Does skin fibroblast radiosensitivity predict squamous cancer cell radiosensitivity of the same individual?

International Journal of Cancer

Volumn 103, Issue 6, 2003, Pages 784-788

  Haikonen, Johanna ^a   Rantanen, Virpi ^a,b   Pekkola, Kirsi ^a   Kulmala, Jarmo ^a   Grénman, Reidar ^a,c  

^a UNIVERSITY OF TURKU   (Finland)

^b TURKU CITY HOSPITAL   (Finland)

^c TURKU UNIVERSITY HOSPITAL   (Finland)

Author keywords

Clonogenic assay; Head and neck carcinoma; In vitro radiosensitivity; SCC; SF2; Skin fibroblasts

Indexed keywords

ADULT; AGED; ARTICLE; CANCER CELL CULTURE; CANCER RADIOTHERAPY; CELL TYPE; CLINICAL ARTICLE; CLONOGENIC ASSAY; FEMALE; HEAD AND NECK CANCER; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; PRIORITY JOURNAL; RADIATION DOSE; RADIOSENSITIVITY; SKIN FIBROBLAST; SQUAMOUS CELL CARCINOMA; TREATMENT OUTCOME;

ADULT; AGED; AGED, 80 AND OVER; AREA UNDER CURVE; CARCINOMA, SQUAMOUS CELL; CELL SURVIVAL; COLONY-FORMING UNITS ASSAY; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; FIBROBLASTS; HEAD AND NECK NEOPLASMS; HUMANS; MALE; MIDDLE AGED; RADIATION TOLERANCE; SKIN; TUMOR CELLS, CULTURED;

EID: 0037350216     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.10890     Document Type: Article

References (45)

1. Tucker SL, Turesson I, Thames HD. Evidence for individual differences in the radiosensitivity of human skin. Eur J Cancer 1992;28A:1783-91.
2. Turesson I, Nyman J, Holmberg E, Oden A. Prognostic factors for acute and late skin reactions in radiotherapy patients. Int J Radiat Oncol Biol Phys 1996;36:1065-75.
3. Peters LJ. Significance of genetic variability in radiosensitivity in clinical radiotherapy. J Jpn Soc Ther Radiol Oncol 1990;2:247-53.
4. Tucker SL, Geara FB, Peters LJ, Brock WA. How much could the radiotherapy dose be altered for individual patients based on a predictive assay of normal-tissue radiosensitivity? Radiother Oncol 1996; 38:103-13.
5. Burnet NG, Nyman J, Turesson I, Wurm R, Yarnold JR, Peacock JH. The relationship between cellular radiation sensitivity and tissue response may provide the basis for individualising radiotherapy schedules. Radiother Oncol 1994;33:228-38.
6. Geara FB, Peters LJ, Ang KK, Wike JL, Brock WA. Prospective comparison of in vitro normal cell radiosensitivity and normal tissue reactions in radiotherapy patients. Int J Radiat Oncol Biol Phys 1993;27:1173-9.
7. Johansen J, Bentzen SM, Overgaard J, Overgaard M. Evidence for a positive correlation between in vitro radiosensitivity of normal human skin fibroblasts and the occurrence of subcutaneous fibrosis after radiotherapy. Int J Radiat Biol 1994;66:407-12.
8. Johansen J, Bentzen SM, Overgaard J, Overgaard M. Relationship between the in vitro radiosensitivity of skin fibroblasts and the expression of subcutaneous fibrosis, telangiectasia, and skin erythema after radiotherapy. Radiother Oncol 1996;40:101-9.
9. Begg AC, Russell NS, Knaken H, Lebesque JV. Lack of correlation of human fibroblast radiosensitivity in vitro with early skin reactions in patients undergoing radiotherapy. Int J Radiat Biol 1993;64:393-405.
10. Brock WA, Tucker SL, Geara FB, Turesson I, Wike JL, Nyman J, Peters LJ. Fibroblast radiosensitivity versus acute and late normal skin responses in patients treated for breast cancer. Int J Radiat Oncol Biol Phys 1995;32:1371-9.
11. Rudat V, Dietz A, Conradt C, Weber K-J, Flentje M. In vitro radiosensitivity of primary human fibroblasts. Lack of correlation with acute radiation toxicity in patients with head and neck cancer. Radiother Oncol 1997;43:181-8.
12. Fertil B, Malaise E-P. Intrinsic radiosensitivity of human cell lines is correlated with radioresponsiveness of human tumors: analysis of 101 published survival curves. Int J Radiat Oncol Biol Phys 1985;11: 1699-707.
13. West CML, Davidson SE, Hendry JH, Hunter RD. Prediction of cervical carcinoma response to radiotherapy. Lancet 1991;338:818.
14. Stausbø-Grøn B, Overgaard J. Relationship between tumour cell in vitro radiosensitivity and clinical outcome after curative radiotherapy for squamous cell carcinomas of the head and neck. Radiother Oncol 1999;50:47-55.
15. Girinsky T, Bernheim A, Lubin R, Tavakoli-Razavi T, Baker F, Janot F, Wibault P, Cosset J-M, Duvillard P, Duverger A, Fertil B. In vitro parameters and treatment outcome in head and neck cancers treated with surgery and/or radiation: cell characterization and correlations with local control and overall survival. Int J Radiat Oncol Biol Phys 1994;30:789-94.
16. Björk-Eriksson T, West C, Karlsson E, Mercke C. Tumor radiosensitivity (SF2) is a prognostic factor for local control in head and neck cancers. Int J Radiat Oncol Biol Phys 2000;46:13-9.
17. Pekkola-Heino K, Servomaa K, Kiuru A, Grénman R. Sublethal damage repair capacity in carcinoma cell lines with p53 mutations. Head Neck 1998;20:298-303.
18. Landsford CD, Grénman R, Bier H, Somers KD, Kim S-Y, Whiteside TL, Clayman GL, Welkoborsky H-J, Carey TE. Head and neck cancers. In: Masters J, Palsson B. Human cell culture, vol. 2. Cancer cell lines part 2. Dordrecht, Holland: Kluwer Academic Press, 1999. 185-255.
19. Pekkola-Heino K, Servomaa K, Kiuru A, Grénman R. Increased radiosensitivity is associated with p53 mutations in cell lines derived from oral cavity carcinoma. Acta Otolaryngol 1996;116:341-4.
20. Pulkkinen J, Servomaa K, Pekkola K, Kulmala J, Grénman R. The effect of irradiation on mitotic and apoptotic frequency in head and neck cancer cell lines, the correlation to p53 mutations and clonogenic survival. Anticancer Res 2000;20:1503-12.
21. Honkanen J, Rantanen V, Kulmala J, Grénman R, Klemi P, Pekkola-Heino K. Radiosensitivity of dermal and tumor fibroblasts derived from the same patient. J Cancer Res Clin Oncol 1998;124:415-20.
22. Grénman R, Carey TE, McClatchey KD, Wagner JG, Pekkola-Heino K, Schwarz DR, Wolf GT, Lacivita LP, Ho L, Baker SR, Krause CJ, Lichter AS. In vitro radiation resistance among cell lines established from patients with squamous cell carcinoma of the head and neck. Cancer 1991;67:2741-7.
23. Grénman R, Burk D, Virolainen E, Buick R, Church J, Schwartz DR, Carey TE. Clonogenic cell assay for anchorage-dependent squamous carcinoma cell lines using limiting dilution. Int J Cancer 1989;44: 131-6.
24. Kulmala J, Rantanen V, Pekkola-Heino K, Tuominen J, Grénman R. Dosimetry of irradiation models: the 96-well clonogenic assay for testing radiosensitivity of cell lines. Acta Oncol 1995;34:105-9.
25. Thilly WG, DeLuca JG, Furth EE, Hoppe H, Kaden DA, Krolenski JJ, Liber HL, Skopek TR, Slapikoff SA, Tizard RJ, Penman BW. Genelocus mutation assays in diploid human lymphoblast lines. In: De Serpes FJ, Hollaender A. Chemical mutagens. New York: Plenum Publishing, 1980. 331-64.
26. Girinsky T, Lubin R, Pignon JP, Chavaudra N, Gazeau J, Dubray B, Cosset JM, Socie G, Fertil B. Predictive value of in vitro radiosensitivity parameters in head and neck cancers and cervical carcinomas: preliminary correlations with local control and overall survival. Int J Radiat Oncol Biol Phys 1992;25:3-7.
27. Brock WA, Baker FL, Peters LJ. Radiosensitivity of human head and neck squamous cell carcinomas in primary culture and its potential as a predictive assay of tumor radiocurability. Int J Radiat Biol 1989; 56:751-60.
28. Brock WA, Baker FL, Wike JL, Sivon SL, Peters LJ. Cellular radiosensitivity of primary head and neck squamous cell carcinomas and local tumor control. Int J Radiat Oncol Biol Phys 1990;18:1283-6.
29. Stausbøl-Grøn B, Nielsen OS, Bentzen SM, Overgaard J. Selective assessment of in vitro radiosensitivity of tumour cells and fibroblasts from single turnout biopsies using immunocytochemical identification of colonies in the soft agar clonogenic assay. Radiother Oncol 1995; 37:87-99.
30. Stausbøl-Grøn B, Bentzen SM, Jørgensen KE, Nielsen OS, Bundgaard T, Overgaard J. In vitro radiosensitivity of turnout cells and fibroblasts derived from head and neck carcinomas: mutual relationship and correlation with clinical data. Br J Cancer 1999;79: 1074-84.
31. West CML, Davidson SE, Hunter RD. Evaluation of surviving fraction at 2 Gy as a potential prognostic factor for the radiotherapy of carcinoma of the cervix. Int J Radiat Biol 1989;56:761-5.
32. West CML, Davidson SE, Burt PA, Hunter RD. The intrinsic radiosensitivity of cervical carcinoma: correlations with clinical data. Int J Radiat Oncol Biol Phys 1995;31:841-6.
33. Malaise E-P, Fertil B, Deschavanne PJ, Chavaudra N, Brock WA. Initial slope of radiation survival curves is characteristic of the origin of primary and established cultures of human tumor cells and fibroblasts. Radiat Res 1987;111:319-33.
34. Weichselbaum RR, Rotmensch J, Ahmed-Swan S, Beckett MA. Radiobiological characterization of 53 human tumor cell lines. Int J Radiat Biol 1989;56:553-60.
35. Dahlberg WK, Little JB, Flecher JA, Suit HD, Okunieff P. Radiosensitivity in vitro of human soft tissue sarcoma cell lines and skin fibroblasts derived from the same patients. Int J Radiat Biol 1993;63: 191-8.
36. Geara FB, Peters LJ, Ang KK, Wike JL, Sivon SL, Guttenberger R, Callender DL, Malaise E-P, Brock WA. Intrinsic radiosensitivity of normal human fibroblasts and lymphocytes after high- and low-doserate irradiation. Cancer Res 1992;52:6348-52.
37. Geara FB, Peters LJ, Ang KK, Wike JL, Brock WA. Radiosensitivity measurement of keratinocytes and fibroblasts from radiotherapy patients. Int J Radiat Oncol Biol Phys 1992;24:287-93.
38. Sugimoto M, Toguchida J, Kotoura Y, Yamamuro T, Utsumi H. Intrinsic radiosensitivity and PLD repair in osteosarcoma cell lines. Int J Radiat Biol 1992;62:469-74.
39. Wurm R, Burnet NG, Duggal N, Yarnold JR, Peacock JH. Cellular radiosensitivity and DNA damage in primary human fibroblasts. Int J Radiat Oncol Biol Phys 1994;30:625-33.
40. Allalunis-Turner MJ, Barron GM, Day RS, Fulton DS, Urtasun RC. Radiosensitivity testing of human primary brain tumor specimens. Int J Radiat Oncol Biol Phys 1992;23:339-43.
41. Fertil B, Malaise E-P. Inherent cellular radiosensitivity as a basic concept for human tumor radiotherapy. Int J Radiat Oncol Biol Phys 1981;7:621-9.
42. Stausbøl-Grøn B, Bentzen SM, Overgaard J. Characterization and radiosensitivity of fibroblasts derived from squamous cell carcinomas of the head and neck, and the surrounding oral mucosa. Acta Oncol 1998;37:697-700.
43. Mackay RI, Hendry JH. The modelled benefits of individualizing radiotherapy patients' dose using cellular radiosensitivity assays with inherent variability. Radiother Oncol 1999;50:67-75.
44. Geara FB, Peters LJ, Ang KK, Garden AS, Tucker SL, Levy LB, Brown BW. Comparison between normal tissue reactions and local tumor control in head and neck cancer patients treated by definitive radiotherapy. Int J Radiat Oncol Biol Phys 1996;35:455-62.
45. Sobin LH, Wittekind C. TNM classification of malignant turnouts, 5th ed. New York: John Wiley & Sons Inc., 1997.