Gliclazide produces high-affinity block of KATP, channels in mouse isolated pancreatic beta cells but not rat heart or arterial smooth muscle cells

Diabetologia

Volumn 44, Issue 8, 2001, Pages 1019-1025

  Lawrence, C L ^a   Proks, P ^a   Rodrigo, G C ^a   Jones, P ^a   Hayabuchi, Y ^a   Standen, N B ^a   Ashcroft, F M ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

ATP sensitive K+ channel; Gliclazide; Heart; Smooth muscle; Sulphonylurea receptor

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLIBENCLAMIDE; GLICLAZIDE; MAGNESIUM; POTASSIUM CHANNEL; SULFONYLUREA; SULFONYLUREA RECEPTOR;

ANIMAL CELL; ARTERY MUSCLE; ARTICLE; CELL ISOLATION; CELL MEMBRANE; CELL METABOLISM; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; DRUG SPECIFICITY; ELECTRIC ACTIVITY; HEART MUSCLE CELL; IC 50; INSULIN RELEASE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY;

ANIMALS; ELECTRIC CONDUCTIVITY; GLICLAZIDE; HEART; ISLETS OF LANGERHANS; MALE; MICE; MUSCLE, SMOOTH, VASCULAR; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RATS; RATS, WISTAR;

EID: 0034883322     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250100595     Document Type: Article

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