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Volumn 12, Issue 5, 2003, Pages 535-549

Loss of imprinting of IGF2 and H19 in osteosarcoma is accompanied by reciprocal methylation changes of a CTCF-binding site

Author keywords

[No Author keywords available]

Indexed keywords

BISULFITE; SOMATOMEDIN B; TUMOR SUPPRESSOR PROTEIN; ZINC FINGER PROTEIN;

EID: 0037339969     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/ddg034     Document Type: Article
Times cited : (136)

References (43)
  • 1
    • 0025320906 scopus 로고
    • A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting
    • DeChiara, T.M., Efstratiadis, A. and Robertson, E.J. (1990) A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting. Nature, 345, 78-80.
    • (1990) Nature , vol.345 , pp. 78-80
    • DeChiara, T.M.1    Efstratiadis, A.2    Robertson, E.J.3
  • 4
    • 0026849544 scopus 로고
    • Monoallelic expression of the human H19 gene
    • Zhang, Y. and Tycko, B. (1992) Monoallelic expression of the human H19 gene. Nat. Genet., 1, 40-44.
    • (1992) Nat. Genet. , vol.1 , pp. 40-44
    • Zhang, Y.1    Tycko, B.2
  • 6
    • 0027285258 scopus 로고
    • Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour
    • Ogawa, O., Eccles, M.R., Szeto, J., McNoe, L.A., Yun, K., Maw, M.A., Smith, P.J. and Reeve, A.E. (1993) Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour. Nature, 362, 749-751.
    • (1993) Nature , vol.362 , pp. 749-751
    • Ogawa, O.1    Eccles, M.R.2    Szeto, J.3    McNoe, L.A.4    Yun, K.5    Maw, M.A.6    Smith, P.J.7    Reeve, A.E.8
  • 7
    • 0031761362 scopus 로고    scopus 로고
    • Loss of imprinting in normal tissue of colorectal cancer patients with microsatellite instability
    • Cui, H., Horon, I.L., Ohlsson, R., Hamilton, S.R. and Feinberg, A.P. (1998) Loss of imprinting in normal tissue of colorectal cancer patients with microsatellite instability. Nat. Med., 4, 1276-1280.
    • (1998) Nat. Med. , vol.4 , pp. 1276-1280
    • Cui, H.1    Horon, I.L.2    Ohlsson, R.3    Hamilton, S.R.4    Feinberg, A.P.5
  • 8
    • 0033539895 scopus 로고    scopus 로고
    • Relaxation of IGF2 imprinting in Wilms tumours associated with specific changes in IGF2 methylation
    • Sullivan, M.J., Taniguchi, T., Jhee, A., Kerr, N. and Reeve, A.E. (1999) Relaxation of IGF2 imprinting in Wilms tumours associated with specific changes in IGF2 methylation. Oncogene, 18, 7527-7534.
    • (1999) Oncogene , vol.18 , pp. 7527-7534
    • Sullivan, M.J.1    Taniguchi, T.2    Jhee, A.3    Kerr, N.4    Reeve, A.E.5
  • 9
    • 0034162161 scopus 로고    scopus 로고
    • Symmetric and asymmetric DNA methylation in the human IGF2-H19 imprinted region
    • Vu, T.H., Li, T., Nguyen, D., Nguyen, B.T., Yao, X.M., Hu, J.F. and Hoffman, A.R. (2000) Symmetric and asymmetric DNA methylation in the human IGF2-H19 imprinted region. Genomics, 64, 132-143.
    • (2000) Genomics , vol.64 , pp. 132-143
    • Vu, T.H.1    Li, T.2    Nguyen, D.3    Nguyen, B.T.4    Yao, X.M.5    Hu, J.F.6    Hoffman, A.R.7
  • 10
    • 0034713375 scopus 로고    scopus 로고
    • Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene
    • Bell, A.C. and Felsenfeld, G. (2000) Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene. Nature, 405, 482-485.
    • (2000) Nature , vol.405 , pp. 482-485
    • Bell, A.C.1    Felsenfeld, G.2
  • 11
    • 0034713275 scopus 로고    scopus 로고
    • CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus
    • Hark, A.T., Schoenherr, C.J., Katz, D.J., Ingram, R.S., Levorse, J.M. and Tilghman, S.M. (2000) CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus. Nature, 405, 486-489.
    • (2000) Nature , vol.405 , pp. 486-489
    • Hark, A.T.1    Schoenherr, C.J.2    Katz, D.J.3    Ingram, R.S.4    Levorse, J.M.5    Tilghman, S.M.6
  • 12
    • 0034193691 scopus 로고    scopus 로고
    • Maternal-specific footprints at putative CTCF sites in the H19 imprinting control region give evidence for insulator function
    • Szabo, P., Tang, S.H., Rentsendorj, A., Pfeifer, G.P. and Mann, J.R. (2000) Maternal-specific footprints at putative CTCF sites in the H19 imprinting control region give evidence for insulator function. Curr. Biol., 10, 607-610.
    • (2000) Curr. Biol. , vol.10 , pp. 607-610
    • Szabo, P.1    Tang, S.H.2    Rentsendorj, A.3    Pfeifer, G.P.4    Mann, J.R.5
  • 13
    • 0034644120 scopus 로고    scopus 로고
    • Functional association of CTCF with the insulator upstream of the H19 gene is parent of origin-specific and methylation-sensitive
    • Kanduri, C., Pant, V., Loukinov, D., Pugacheva, E., Qi, C.F., Wolffe, A., Ohlsson, R. and Lobanenkov, V.V. (2000) Functional association of CTCF with the insulator upstream of the H19 gene is parent of origin-specific and methylation-sensitive. Curr. Biol., 10, 853-856.
    • (2000) Curr. Biol. , vol.10 , pp. 853-856
    • Kanduri, C.1    Pant, V.2    Loukinov, D.3    Pugacheva, E.4    Qi, C.F.5    Wolffe, A.6    Ohlsson, R.7    Lobanenkov, V.V.8
  • 14
    • 0027496294 scopus 로고
    • Imprinting of human H19: Allele-specific CpG methylation, loss of the active allele in Wilms tumor, and potential for somatic allele switching
    • Zhang, Y., Shields, T., Crenshaw, T., Hao, Y., Moulton, T. and Tycko, B. (1993) Imprinting of human H19: allele-specific CpG methylation, loss of the active allele in Wilms tumor, and potential for somatic allele switching. Am. J. Hum. Genet., 53, 113-124.
    • (1993) Am. J. Hum. Genet. , vol.53 , pp. 113-124
    • Zhang, Y.1    Shields, T.2    Crenshaw, T.3    Hao, Y.4    Moulton, T.5    Tycko, B.6
  • 16
    • 0035510088 scopus 로고    scopus 로고
    • Large scale mapping of methylcytosines in CTCF-binding sites in the human H19 promoter and aberrant hypomethylation in human bladder cancer
    • Takai, D., Gonzales, F.A., Tsai, Y.C., Thayer, M.J. and Jones, P.A. (2001) Large scale mapping of methylcytosines in CTCF-binding sites in the human H19 promoter and aberrant hypomethylation in human bladder cancer. Hum. Mol. Genet., 10, 2619-2626.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 2619-2626
    • Takai, D.1    Gonzales, F.A.2    Tsai, Y.C.3    Thayer, M.J.4    Jones, P.A.5
  • 17
    • 0035393429 scopus 로고    scopus 로고
    • Loss of imprinting of insulin-like growth factor-II in Wilms' tumor commonly involves altered methylation but not mutations of CTCF or its binding site
    • Cui, H., Niemitz, E.L., Ravenel, J.D., Onyango, P., Brandenburg, S.A., Lobanenkov, V.V. and Feinberg, A.P. (2001) Loss of imprinting of insulin-like growth factor-II in Wilms' tumor commonly involves altered methylation but not mutations of CTCF or its binding site. Cancer Res., 61, 4947-4950.
    • (2001) Cancer Res. , vol.61 , pp. 4947-4950
    • Cui, H.1    Niemitz, E.L.2    Ravenel, J.D.3    Onyango, P.4    Brandenburg, S.A.5    Lobanenkov, V.V.6    Feinberg, A.P.7
  • 18
    • 0035895208 scopus 로고    scopus 로고
    • Loss of imprinting of the insulin-like growth factor II gene occurs by biallelic methylation in a core region of H19-associated CTCF-binding sites in colorectal cancer
    • Nakagawa, H., Chadwick, R.B., Peltomaki, P., Plass, C., Nakamura, Y. and de La Chapelle, A. (2001) Loss of imprinting of the insulin-like growth factor II gene occurs by biallelic methylation in a core region of H19-associated CTCF-binding sites in colorectal cancer. Proc. Natl Acad. Sci. USA, 98, 591-596.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 591-596
    • Nakagawa, H.1    Chadwick, R.B.2    Peltomaki, P.3    Plass, C.4    Nakamura, Y.5    de La Chapelle, A.6
  • 19
    • 0036392059 scopus 로고    scopus 로고
    • DNA methylation and genomic imprinting: Insights from cancer into epigenetic mechanisms
    • Feinberg, A.P., Cui, H. and Ohlsson, R. (2002) DNA methylation and genomic imprinting: insights from cancer into epigenetic mechanisms. Semin. Cancer Biol., 12, 389-398.
    • (2002) Semin. Cancer Biol. , vol.12 , pp. 389-398
    • Feinberg, A.P.1    Cui, H.2    Ohlsson, R.3
  • 20
    • 0037076432 scopus 로고    scopus 로고
    • BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma
    • Loukinov, D.I., Pugacheva, E., Vatolin, S., Pack, S.D., Moon, H., Chernukhin, I., Mannan, P., Larsson, E., Kanduri, C., Vostrov, A.A. et al. (2002) BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma. Proc. Natl Acad. Sci. USA, 99, 6806-6811.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 6806-6811
    • Loukinov, D.I.1    Pugacheva, E.2    Vatolin, S.3    Pack, S.D.4    Moon, H.5    Chernukhin, I.6    Mannan, P.7    Larsson, E.8    Kanduri, C.9    Vostrov, A.A.10
  • 21
    • 0036781505 scopus 로고    scopus 로고
    • The novel BORIS + CTCF gene family is uniquely involved in the epigenetics of normal biology and cancer
    • Klenova, E., Morse, H., Ohlsson, R. and Lobanenkov, V. (2002) The novel BORIS + CTCF gene family is uniquely involved in the epigenetics of normal biology and cancer. Semin. Cancer Biol., 12, 399-414.
    • (2002) Semin. Cancer Biol. , vol.12 , pp. 399-414
    • Klenova, E.1    Morse, H.2    Ohlsson, R.3    Lobanenkov, V.4
  • 23
    • 0027945263 scopus 로고
    • Promoter-specific imprinting of the human insulin-like growth factor-II gene
    • Vu, T.H. and Hoffman, A.R. (1994) Promoter-specific imprinting of the human insulin-like growth factor-II gene. Nature, 371, 714-717.
    • (1994) Nature , vol.371 , pp. 714-717
    • Vu, T.H.1    Hoffman, A.R.2
  • 24
    • 0028899741 scopus 로고
    • Promoter-specific IGF2 imprinting status and its plasticity during human liver development
    • Ekstrom, T.J., Cui, H., Li, X. and Ohlsson, R. (1995) Promoter-specific IGF2 imprinting status and its plasticity during human liver development. Development, 121, 309-316.
    • (1995) Development , vol.121 , pp. 309-316
    • Ekstrom, T.J.1    Cui, H.2    Li, X.3    Ohlsson, R.4
  • 25
    • 0029956737 scopus 로고    scopus 로고
    • Increased expression of the insulin-like growth factor-II gene in Wilms' tumor is not dependent on loss of genomic imprinting or loss of heterozygosity
    • Wang, W.H., Duan, J.X., Vu, T.H. and Hoffman, A.R. (1996) Increased expression of the insulin-like growth factor-II gene in Wilms' tumor is not dependent on loss of genomic imprinting or loss of heterozygosity. J. Biol. Chem., 271, 27863-27870.
    • (1996) J. Biol. Chem. , vol.271 , pp. 27863-27870
    • Wang, W.H.1    Duan, J.X.2    Vu, T.H.3    Hoffman, A.R.4
  • 26
    • 0037108564 scopus 로고    scopus 로고
    • Inhibition of proliferation in human MNNG/HOS osteosarcoma and SK-ES-1 Ewing sarcoma cell lines in vitro and in vivo by antagonists of growth hormone-releasing hormone: Effects on insulin-like growth factor II
    • Braczkowski, R., Schally, A.V., Plonowski, A., Varga, J.L., Groot, K., Krupa, M. and Armatis, P. (2002) Inhibition of proliferation in human MNNG/HOS osteosarcoma. and SK-ES-1 Ewing sarcoma cell lines in vitro and in vivo by antagonists of growth hormone-releasing hormone: effects on insulin-like growth factor II. Cancer, 95, 1735-1745.
    • (2002) Cancer , vol.95 , pp. 1735-1745
    • Braczkowski, R.1    Schally, A.V.2    Plonowski, A.3    Varga, J.L.4    Groot, K.5    Krupa, M.6    Armatis, P.7
  • 27
    • 0032419812 scopus 로고    scopus 로고
    • Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2
    • Thorvaldsen, J.L., Duran, K.L. and Bartolomei, M.S. (1998) Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2. Genes Dev., 12, 3693-3702.
    • (1998) Genes Dev. , vol.12 , pp. 3693-3702
    • Thorvaldsen, J.L.1    Duran, K.L.2    Bartolomei, M.S.3
  • 28
    • 0028089079 scopus 로고
    • Overlapping patterns of IGF2 and H19 expression during human development: Biallelic IGF2 expression correlates with a lack of H19 expression
    • Ohlsson, R., Hedborg, F., Holmgren, L., Walsh, C. and Ekstrom, T.J. (1994) Overlapping patterns of IGF2 and H19 expression during human development: biallelic IGF2 expression correlates with a lack of H19 expression. Development, 120, 361-368.
    • (1994) Development , vol.120 , pp. 361-368
    • Ohlsson, R.1    Hedborg, F.2    Holmgren, L.3    Walsh, C.4    Ekstrom, T.J.5
  • 29
    • 0028356544 scopus 로고
    • Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumour
    • Steenman, M.J., Rainier, S., Dobry, C.J., Grundy, P., Horon, I.L. and Feinberg, A.P. (1994) Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumour. Nat. Genet., 7, 433-439.
    • (1994) Nat. Genet. , vol.7 , pp. 433-439
    • Steenman, M.J.1    Rainier, S.2    Dobry, C.J.3    Grundy, P.4    Horon, I.L.5    Feinberg, A.P.6
  • 31
    • 0028935017 scopus 로고
    • Epigenetic changes encompassing the IGF2/H19 locus associated with relaxation of IGF2 imprinting and silencing of H19 in Wilms tumor
    • Taniguchi, T., Sullivan, M.J., Ogawa, O. and Reeve, A.E. (1995) Epigenetic changes encompassing the IGF2/H19 locus associated with relaxation of IGF2 imprinting and silencing of H19 in Wilms tumor. Proc. Natl Acad. Sci. USA., 92, 2159-2163.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 2159-2163
    • Taniguchi, T.1    Sullivan, M.J.2    Ogawa, O.3    Reeve, A.E.4
  • 32
    • 0030053512 scopus 로고    scopus 로고
    • High incidence of loss of heterozygosity and abnormal imprinting of H19 and IGF2 genes in invasive cervical carcinomas. Uncoupling of H19 and IGF2 expression and biallelic hypomethylation of H19
    • Douc-Rasy, S., Barrois, M., Fogel, S., Ahomadegbe, J.C., Stehelin, D., Coll, J. and Rion, G. (1996) High incidence of loss of heterozygosity and abnormal imprinting of H19 and IGF2 genes in invasive cervical carcinomas. Uncoupling of H19 and IGF2 expression and biallelic hypomethylation of H19. Oncogene, 12, 423-430.
    • (1996) Oncogene , vol.12 , pp. 423-430
    • Douc-Rasy, S.1    Barrois, M.2    Fogel, S.3    Ahomadegbe, J.C.4    Stehelin, D.5    Coll, J.6    Rion, G.7
  • 33
    • 0031770813 scopus 로고    scopus 로고
    • Frequent loss of imprinting of the H19 and IGF-II genes in ovarian tumors
    • Kim, H.T., Choi, B.H., Niikawa, N., Lee, T.S. and Chang, S.I. (1998) Frequent loss of imprinting of the H19 and IGF-II genes in ovarian tumors. Am. J. Med. Genet., 80, 391-395.
    • (1998) Am. J. Med. Genet. , vol.80 , pp. 391-395
    • Kim, H.T.1    Choi, B.H.2    Niikawa, N.3    Lee, T.S.4    Chang, S.I.5
  • 34
    • 0033604466 scopus 로고    scopus 로고
    • Frequent loss of imprinting at the IGF2 and H19 genes in head and neck squamous carcinoma
    • el-Naggar, A.K., Lai, S., Tucker, S.A., Clayman, G.L., Goepfert, H., Hong, W.K. and Huff, V. (1999) Frequent loss of imprinting at the IGF2 and H19 genes in head and neck squamous carcinoma. Oncogene, 18, 7063-7069.
    • (1999) Oncogene , vol.18 , pp. 7063-7069
    • el-Naggar, A.K.1    Lai, S.2    Tucker, S.A.3    Clayman, G.L.4    Goepfert, H.5    Hong, W.K.6    Huff, V.7
  • 36
    • 0342572600 scopus 로고    scopus 로고
    • Deletion of a silencer element in Igf2 results in loss of imprinting independent of H19
    • Constancia, M., Dean, W., Lopes, S., Moore, T., Kelsey, G. and Reik, W. (2000) Deletion of a silencer element in Igf2 results in loss of imprinting independent of H19. Nat. Genet., 26, 203-206.
    • (2000) Nat. Genet. , vol.26 , pp. 203-206
    • Constancia, M.1    Dean, W.2    Lopes, S.3    Moore, T.4    Kelsey, G.5    Reik, W.6
  • 38
    • 0035311042 scopus 로고    scopus 로고
    • Deletion of a nuclease-sensitive region between the Igf2 and H19 genes leads to Igf2 misregulation and increased adiposity
    • Jones, B.K., Levorse, J. and Tilghman, S.M. (2001) Deletion of a nuclease-sensitive region between the Igf2 and H19 genes leads to Igf2 misregulation and increased adiposity. Hum. Mol. Genet., 10, 807-814.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 807-814
    • Jones, B.K.1    Levorse, J.2    Tilghman, S.M.3
  • 39
    • 0029931018 scopus 로고    scopus 로고
    • Alterations in the promoter-specific imprinting of the insulin-like growth factor-II gene in Wilms' tumor
    • Vu, T.H. and Hoffman, A. (1996) Alterations in the promoter-specific imprinting of the insulin-like growth factor-II gene in Wilms' tumor. J. Biol. Chem., 271, 9014-9023.
    • (1996) J. Biol. Chem. , vol.271 , pp. 9014-9023
    • Vu, T.H.1    Hoffman, A.2
  • 40
    • 0034426034 scopus 로고    scopus 로고
    • Hot-stop PCR: A simple and general assay for linear quantitation of allele ratios
    • Uejima, H., Lee, M.P., Cui, H. and Feinberg, A.P. (2000) Hot-stop PCR: a simple and general assay for linear quantitation of allele ratios. Nat. Genet., 25, 375-376.
    • (2000) Nat. Genet. , vol.25 , pp. 375-376
    • Uejima, H.1    Lee, M.P.2    Cui, H.3    Feinberg, A.P.4
  • 43
    • 0030825309 scopus 로고    scopus 로고
    • COBRA: A sensitive and quantitative DNA methylation assay
    • Xiong, Z. and Laird, P.W. (1997) COBRA: a sensitive and quantitative DNA methylation assay. Nucl. Acids Res., 25, 2532-2534.
    • (1997) Nucl. Acids Res. , vol.25 , pp. 2532-2534
    • Xiong, Z.1    Laird, P.W.2


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