In vivo blockade of platelet ADP receptor P2Y12 reduces embolus and thrombus formation but not thrombus stability

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 23, Issue 3, 2003, Pages 518-523

  Van Gestel, Miriam A ^a   Heemskerk, Johan W M ^a   Slaaf, Dick W ^a,b   Heijnen, Viviane V T ^a   Reneman, Robert S ^a   Oude Egbrink, Mirjam G A ^a,c  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b EINDHOVEN UNIVERSITY OF TECHNOLOGY   (Netherlands)

^c MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Adenosine diphosphate; Antithrombotic drugs; In vivo thromboembolism; Platelet activation; Vessel wall injury

Indexed keywords

6 N (2 METHYLTHIOETHYL) 2 (3,3,3 TRIFLUOROPROPYLTHIO)ADENOSINE PHOSPHATE; ADENOSINE DIPHOSPHATE; ANTICOAGULANT AGENT; CALCIUM ION; CLOPIDOGREL; PURINE P2Y RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; THROMBIN;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; BLOOD VESSEL INJURY; CONTROLLED STUDY; DRUG EFFICACY; EMBOLISM; FEMALE; ISCHEMIA; MALE; MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; RABBIT; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOEMBOLISM; THROMBUS;

ADENOSINE MONOPHOSPHATE; ADMINISTRATION, ORAL; ANIMALS; BLOOD PLATELETS; CALCIUM; FEMALE; MALE; MEMBRANE PROTEINS; PLATELET ACTIVATION; PLATELET AGGREGATION; RABBITS; RECEPTORS, PURINERGIC P2; THROMBIN; THROMBOEMBOLISM; TICLOPIDINE;

EID: 0037341392     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000057809.32354.22     Document Type: Article

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