Increased [3H]phorbol ester binding in rat cerebellar granule cells and inhibition of 45Ca2+ buffering in rat cerebellum by hydroxylated polychlorinated biphenyls

NeuroToxicology

Volumn 24, Issue 2, 2003, Pages 187-198

  Kodavanti, Prasada Rao S ^a   Ward, Thomas R ^a   Derr Yellin, Ethel C ^a,b   McKinney, James D ^a   Tilson, Hugh A ^a  

^a Mail Drop E 243 03   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

45Ca2+ sequestration; Cerebellar granule cells; Cerebellum; Hydroxylated polychlorinated biphenyls; Neurotoxicity; Structure activity relationships; 3H Phorbol ester binding

Indexed keywords

2',4',6' TRICHLORO 4 BIPHENYLOL; 2',5' DICHLORO 4 BIPHENYLOL; 2,2',4',5,5' PENTACHLORO 4 BIPHENYLOL; 2,2',5' TRICHLORO 4 BIPHENYLOL; 3,4',5 TRICHLORO 4 BIPHENYLOL; 3,5 DICHLORO 4 BIPHENYLOL; CALCIUM ION; CHLORINE; PHORBOL ESTER; POLYCHLORINATED BIPHENYL; PROTEIN KINASE C; UNCLASSIFIED DRUG; CALCIUM; DIAGNOSTIC AGENT; PHORBOL DIBUTYRATE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN MICROSOME; CALCIUM HOMEOSTASIS; CEREBELLUM; CHEMICAL BINDING; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME LOCALIZATION; FEMALE; GRANULE CELL; HYDROXYLATION; IN VITRO STUDY; IONIZATION; MALE; MAMMAL; METABOLITE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; ANIMAL; CELL GRANULE; CYTOLOGY; DRUG EFFECT; LONG EVANS RAT; METABOLISM; MICROSOME; PHYSIOLOGY; POLLUTANT; PREGNANCY;

ANIMALIA; MAMMALIA;

ANIMALS; CALCIUM; CALCIUM RADIOISOTOPES; CEREBELLUM; CYTOPLASMIC GRANULES; ENVIRONMENTAL POLLUTANTS; FEMALE; HYDROXYLATION; MALE; MICROSOMES; PHORBOL 12,13-DIBUTYRATE; POLYCHLORINATED BIPHENYLS; PREGNANCY; RATS; RATS, LONG-EVANS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037334978     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-813X(02)00215-2     Document Type: Article

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