Processing and presentation of the islet autoantigen GAD by vascular endothelial cells promotes transmigration of autoreactive T-cells

Diabetes

Volumn 52, Issue 3, 2003, Pages 717-725

  Greening, James E ^a,b   Tree, Timothy I M ^a   Kotowicz, Karolena T ^b   Van Halteren, Astrid G ^c   Roep, Bart O ^c   Klein, Nigel J ^b   Peakman, Mark ^a,d  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^d ST THOMAS HOSPITAL   (United Kingdom)

Author keywords

APC, antigen presenting cell; CFDA SE, carboxyfluorescein diacetate succidimidyl ester, EC, endothelial cell; CFDA SE, carboxyfluorescein diacetate succinimidyl ester, HBSS, Hank's balanced salt solution; EPV, Epstein Barr virus

Indexed keywords

AUTOANTIGEN; EPITOPE; GAD65 AUTOANTIGEN; GAMMA INTERFERON; HLA ANTIGEN CLASS 2; HLA DR ANTIGEN; HLA DR3 ANTIGEN; HLA DR4 ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ARTICLE; CELL INFILTRATION; CELL MIGRATION; CELL PROLIFERATION; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET CELL; PRIORITY JOURNAL; T LYMPHOCYTE;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGEN PRESENTATION; AORTA; AUTOANTIGENS; CELL MOVEMENT; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; FLOW CYTOMETRY; GENE EXPRESSION; GENOTYPE; GLUTAMATE DECARBOXYLASE; HISTOCOMPATIBILITY ANTIGENS CLASS II; HLA-DR ANTIGENS; HUMANS; HYBRIDOMAS; INTERFERON TYPE II; ISLETS OF LANGERHANS; ISOENZYMES; MICE; PEPTIDE FRAGMENTS; T-LYMPHOCYTES;

EID: 0037341332     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.52.3.717     Document Type: Article

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