biol Chem 269: 30479-30485
30. Harap AR, Goding JW (1988) Distribution of the murine plasma cell antigen PC-1 in non-lymphoid tissues. J Immunol 141: 2317-2320
31. Belli SI, Goding JW (1994) Biochemical characterization of human PC-1, an enzyme possessing alkaline phosphodiesterase I and nucleotide pyrophosphatase activities. Eur J Biochem 226: 433-443
32. Funakoshi I, Kato H, Horie et al. (1992) Molecular cloning of cDNAs for human fibroblast nucleotide pyrophosphatase. Arch Biochem Biophys 295: 180-187