메뉴 건너뛰기




Volumn 4, Issue 3, 2003, Pages 397-405

Long-term use of sildenafil

Author keywords

Erectile dysfunction; Phosphodiesterase inhibitors; Sildenafil

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; ANTIALLERGIC AGENT; ANTIBIOTIC AGENT; ANTIDEPRESSANT AGENT; ANTIHYPERTENSIVE AGENT; APOMORPHINE; ARGININE; AZITHROMYCIN; CIMETIDINE; CYCLIC GMP; CYTOCHROME P450; CYTOCHROME P450 INHIBITOR; ERYTHROMYCIN; KETOCONAZOLE; MACROLIDE; PHENTOLAMINE; PHOSPHODIESTERASE; PHOSPHODIESTERASE INHIBITOR; PLACEBO; PROSTAGLANDIN E1; PROTEINASE INHIBITOR; RITONAVIR; SAQUINAVIR; SILDENAFIL; TADALAFIL; TRAZODONE; UNINDEXED DRUG; VARDENAFIL; YOHIMBINE; ZAPRINAST;

EID: 0037350305     PISSN: 14656566     EISSN: None     Source Type: Journal    
DOI: 10.1517/14656566.4.3.397     Document Type: Review
Times cited : (20)

References (46)
  • 1
    • 0027198755 scopus 로고
    • Impotence
    • NIH Consensus Conference. NIH Consensus Development Panel on Impotence
    • NIH Consensus Conference. Impotence. NIH Consensus Development Panel on Impotence. JAMA (1995) 270:83-90.
    • (1995) JAMA , vol.270 , pp. 83-90
  • 2
    • 0028036149 scopus 로고
    • Impotence and its medical and psychological correlates: Results of the Massachusetts Male Aging Study
    • FELDMAN AH, GOLDSTEIN I, HATZICHRISTOU DG et al.: Impotence and its medical and psychological correlates: results of the Massachusetts Male Aging Study. J. Urol. (1994) 151:54-61.
    • (1994) J. Urol. , vol.151 , pp. 54-61
    • Feldman, A.H.1    Goldstein, I.2    Hatzichristou, D.G.3
  • 3
    • 0001782609 scopus 로고    scopus 로고
    • Prevalence and correlates of erectile dysfunction. A United States nationwide population base sample: Phase I results
    • CARSON CC, WEST SL, GLASSER DB et al.: Prevalence and correlates of erectile dysfunction. A United States nationwide population base sample: Phase I results. J. Urol. (2002) 167:29.
    • (2002) J. Urol. , vol.167 , pp. 29
    • Carson, C.C.1    West, S.L.2    Glasser, D.B.3
  • 4
    • 0033941058 scopus 로고    scopus 로고
    • Modifiable risk factors and erectile dysfunction: Can a lifestyle change modify risk?
    • DERBY CA, MOHR BA, GOLDSTEIN I et al.: Modifiable risk factors and erectile dysfunction: can a lifestyle change modify risk? Urology (2000) 56:302-306.
    • (2000) Urology , vol.56 , pp. 302-306
    • Derby, C.A.1    Mohr, B.A.2    Goldstein, I.3
  • 5
    • 0028860594 scopus 로고
    • The epidemiology of erectile dysfunction
    • BENET AE, MELMAN A: The epidemiology of erectile dysfunction. Urol. Clin. North Am. (1975) 2:699-709.
    • (1975) Urol. Clin. North Am. , vol.2 , pp. 699-709
    • Benet, A.E.1    Melman, A.2
  • 7
    • 0343580432 scopus 로고    scopus 로고
    • Therapeutic effects of high dose yohimbine hydrochloride on organic erectile dysfunction
    • TELOKEN C, RHODEN E, SOGARI P et al.: Therapeutic effects of high dose yohimbine hydrochloride on organic erectile dysfunction. J. Urol. (1998) 159:122-124.
    • (1998) J. Urol. , vol.159 , pp. 122-124
    • Teloken, C.1    Rhoden, E.2    Sogari, P.3
  • 8
    • 0023270717 scopus 로고
    • Is yohimbine effective in the treatment of organic impotence?
    • MORALES A, CONDRA M, OWEN J et al.: Is yohimbine effective in the treatment of organic impotence? J. Urol. (1987) 137:1168-1172.
    • (1987) J. Urol. , vol.137 , pp. 1168-1172
    • Morales, A.1    Condra, M.2    Owen, J.3
  • 9
    • 0026057834 scopus 로고
    • Pathophysiology of prolonged penile erection associated with trazodone use
    • SAENZDETEJADA I, WARE JC, BIANCO R et al.: Pathophysiology of prolonged penile erection associated with trazodone use. J. Urol. (1991) 145:60-64.
    • (1991) J. Urol. , vol.145 , pp. 60-64
    • Saenzdetejada, I.1    Ware, J.C.2    Bianco, R.3
  • 10
    • 0023840023 scopus 로고
    • Priapism associated with trazodone therapy
    • CARSON CC, MINO RD: Priapism associated with trazodone therapy. J. Urol. (1988) 139:369-370.
    • (1988) J. Urol. , vol.139 , pp. 369-370
    • Carson, C.C.1    Mino, R.D.2
  • 11
    • 0028386686 scopus 로고
    • Effective large doses of the NO precursor L-arginine on erectile function
    • ZORGNIOTTI A, LIZZA E: Effective large doses of the NO precursor L-arginine on erectile function. Int. J. Impot. Res. (1994) 6:33-35.
    • (1994) Int. J. Impot. Res. , vol.6 , pp. 33-35
    • Zorgniotti, A.1    Lizza, E.2
  • 12
    • 0033035004 scopus 로고    scopus 로고
    • Effective oral administration of high dose nitric oxide donor L-arginine in men with organic erectile dysfunction: Results of a double blind randomized placebo controlled study
    • CHEN J, WOLLMAN Y, CHERNICHOVSKY T, IAINA A, SOFER M, MATZKIN H: Effective oral administration of high dose nitric oxide donor L-arginine in men with organic erectile dysfunction: results of a double blind randomized placebo controlled study. BJU. Int. (1999) 83:269-271.
    • (1999) BJU. Int. , vol.83 , pp. 269-271
    • Chen, J.1    Wollman, Y.2    Chernichovsky, T.3    Iaina, A.4    Sofer, M.5    Matzkin, H.6
  • 13
  • 14
    • 0035258441 scopus 로고    scopus 로고
    • Key issues from the clinical trials of apomorphine SL
    • HEATON JLM: Key issues from the clinical trials of apomorphine SL. World J. Urol. (2001) 19:25-31.
    • (2001) World J. Urol. , vol.19 , pp. 25-31
    • Heaton, J.L.M.1
  • 15
    • 0036755003 scopus 로고    scopus 로고
    • Phosphodiesterase type 5 as a pharmacologic target in erectile dysfunction
    • CORBIN JD, FRANCIS SH, WEBB DJ: Phosphodiesterase type 5 as a pharmacologic target in erectile dysfunction. Urology (2002) 60(Suppl. 2B):4-11.
    • (2002) Urology , vol.60 , Issue.SUPPL. 2B , pp. 4-11
    • Corbin, J.D.1    Francis, S.H.2    Webb, D.J.3
  • 17
    • 0032502708 scopus 로고    scopus 로고
    • Sildenafil: A novel inhibitor of phosphodiesterase type 5 in human corpus cavernosum smooth muscle cells
    • MORELAND RB, GOLDSTEIN I, TRAISH A: Sildenafil: a novel inhibitor of phosphodiesterase type 5 in human corpus cavernosum smooth muscle cells. Life Sci. (1998) 62:PL309-PL318.
    • (1998) Life Sci. , vol.62
    • Moreland, R.B.1    Goldstein, I.2    Traish, A.3
  • 18
    • 0032516296 scopus 로고    scopus 로고
    • Oral sildenafil in the treatment of erectile dysfunction
    • GOLDSTEIN I, LUE T, PADMA-NATHAN H et al.: Oral sildenafil in the treatment of erectile dysfunction. N. Engl. J. Med. (1998) 338:1397-1404.
    • (1998) N. Engl. J. Med. , vol.338 , pp. 1397-1404
    • Goldstein, I.1    Lue, T.2    Padma-Nathan, H.3
  • 19
    • 0344625866 scopus 로고    scopus 로고
    • Efficacy and safety of oral sildenafil and the treatment of erectile dysfunction: A double blind placebo controlled study of 329 patients
    • PADMA-NATHAN H, STEERS WD, WICKER PA: Efficacy and safety of oral sildenafil and the treatment of erectile dysfunction: a double blind placebo controlled study of 329 patients. Int. J. Clin. Prac. (1998) 53:1-4.
    • (1998) Int. J. Clin. Prac. , vol.53 , pp. 1-4
    • Padma-nathan, H.1    Steers, W.D.2    Wicker, P.A.3
  • 20
    • 0036121963 scopus 로고    scopus 로고
    • Pharmacogenetics of sildenafil after single oral doses in healthy male subjects: Absolue bioavailability, food effects, and dose proportionality
    • NICHOLS DJ, MUIRHEAD GJ, HARNESS JA. Pharmacogenetics of sildenafil after single oral doses in healthy male subjects: absolue bioavailability, food effects, and dose proportionality. Br. J. Clin. Pharmacol. (2002) 53:5S-12S.
    • (2002) Br. J. Clin. Pharmacol. , vol.53
    • Nichols, D.J.1    Muirhead, G.J.2    Harness, J.A.3
  • 21
    • 0033058382 scopus 로고    scopus 로고
    • Pharmacokinetics and metabolism of sildenafil in mouse, rat, rabbit, dog, and man
    • WALKER DK, ACKLAND MJ, JAMES GC et al.: Pharmacokinetics and metabolism of sildenafil in mouse, rat, rabbit, dog, and man. Xenobiotica (1999) 29:297-310.
    • (1999) Xenobiotica , vol.29 , pp. 297-310
    • Walker, D.K.1    Ackland, M.J.2    James, G.C.3
  • 22
    • 0001221211 scopus 로고    scopus 로고
    • Pharmacokinetics of sildenafil, a selective cGMP PDE 5 inhibitor, after single oral doses in fasted and fed healthy volunteers
    • MUIRHEAD GJ, ALLEN MJ, JAMES GC et al.: Pharmacokinetics of sildenafil, a selective cGMP PDE 5 inhibitor, after single oral doses in fasted and fed healthy volunteers. Br. J. Clin. Pharmacol. (1996) 42:268P.
    • (1996) Br. J. Clin. Pharmacol. , vol.42
    • Muirhead, G.J.1    Allen, M.J.2    James, G.C.3
  • 23
    • 0036118848 scopus 로고    scopus 로고
    • Comparative human pharmacokinetics and metabolism of a single dose oral and intravenous sildenafil citrate
    • MUIRHEAD GJ, RONCE DJ, WALKER DK, WASTOLL P: Comparative human pharmacokinetics and metabolism of a single dose oral and intravenous sildenafil citrate. J. Clin. Pharm. (2002) 53(Suppl.):135-215.
    • (2002) J. Clin. Pharm. , vol.53 , Issue.SUPPL. , pp. 135-215
    • Muirhead, G.J.1    Ronce, D.J.2    Walker, D.K.3    Wastoll, P.4
  • 24
    • 0035032248 scopus 로고    scopus 로고
    • Phosphodiesterase 5 inhibition effects on the coronary vasculature
    • JACKSON G: Phosphodiesterase 5 inhibition effects on the coronary vasculature. Int. J. Clin. Pract. (2001) 55:183-188.
    • (2001) Int. J. Clin. Pract. , vol.55 , pp. 183-188
    • Jackson, G.1
  • 26
    • 0037152092 scopus 로고    scopus 로고
    • Sildenafil for treatment of lung fibrosis in pulmonary hypertension: A randomized controlled trial
    • GHOFRANI HA, WIEDEMANN R, ROSE F et al.: Sildenafil for treatment of lung fibrosis in pulmonary hypertension: a randomized controlled trial. Lancet (2002) 360:895-900.
    • (2002) Lancet , vol.360 , pp. 895-900
    • Ghofrani, H.A.1    Wiedemann, R.2    Rose, F.3
  • 27
    • 0033522211 scopus 로고    scopus 로고
    • Tissue distribution of phosphodiesterase families and the effects of sildenafil on tissues cyclic nucleotides, platelet function in the contractile responses of trabeculate carneae in aortic rings in vitro
    • WALLIS RM, CORBIN JD, FRANCIS SH, ELLIS P: Tissue distribution of phosphodiesterase families and the effects of sildenafil on tissues cyclic nucleotides, platelet function in the contractile responses of trabeculate carneae in aortic rings in vitro. Am. J. Cardiol. (1999) 83(5A):3C-12C.
    • (1999) Am. J. Cardiol. , vol.83 , Issue.5 A
    • Wallis, R.M.1    Corbin, J.D.2    Francis, S.H.3    Ellis, P.4
  • 28
    • 0034213608 scopus 로고    scopus 로고
    • Hemodynamic effects of sildenafil in men with severe coronary artery disease
    • HERMANN HC, CHANG G, KLUGHERZ BD et al.: Hemodynamic effects of sildenafil in men with severe coronary artery disease. N. Engl. J. Med. (2000) 342:1622-1626.
    • (2000) N. Engl. J. Med. , vol.342 , pp. 1622-1626
    • Hermann, H.C.1    Chang, G.2    Klugherz, B.D.3
  • 29
    • 0033522152 scopus 로고    scopus 로고
    • Effects of sildenafil citrate on human hemodynamics
    • JACKSON G, BENJAMIN N, JACKSON N et al.: Effects of sildenafil citrate on human hemodynamics. Am. J. Cardiol. (1999) 83(Suppl. 5A):13C-20C.
    • (1999) Am. J. Cardiol. , vol.83 , Issue.SUPPL. 5A
    • Jackson, G.1    Benjamin, N.2    Jackson, N.3
  • 30
    • 0000303815 scopus 로고    scopus 로고
    • The effects of sildenafil citrate on color discrimination in volunteers and patients with erectile dysfunction
    • LATIES A, ELLIS P, MOLLON JD: The effects of sildenafil citrate on color discrimination in volunteers and patients with erectile dysfunction. Invest. Ophthalmol. Vis. Sci. (1999) 40:S693.
    • (1999) Invest. Ophthalmol. Vis. Sci. , vol.40
    • Laties, A.1    Ellis, P.2    Mollon, J.D.3
  • 31
    • 0036122678 scopus 로고    scopus 로고
    • The effects of age and renal and hepatic impairment on the pharmacokinetics of sildenafil citrate
    • MUIRHEAD GJ, WILNER K, COLBURN W et al.: The effects of age and renal and hepatic impairment on the pharmacokinetics of sildenafil citrate. Br. J. Pharmacol. (2002) 53:215-305.
    • (2002) Br. J. Pharmacol. , vol.53 , pp. 215-305
    • Muirhead, G.J.1    Wilner, K.2    Colburn, W.3
  • 32
    • 0037067992 scopus 로고    scopus 로고
    • Effects of two selective phosphodiesterase type 5 inhibitors, sildenafil and vardenafil, on object recognition memory and hippocampal cyclic GMP levels in the rat
    • PRICKAERTS J, VAN STAVERN WC, SIK A et al.: Effects of two selective phosphodiesterase type 5 inhibitors, sildenafil and vardenafil, on object recognition memory and hippocampal cyclic GMP levels in the rat. Neuroscience (2002) 113(2):351-361.
    • (2002) Neuroscience , vol.113 , Issue.2 , pp. 351-361
    • Prickaerts, J.1    Van Stavern, W.C.2    Sik, A.3
  • 33
    • 0036350615 scopus 로고    scopus 로고
    • Sildenafil induces powerful cardio protective effect via opening of mitochondrial K(ATP) channels in rabbits
    • OCKAILI R, SALLOUM F, HAWKINS J et al.: Sildenafil induces powerful cardio protective effect via opening of mitochondrial K(ATP) channels in rabbits. Am. J. Physiol. Heart Circ. Physiol. (2002) 283:H1263-H1269.
    • (2002) Am. J. Physiol. Heart Circ. Physiol. , vol.283
    • Ockaili, R.1    Salloum, F.2    Hawkins, J.3
  • 34
    • 0036755020 scopus 로고    scopus 로고
    • The efficacy of sildenafil citrate (Viagra) in clinical populations: An update
    • CARSON CC, BURNETT AL, LEVINE LA, NEHRA A: The efficacy of sildenafil citrate (Viagra) in clinical populations: an update. Urology (2002) 60(Suppl. 2B):12-27.
    • (2002) Urology , vol.60 , Issue.SUPPL. 2B , pp. 12-27
    • Carson, C.C.1    Burnett, A.L.2    Levine, L.A.3    Nehra, A.4
  • 35
    • 0030154874 scopus 로고    scopus 로고
    • Sildenafil: An orally active type 5 cyclic GMP specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction
    • BOOLELL M, ALLEN MJ, BALLARD SA et al.: Sildenafil: an orally active type 5 cyclic GMP specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction. Int. J. Impot. Res. (1996) 8:47-52.
    • (1996) Int. J. Impot. Res. , vol.8 , pp. 47-52
    • Boolell, M.1    Allen, M.J.2    Ballard, S.A.3
  • 36
    • 0036755170 scopus 로고    scopus 로고
    • A four year update on the safety of sildenafil
    • PADMA-NATHAN h, EARDLEY I, KLONER RA et al.: A four year update on the safety of sildenafil. Urology (2002) 60(Suppl. 2B):67-90.
    • (2002) Urology , vol.60 , Issue.SUPPL. 2B , pp. 67-90
    • Padma-Nathan, H.1    Eardley, I.2    Kloner, R.A.3
  • 37
    • 0031861609 scopus 로고    scopus 로고
    • Clinical safety of oral sildenafil citrate in the treatment of erectile dysfunction
    • MORALES A, GINGELL C, COLLINS M et al.: Clinical safety of oral sildenafil citrate in the treatment of erectile dysfunction. Int. J. Impot. Res. (1998) 10:69-74.
    • (1998) Int. J. Impot. Res. , vol.10 , pp. 69-74
    • Morales, A.1    Gingell, C.2    Collins, M.3
  • 38
    • 0345056314 scopus 로고    scopus 로고
    • Sildenafil citrate treatment for erectile dysfunction: Rate of adverse events decreases with time
    • CARSON CC, SIEGEL RL, ORAZEM J: Sildenafil citrate treatment for erectile dysfunction: rate of adverse events decreases with time. J. Urol. (2002) 167(Suppl.):179.
    • (2002) J. Urol. , vol.167 , Issue.SUPPL. , pp. 179
    • Carson, C.C.1    Siegel, R.L.2    Orazem, J.3
  • 39
    • 0032617617 scopus 로고    scopus 로고
    • ACC/AHA expert consensus document. Use of sildenafil (Viagra) in patients with cardiovascular disease
    • American College of Cardiology/American Heart Association
    • CHEITLIN MD, HUTTER AM Jr, BRINDIS RG et al.: ACC/AHA expert consensus document. Use of sildenafil (Viagra) in patients with cardiovascular disease. American College of Cardiology/American Heart Association. J. Am. Coll. Cardiol. (1999) 33:273-283.
    • (1999) J. Am. Coll. Cardiol. , vol.33 , pp. 273-283
    • Cheitlin, M.D.1    Hutter A.M., Jr.2    Brindis, R.G.3
  • 40
    • 0036754094 scopus 로고    scopus 로고
    • Achieving treatment optimization with sildenafil citrate in patients with erectile dysfunction
    • MCCULLOUGH AR, BARADA JH, FAWZY A et al.: Achieving treatment optimization with sildenafil citrate in patients with erectile dysfunction. Urology (2002) 60(Suppl. 2B):28-38.
    • (2002) Urology , vol.60 , Issue.SUPPL. 2B , pp. 28-38
    • Mccullough, A.R.1    Barada, J.H.2    Fawzy, A.3
  • 41
    • 0030926566 scopus 로고    scopus 로고
    • The International Index for Erectile Function (IIEF): A multidimensional scale for assessment of erectile function
    • ROSEN RC, RILEY A, WAGNER G et al.: The International Index for Erectile Function (IIEF): a multidimensional scale for assessment of erectile function. Urology (1997) 49:822-830.
    • (1997) Urology , vol.49 , pp. 822-830
    • Rosen, R.C.1    Riley, A.2    Wagner, G.3
  • 42
    • 0032860673 scopus 로고    scopus 로고
    • Clinical efficacy of sildenafil citrate based on etiology and response to prior treatment
    • JAROW JP, BURNETT AL, GERINGER AM: Clinical efficacy of sildenafil citrate based on etiology and response to prior treatment. J. Urol. (1999) 162:722-725.
    • (1999) J. Urol. , vol.162 , pp. 722-725
    • Jarow, J.P.1    Burnett, A.L.2    Geringer, A.M.3
  • 43
    • 0036754080 scopus 로고    scopus 로고
    • Efficacy and safety of sildenafil citrate in men with erectile dysfunction and spinal cord injury: A review
    • DERRY F, HULTLING C, SEFATEL AD et al.: Efficacy and safety of sildenafil citrate in men with erectile dysfunction and spinal cord injury: a review. Urology (2002) 60(Suppl. 2B):49-57.
    • (2002) Urology , vol.60 , Issue.SUPPL. 2B , pp. 49-57
    • Derry, F.1    Hultling, C.2    Sefatel, A.D.3
  • 44
    • 0036754975 scopus 로고    scopus 로고
    • Efficacy and safety of sildenafil in Black and Hispanic American men
    • YOUNG JM, BENNETT C, GILHOOLY P et al.: Efficacy and safety of sildenafil in Black and Hispanic American men. Urology (2002) 60(Suppl. 2B):39-48.
    • (2002) Urology , vol.60 , Issue.SUPPL. 2B , pp. 39-48
    • Young, J.M.1    Bennett, C.2    Gilhooly, P.3
  • 45
    • 0036755157 scopus 로고    scopus 로고
    • Depression, anti-depressant therapy in erectile dysfunction: Clinical trials of sildenafil citrate in treated and untreated patients with depression
    • NURNBERG HG, SEIDMAN SN, GELENBERG AJ et al.: Depression, anti-depressant therapy in erectile dysfunction: clinical trials of sildenafil citrate in treated and untreated patients with depression. Urology (2002) 60(Suppl. 2B):58-66.
    • (2002) Urology , vol.60 , Issue.SUPPL. 2B , pp. 58-66
    • Nurnberg, H.G.1    Seidman, S.N.2    Gelenberg, A.J.3
  • 46
    • 0034884952 scopus 로고    scopus 로고
    • Long term efficacy of sildenafil and tachyphylaxis effect
    • EI GALLEY R, RUTLAND H, TALIC R et al.: Long term efficacy of sildenafil and tachyphylaxis effect. J. Urol. (2001) 166:927-931.
    • (2001) J. Urol. , vol.166 , pp. 927-931
    • Ei Galley, R.1    Rutland, H.2    Talic, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.