A mutant receptor tyrosine phosphatase, CD148, causes defects in vascular development

Molecular and Cellular Biology

Volumn 23, Issue 5, 2003, Pages 1817-1831

  Takahashi, Takamune ^a   Takahashi, Keiko ^a   St John, Patricia L ^b   Fleming, Paul A ^c   Tomemori, Takuya ^d   Watanabe, Toshio ^f   Abrahamson, Dale R ^b   Drake, Christopher J ^c   Shirasawa, Takuji ^e   Daniel, Thomas O ^d  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^d AMGEN INC   (United States)

^e TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^f TOHOKU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN RECEPTOR; CD148 PHOSPHATASE; CD31 ANTIGEN; CELL MARKER; ENDOGLIN; EPHRIN; GREEN FLUORESCENT PROTEIN; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 2; WHEAT GERM AGGLUTININ;

ANGIOGENESIS; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL INTERACTION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; ENDOCARDIUM; GENETIC RECOMBINATION; MOUSE; NONHUMAN; NORTHERN BLOTTING; PERICYTE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VASCULAR ENDOTHELIUM; VASCULARIZATION;

ALLELES; ANIMALS; ANTIGENS, CD31; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CATALYSIS; CATALYTIC DOMAIN; CELL DIVISION; CYTOPLASM; DNA-BINDING PROTEINS; ENDOTHELIUM, VASCULAR; EPHRIN-B2; GREEN FLUORESCENT PROTEINS; HOMOZYGOTE; KIDNEY; LUMINESCENT PROTEINS; MICE; MICROSCOPY, ELECTRON; MODELS, GENETIC; MUTATION; MYOCARDIUM; PRECIPITIN TESTS; PROTEIN-TYROSINE-PHOSPHATASE; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, TIE-2; RECOMBINANT FUSION PROTEINS; RECOMBINATION, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TIME FACTORS; TRANSCRIPTION FACTORS; TYROSINE; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

ANIMALIA; TRITICUM AESTIVUM;

EID: 0037369897     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.23.5.1817-1831.2003     Document Type: Article

References (54)

1. Adams, R. H. 2002. Vascular patterning by Eph receptor tyrosine kinases and ephrins. Semin. Cell Dev. Biol. 13:55-60.
2. Baker, J. E., R. Majeti, S. G. Tangye, and A. Weiss. 2001. Protein tyrosine phosphatase CD148-mediated inhibition of T-cell receptor signal transduction is associated with reduced LAT and phospholipase Cγ1 phosphorylation. Mol. Cell. Biol. 21:2393-2403.
3. Barbara, N. P., J. L. Wrana, and M. Letarte. 1999. Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily. J. Biol. Chem. 274:584-594.
4. Begley, C. G., P. D. Aplan, S. M. Denning, B. F. Haynes, T. A. Waldmann, and I. R. Kirsch. 1989. The gene SCL is expressed during early hematopoiesis and encodes a differentiation-related DNA-binding motif. Proc. Natl. Acad. Sci. USA 86:10128-10132.
5. Bi, W., C. J. Drake, and J. J. Schwarz. 1999. The transcription factor MEF2C-null mouse exhibits complex vascular malformations and reduced cardiac expression of angiopoietin 1 and VEGF. Dev. Biol. 211:255-267.
6. Bianchi, C., F. W. Sellke, R. L. Del Vecchio, N. K. Tonks, and B. G. Neel. 1999. Receptor-type protein-tyrosine phosphatase mu is expressed in specific vascular endothelial beds in vivo. Exp. Cell Res. 248:329-338.
7. Borges, L. G., R. A. Seifert, F. J. Grant, C. E. Hart, C. M. Disteche, S. Edelhoff, F. F. Solca, M. A. Lieberman, V. Lindner, E. H. Fischer, S. Lok, and D. F. Bowen-Pope. 1996. Cloning and characterization of rat densityenhanced phosphatase-1, a protein tyrosine phosphatase expressed by vascular cells. Circ. Res. 79:570-580.
8. Bourdeau, A., D. J. Dumont, and M. Letarte. 1999. A murine model of hereditary hemorrhagic telangiectasia. J. Clin. Investig. 104:1343-1351.
9. Brady-Kalnay, S. M., D. L. Rimm, and N. K. Tonks. 1995. Receptor protein tyrosine phosphatase PTPμ associates with cadherins and catenins in vivo. J. Cell Biol. 130:977-986.
10. Carmeliet, P. 2000. Mechanisms of angiogenesis and arteriogenesis. Nat. Med. 6:389-395.
11. Daniel, T. O., and D. Abrahamson. 2000. Endothelial signal integration in vascular assembly. Annu. Rev. Physiol. 62:649-671.
12. de la Fuente-Garcia, M. A., J. M. Nicolas, J. H. Freed, E. Palou, A. P. Thomas, R. Vilella, J. Vives, and A. Gaya. 1998. CD148 is a membrane protein tyrosine phosphatase present in all hematopoietic lineages and is involved in signal transduction on lymphocytes. Blood 91:2800-2809.
13. Desai, C. J., Q. Sun, and K. Zinn. 1997. Tyrosine phosphorylation and axon guidance: of mice and flies. Curt. Opin. Neurobiol. 7:70-74.
14. Drake, C. J., S. J. Brandt, T. C. Trusk, and C. D. Little. 1997. TAL1/SCL is expressed in endothelial progenitor cells/angioblasts and defines a dorsal-toventral gradient of vasculogenesis. Dev. Biol. 192:17-30.
15. Drake, C. J., and P. A. Fleming. 2000. Vasculogenesis in the day 6.5 to 9.5 mouse embryo. Blood 95:1671-1679.
16. Drake, C. J., A. LaRue, N. Ferrara, and C. D. Little. 2000. VEGF regulates cell behavior during vasculogenesis. Dev. Biol. 224:178-188.
17. Fachinger, G., U. Deutsch, and W. Risau. 1999. Functional interaction of vascular endothelial-protein-tyrosine phosphatase with the angiopoietin receptor Tie-2. Oncogene 18:5948-5953.
18. Ferrara, N. 2001. Role of vascular endothelial growth factor in regulation of physiological angiogenesis. Am. J. Physiol. Cell Physiol. 280:C1358-C1366.
19. Godwin, A. R., H. S. Stadler, K. Nakamura, and M. R. Capecchi. 1998. Detection of targeted GFP-Hox gene fusions during mouse embryogenesis. Proc. Natl. Acad. Sci. USA 95:13042-13047.
20. Hadjantonakis, A. K., M. Gertsenstein, M. Ikawa, M. Okabe, and A. Nagy. 1998. Generating green fluorescent mice by germline transmission of green fluorescent ES cells. Mech. Dev. 76:79-90.
21. Hellstrom, M., H. Gerhardt, M. Kalen, X. Li, U. Eriksson, H. Wolburg, and C. Betsholtz. 2001. Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis. J. Cell Biol. 153:543-553.
22. Hirschi, K. K., S. A. Rohovsky, and P. A. D'Amore. 1997. Cell-cell interactions in vessel assembly: a model for the fundamentals of vascular remodelling. Transplant Immunol. 5:177-178.
23. Jones, N., K. Iljin, D. J. Dumont, and K. Alitalo. 2001. Tie receptors: new modulators of angiogenic and lymphangiogenic responses. Nat. Rev. Mol. Cell Biol. 2:257-267.
24. Jonker, L., and H. M. Arthur. 2002. Endoglin expression in early development is associated with vasculogenesis and angiogenesis. Mech. Dev. 110:193-196.
25. 3CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol. Cell. Biol. 20:4106-4114.
26. Kallianpur, A. R., J. E. Jordan, and S. J. Brandt. 1994. The SCL/TAL-1 gene is expressed in progenitors of both the hematopoietic and vascular systems during embryogenesis. Blood 83:1200-1208.
27. Keane, M. M., G. A. Lowrey, S. A. Ettenberg, M. A. Dayton, and S. Lipkowitz. 1996. The protein tyrosine phosphatase DEP-1 is induced during differentiation and inhibits growth of breast cancer cells. Cancer Res. 56:4236-4243.
28. Krebs, L. T., Y. Xue, C. R. Norton, J. R. Shutter, M. Maguire, J. P. Sundberg, D. Gallahan, V. Closson, J. Kitajewski, R. Callahan, G. H. Smith, K. L. Stark, and T. Gridley. 2000. Notch signaling is essential for vascular morphogenesis in mice. Genes Dev. 14:1343-1352.
29. Kume, T., T. Watanabe, R. Sanokawo, D. Chida, T. Nakamura, and M. Oishi. 1996. Expression of the protein tyrosine phosphatase β32 gene in mouse erythroleukemia cells induces terminal erythroid differentiation. J. Biol. Chem. 271:30916-30921.
30. Kuramochi, S., S. Matsuda, Y. Matsuda, T. Saitoh, M. Ohsugi, and T. Yamamoto. 1996. Molecular cloning and characterization of Byp, a murine receptor-type tyrosine phosphatase similar to human DEP-1. FEBS Lett. 378:7-14.
31. Li, C., I. N. Hampson, L. Hampson, P. Kumar, C. Bernabeu, and S. Kumar. 2000. CD105 antagonizes the inhibitory signaling of transforming growth factor β1 on human vascular endothelial cells. FASEB J. 14:55-64.
32. Li, D. Y., L. K. Sorensen, B. S. Brooke, L. D. Urness, E. C. Davis, D. G. Taylor, B. B. Boak, and D. P. Wendel. 1999. Defective angiogenesis in mice lacking endoglin. Science 284:1534-1537.
33. Lindahl, P., H. Bostrom, L. Karlsson, M. Hellstrom, M. Kalen, and C. Betsholtz. 1999. Role of platelet-derived growth factors in angiogenesis and alveogenesis. Curr. Top. Pathol. 93:27-33.
34. Oh, S. P., T. Seki, K. A. Goss, T. Imamura, Y. Yi, P. K. Donahoe, L. Li, K. Miyazono, P. ten Dijke, S. Kim, and E. Li. 2000. Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis. Proc. Natl. Acad. Sci. USA 97:2626-2631.
35. Oshima, M., H. Oshima, and M. M. Taketo. 1996. TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis. Dev. Biol. 179:297-302.
36. Ostman, A., Q. Yang, and N. K. Tonks. 1994. Expression of DEP-1, a receptor-like protein-tyrosine-phosphatase, is enhanced with increasing cell density. Proc. Natl. Acad. Sci. USA 91:9680-9684.
37. Papetti, M., and I. M. Herman. 2002. Mechanisms of normal and tumorderived angiogenesis. Am. J. Physiol. Cell Physiol. 282:C947-C970.
38. Pereira, F. A., Y. Qiu, G. Zhou, M. J. Tsai, and S. Y. Tsai. 1999. The orphan nuclear receptor COUP-TFII is required for angiogenesis and heart development. Genes Dev. 13:1037-1049.
39. Piston, D. W., G. H. Patterson, and S. M. Knobel. 1999. Quantitative imaging of the green fluorescent protein (GFP). Methods Cell Biol. 58:31-48.
40. Ruivenkamp, C. A., T. Van Wezel, C. Zanon, A. P. Stassen, C. Vlcek, T. Csikos, A. M. Klous, N. Tripodis, A. Perrakis, L. Boerrigter, P. C. Groot, J. Lindeman, W. J. Mooi, G. A. Meijjer, G. Scholten, H. Dauwerse, V. Paces, N. Van Zandwijk, G. J. Van Ommen, and P. Demant. 2002. Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancers. Nat. Genet. 31:295-300.
41. Sap, J., Y.-P. Jiang, D. Friedlander, M. Grumet, and J. Schlessinger. 1994. Receptor tyrosine phosphatase R-PTP-κ mediates homophilic binding. Mol. Cell. Biol. 14:1-9.
42. Schlaeger, T. M., Y. Qin, Y. Fujiwara, J. Magram, and T. N. Sato. 1995, Vascular endothelial cell lineage-specific promoter in transgenic mice. Development 121:1089-1098.
43. Suzuki, E., D. Nagata, M. Yoshizumi, M. Kakoki, A. Goto, M. Omata, and Y. Hirata. 2000. Reentry into the cell cycle of contact-inhibited vascular endothelial cells by a phosphatase inhibitor. Possible involvement of extracellular signal-regulated kinase and phosphatidylinositol 3-kinase. J. Biol. Chem. 275:3637-3644.
44. Takahashi, N., A. Haba, F. Matsuno, and B. K. Seon. 2001. Antiangiogenic therapy of established tumors in human skin/severe combined immunodeficiency mouse chimeras by anti-endoglin (CD105) monoclonal antibodies, and synergy between anti-endoglin antibody and cyclophosphamide. Cancer Res. 61:7846-7854.
45. Takahashi, T., K. Takahashi, R. Mernaugh, V. Drozdoff, C. Sipe, H. Schoecklmann, B. Robert, D. R. Abrahamson, and T. O. Daniel. 1999. Endothelial localization of receptor tyrosine phosphatase, ECRTP/DEP-1, in developing and mature renal vasculature. J. Am. Soc. Nephrol. 10:2135-2145.
46. Takahashi, Y., T. Imanaka, and T. Takano. 1996. Spatial and temporal pattern of smooth muscle cell differentiation during development of the vascular system in the mouse embryo. Anat. Embryol. (Berlin) 194:515-526.
47. Kip1. Mol. Cell. Biol. 20:9236-9246.
48. Van Vactor, D. 1998. Protein tyrosine phosphatases in the developing nervous system. Curr. Opin. Cell Biol. 10:174-181.
49. Wang, H. U., Z. F. Chen, and D. J. Anderson. 1998. Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4. Cell 93:741-753.
50. Wartenberg, M., J. Gunther, J. Hescheler, and H. Sauer. 1998. The embryoid body as a novel in vitro assay system for antiangiogenic agents. Lab. Investig. 78:1301-1314.
51. Xue, Y., X. Gao, C. E. Lindsell, C. R. Norton, B. Chang, C. Hicks, M. Gendron-Maguire, E. B. Rand, G. Weinmaster, and T. Gridley. 1999. Embryonic lethality and vascular defects in mice lacking the Notch ligand Jaggedl. Hum. Mol. Genet. 8:723-730.
52. Yagi, T., S. Nada, N. Watanabe, H. Tamemoto, N. Kohmura, Y. Ikawa, and S. Aizawa. 1993. A novel negative selection for homologous recombinants using diphtheria toxin A fragment gene. Anal. Biochem. 214:77-86.
53. Zhang, L., M. L. Martelli, C. Battaglia, F. Trapasso, D. Tramontano, G. Viglietto, A. Porcellini, M. Santoro, and A. Fusco. 1997. Thyroid cell transformation inhibits the expression of a novel rat protein tyrosine phosphatase. Exp. Cell Res. 235:62-70.
54. Zhao, G. Q., K. Deng, P. A. Labosky, L. Liaw, and B. L. Hogan. 1996. The gene encoding bone morphogenetic protein 8B is required for the initiation and maintenance of spermatogenesis in the mouse. Genes Dev. 10:1657-1669.