Comparison between normal tissue reactions and local tumor control in head and neck cancer patients treated by definitive radiotherapy

International Journal of Radiation Oncology Biology Physics

Volumn 35, Issue 3, 1996, Pages 455-462

  Geara, Fady B ^a,b   Peters, Lester J ^a   Ang, K Kian ^a   Garden, Adam S ^a   Tucker, Susan L ^a   Levy, Lawrence B ^a   Brown, Barry W ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Head and neck cancer; Normal tissue reactions; Tumor response

Indexed keywords

ADULT; AGED; ARTICLE; CANCER CONTROL; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER STAGING; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HEAD AND NECK CANCER; HUMAN; MAJOR CLINICAL STUDY; MALE; MUCOSA INFLAMMATION; PRIORITY JOURNAL; RADIATION DOSE FRACTIONATION; RADIOSENSITIVITY; TISSUE REACTION; TREATMENT FAILURE;

EID: 0030175642     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(96)80006-X     Document Type: Article

References (53)

1. 1. Abadir, R.; Hakami, N. Ataxia telangiectasia with cancer. An indication for reduced radiotherapy and chemotherapy doses. Br. J. Radiol. 56:343-345; 1983.
2. 2. Ang, K. K.; Peters, L. J.; Weber, R. S.; Maor, M. H.; Morrison, W. H.; Wendt, C. D.; Brown, B. W. Concomitant boost radiotherapy schedules in the treatment of carcinoma of the oropharynx and nasopharynx. Int. J. Radiat. Oncol. Biol. Phys. 19:1339-1345; 1990.
3. 3. Barcellos-Hoff, M. H. Radiation-induced transforming growth factor b and subsequent extracellular matrix reorganization in murine mammary gland. Cancer Res. 53:3880-3886; 1993.
4. 4. Begg, A. C.; Russell, N. S.; Knaken, H.; Lebesque, J. V. Lack of correlation of human fibroblast radiosensitivity in vitro with early skin reactions in patients undergoing radiotherapy. Int. J. Radiat. Biol. 64:393-405; 1993.
5. 5. Bentzen, S. M.; Overgaard, M.; Overgaard, J. Clinical correlations between late normal tissue endpoints after radiotherapy: Implications for predictive assays of radiosensitivity. Eur. J. Cancer 29:1373-1376; 1993.
6. 6. Border, W. A.; Noble, N. A. Transforming growth factor b in tissue fibrosis. N. Engl. J. Med. 331:1286-1292; 1994.
7. 7. Bristow, R. G.; Jang, A.; Peacock, J.; Chung, S.; Benchimol, S.; Hill, R. P. Mutant p53 increases radioresistance in rat embryo fibroblasts simultaneously transfected with HPV16-E7 and/or activated H-ras. Oncogene 9:1527-1536; 1994.
8. 8. Brock, W. A.; Baker, F. L.; Wike, J. L.; Sivon, S. L.; Peters, L. J. Cellular radiosensitivity of primary head and neck squamous cell carcinomas and local tumor control. Int. J. Radiat. Oncol. Biol. Phys. 18:1283-1286; 1990.
9. 9. Brock, W. A.; Tucker, S. L.; Geara, F. B.; Turesson, I.; Wike, J.; Nyman, J.; Peters, L. J. Fibroblast radiosensitivity versus acute and late normal skin responses in patients treated for breast cancer. Int. J. Radiat. Oncol. Biol. Phys. 32:1371-1379; 1995.
10. 10. Budach, W.; Hartford, A.; Gioioso, D.; Freeman, J.; Taghian, A.; Suit, H. D. Tumors arising in SCID mice share enchanced radiation sensitivity of SCID normal tissues. Cancer Res. 52:6292-6292; 1992.
11. 11. Burnet, N. G.; Nyman, J.; Turesson, I.; Wurm, R.; Yarnold, J. R.; Peacock, J. H. Prediction of normal-tissue tolerance to radiotherapy from in vitro cellular radiation sensitivity. Lancet 339:1570-1571; 1992.
12. 12. Cheong, N.; Wang, Y.; Iliakis, G. Radioresistance induced in rat embryo cells by transfection with the oncogenes H-ras plus v-myc is cell cycle dependent and maximal during S and G2, Int. J. Radiat. Biol. 3:623-629; 1993.
13. 13. Coutard, H. Roentgentherapy of epitheliomas of the tonsillar region, hypopharynx and larynx from 1920-1926. Am. J. Roentgenol. 28:313-323; 1932.
14. 14. Dahlberg, W. K.; Little, J. B.; Fletcher, J. A.; Suit, H. D.; Okunieff, P. Radiosensitivity in vitro of human soft tissue sarcoma cell lines and skin fibroblasts derived from the same patients. Int. J. Radiat. Biol. Phys. 63:191-198; 1993.
15. 15. Deacon, J.; Peckham, M. J.; Steel, G. G. The radioresposivmess of human tumors and the initial slope of the cell survival curve. Radiother. Oncol. 2:317-323; 1984.
16. 16. Deschavanne, P. J.; Debieu, D.; Fertil, B.; Malaise, E. P. Reevaluation of in vitro radiosensitivity of human fibroblasts of different genetic origins. Int. J. Radiat. Biol. 50:279-293; 1986.
17. 17. El Nabout, R.; Martin, M.; Remy, J.; Kern, P.; Robert, L.; Lafuma, C. Collagen synthesis and deposition in cultured fiboblasts from SC radiation-induced fibrosis. Modification as a function of cell aging. Matrix 9:441-420; 1989.
18. 18. Fertil, B.; Malaise, E. P. Inherent cellular radiosensitivity as a basic concept for human tumor radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 7:1127-1134; 1981.
19. 19. Garden, A. S.; Morrison, W. H.; Ang, K. K.; Peters, L. J. Hyperfractionated radiation in the treatment of squamous cell carcinomas of the head and neck: A comparison of two fractionation schedules. Int. J. Radiat. Oncol. Biol. Phys. 31:493-502; 1995.
20. 20. Geara, F. B.; Peters, L. J.; Ang, K. K.; Wike, J. L.; Brock, W. A. Radiosensitivity measurement of keratinocytes and fibroblasts from radiotherapy patients. Int. J. Radiat. Oncol. Biol. Phys. 24:287-293; 1992.
21. 21. Geara, F. B.; Peters, L. J.; Ang, K. K.; Wike, J. L.; Brock, W. A. Prospective comparison between in vitro normal cell radiosensitivity and normal tissue reactions in radiotherapy patients. Int. J. Radiat. Oncol. Biol. Phys. 27:1173-1179; 1993.
22. 22. Geara, F. B.; Peters, L. J.; Ang, K. K.; Wike, J. L.; Sivon, S.; Guttenburger, R.; Callender, D.; Malaise, E. P.; Brock, W. A. Intrinsic radiosensitivity of human fibroblasts and lymphocytes after high-and low-dose rate irradiations. Cancer Res. 52:6348-6352; 1992.
23. 23. Gentner, N. E.; Morrison, D. P.; Myers, D. K. Impact on radiogenic cancer risk of persons exhibiting abnormal sensitivity to ionizing radiation. Health Phys. 55:415-425; 1988.
24. 24. Green, M. H. L.; Arlett, C. F.; Cole, J.; Harcourt, S. A.; Priestley, A.; Waugh, A. P. W.; Stephens, G.; Beare, D. M.; Brown, N. A. P.; Shun-shin, G. A. Comparative human cellular radiosensitivity: III. Gamma-radiation survival of cultured skin fibroblasts and resting T-lymphocytes from the peripheral blood of the same individual. Int. J. Radiat. Biol. 59:749-765; 1991.
25. 25. Hart, R. M.; Kilmer, B. F.; Evans, R. G.; Park, C. H. Radiotherapeutic management of medulloblastoma in a pediatric patient with telangiectasia. Int. J. Radiat. Oncol. Biol. Phys. 13:1237-1240; 1987.
26. 26. Horiot, J. C.; LeFur, R.; Schraub, S.; Van Den Bogaert, W.; Van Glabbeke, M.; Pierart, M.; Begg, A. C. Status of the experience of the EORTC cooperative group of radiotherapy with hyperfractionated and accelerated radiotherapy regimes. Semin. Radiat. Oncol. 2:34-37; 1992.
27. 27. Horiot, J. C.; Nabid, A.; Chaplain, G. Clinical experience with multiple fractions per day (MFD) in the radiotherapy of head and neck carcinoma. J. Eur. Radiothèr. 3:79-89; 1982.
28. 28. Hsu, T. C.; Shillitoe, E. J.; Cherry, L. M.; Lin, Q.; Schantz, S. P.; Furlong, C. Cytogenetic characterization of 20 lymphoblastoid lines derived from human individuals differing in bleomycin sensitivity. In Vitro Cell. Dev. Biol. 26:80-84; 1990.
29. 29. Johansen, J.; Bentzen, S. M.; Overgaard, J; Overgaard, M. Evidence for a positive correlation between in vitro radiosensitivity of normal human skin fibroblasts and the occurrence of SC fibrosis after radiotherapy. Int. J. Radiat. Biol. 66:407-412; 1994.
30. 30. Kushiro, J. I.; Nakamura, N.; Kyoizumi, S.; Nishiki, M.; Dohi, K.; Akiyama, M. Absence of correlations between radiosensitivities of human T-lymphocytes in G0 and skin fibroblasts in log phase. Radiat. Res. 122:326-332; 1990.
31. 31. Little, J. B.; Nove, J. Sensitivity of human diploid fibroblast cell strains from various genetic disorders to acute and protracted radiation exposure. Radiat. Res. 123:87-92; 1990.
32. 32. Little, J. B.; Nove, J.; Strong, L. C. Survival of human diploid skin fibroblasts from normal individuals after X-irradiation. Int. J. Radiat. Biol. 54:899-910; 1988.
33. 33. Maciejewski, B.; Withers, H. R.; Taylor, J. M.; Hliniak, A. Dose fractionation and regeneration in radiotherapy for cancer of the oral cavity and oropharynx. Part 2. Normal tissue responses: Acute and late effects. Int. J. Radiat. Oncol. Biol. Phys. 18:101-111; 1990.
34. 34. Malaise, E. P.; Fertil, B.; Deschavanne, P. J.; Chavaudra, N.; Brock, W. A. Initial slope of radiation survival curves is characteristic of the origin of primary and established cultures of human tumor cells and fibroblasts. Radiat. Res. 111:319-333; 1987.
35. 35. Marcial, V. A.; Pajak, T. F.; Chang, C.; Tupchong, L.; Stetz, J. Hyperfractionated photon radiation therapy in the treatment of advanced squamous cell carcinoma of the oral cavity, pharynx, larynx, and sinuses, using radiation therapy as the only planned modality: (Preliminary report) by the Radiation Therapy Oncology Group (RTOG). Int. J. Radiat. Oncol. Biol. Phys. 13:41-47; 1987.
36. 36. Martin, M.; Remy, J.; Daburon, F. In vitro growth potential of fibroblasts isolated from pigs with radiation-induced dibrosis. Int. J. Radiat. Biol. Phys. 49:821-828; 1986.
37. 37. McIlwrath, A. J.; Vasey, P. A.; Ross, G. M.; Brown, R. Cell cycle arrests and radiosensitivity of human tumor cell lines: Dependence on wild-type p53 for radiosensitivity. Cancer Res. 54:3718-3722; 1994.
38. 38. Pandita, T. K.; Hittelman, W. N. Initial chromosome damage but not DNA damage is greater in ataxia telangiectasia cells. Radiat. Res. 130:94-103; 1992.
39. 39. Peters, L. J. Regaud Lecture: Inherent radiosensitivity of tumor and normal tissue cells as a predictor of human tumor response. Radiother. Oncol. 17:177-190; 1990.
40. 40. Peters, L. J. Janeway Lecture: Radiation therapy tolerance limits: For one or for all. Cancer; in press: 1995.
41. 41. Peters, L. J.; Brock, W. A.; Chapman, J. D.; Wilson, G. Predictive assays of tumor radiocurability. Am. J. Clin. Oncol. 11:275-287; 1988.
42. 42. Peters, L. J.; Harrison, M. L.; Dimery, I. W.; Fields, R.; Goepfert, H.; Oswald, M. J. Acute and late toxicity associated with sequential bleomycin-containing chemotherapy regimens and radiation therapy in the treatment of carcinoma of the nasopharynx. Int. J. Radiat. Oncol. Biol. Phys. 14:623-633; 1988.
43. 43. Ramsay, J.; Birrell, G. Normal tissue radiosensitivity in breast cancer patients. Int. J. Radiat. Oncol. Biol. Phys. 31:339-344; 1995.
44. 44. Remy, J.; Wedgrowski, J.; Crechet, F.; Martin, M.; Daburon, F. Long-term overproduction of collagen in radiation-induced fibrosis. Radiat. Res. 125:14-19; 1991.
45. 45. Rubin, P.; Finkelstein, J.; Shapiro, D. Molecular biology mechanisms in the radiation induction of pulmonary injury syndromes: Interrelationship between the alveolar macrophase and the septal fibroblast. Int. J. Radiat. Oncol. Biol. Phys. 24:93-101; 1992.
46. 46. Sailer, S. L.; Weissler, M. C.; Melin, S. A.; Qaqish, B. F.; Hoyle, D.; Rosenman, J. G.; Pillsbury, H. C. Toxicity and preliminary results from a trial of hyperfractionated radiation with or without simultaneous 5-fluorouracil-cisplatin in advanced head and neck squamous celt carcinomas. Semin. Radiat. Oncol. 2:38-40; 1992.
47. 47. Taghian, A.; Ramsay, J.; Allalunis-Turner, J.; Budach, W.; Gioioso, D.; Pardo, F.; Okunieff, P.; Bleehen, N.; Urtasun, R.; Suit, H. Intrinsic radiation sensitivity may not be the major determinant of the poor clinical outcome of glioblastoma multiforme. Int. J. Radiat. Oncol. Biol. Phys. 25:243-249; 1993.
48. 48. Trotti, A.; Klotch, D.; Endicott, J.; Ridley, M.; Greenberg, H. A prospective trial of accelerated radiotherapy in the postoperative treatment of high-risk squamous cell carcinoma of the head and neck. Int. J. Radiat. Oncol. Biol. Phys. 26:13-21; 1993.
49. 49. Tucker, S. L.; Turesson, I.; Thames, H. D. Evidence for individual differences in the radiosensitivity of human skin. Eur. J. Cancer 28A: 1783-1791; 1992.
50. 50. Turesson, I. Individual variation and dose dependency in the progression rate of skin telangiectasia. Int. J. Radiat. Oncol. Biol. Phys. 19:1569-1574; 1990.
51. 51. Wendt, C. D.; Peters, L. J.; Ang, K. K.; Morrison, W. H.; Maor, M. H.; Goepfert, M. D.; Oswald, M. J. Hyperfractionated radiotherapy in the treatment of squamous cell carcinomas of the supraglottic larynx. Int. J. Radiat. Oncol. Biol. Phys. 17:1057-1062; 1989.
52. 52. West, C. M.; Davidson, S. E.; Hunter, R. D. Evaluation of surviving fraction at 2 Gy as a potential prognostic factor for the radiotherapy of carcinoma of the cervix. Int. J. Radiat. Biol. 56:761-765; 1989.
53. 53. Wolf, G. T. The Department of Veterans Affairs Laryngeal Cancer Study Group: Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer. N. Engl. J. Med. 324:1685-1690; 1991.