Molecular cloning and analysis of the rat inducible nitric oxide synthase gene promoter in aortic smooth muscle cells

Biochemical Pharmacology

Volumn 55, Issue 11, 1998, Pages 1873-1880

  Zhang, Hanfang ^a   Chen, Xunsheng ^a   Teng, Xingwu ^a   Snead, Connie ^a   Catravas, John D ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Cytokines; INOS promoter; LPS; NF B; Vascular smooth muscle cells

Indexed keywords

CYTOKINE; DNA FRAGMENT; INTERLEUKIN 1; LUCIFERASE; NITRIC OXIDE SYNTHASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; AORTA MEDIA; ARTICLE; CELL CULTURE; DNA SEQUENCE; DNA TRANSFECTION; ENZYME ASSAY; GENE CONTROL; GENE EXPRESSION; GENETIC ANALYSIS; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; RAT; VASCULAR SMOOTH MUSCLE;

ANIMALS; AORTA; BASE SEQUENCE; CELLS, CULTURED; CLONING, MOLECULAR; CYTOKINES; DNA; ENZYME INDUCTION; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; LIPOPOLYSACCHARIDES; MOLECULAR SEQUENCE DATA; MUSCLE, SMOOTH, VASCULAR; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PROMOTER REGIONS (GENETICS); RATS; RATS, WISTAR;

EID: 0032100679     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(98)00078-1     Document Type: Article

References (31)

1. Harald H.H., Schmidt W., Walter U. NO at work. Cell. 78:1994;919-925.
2. Moncada S., Palmer R.M., Higgs E.A. Nitric oxide Physiology, pathophysiology, and pharmacology. Pharmacol Rev. 43:1991;109-142.
3. Nathan C., Xie Q-W. Nitric oxide synthase Roles, tolls, and controls. Cell. 78:1994;915-918.
4. G-methyl-L-arginine, an inhibitor of nitric oxide synthesis. Biochem Biophys Res Commun. 172:1990;1132-1138.
5. Wright C.E., Rees D.D., Moncada S. Protective and pathological roles of nitric oxide in endotoxin shock. Cardiovasc Res. 26:1992;48-57.
6. Moritz T., Niederle N., Baumann J., May D., Kurschel E., Osieka R., Kempeni J., Schlick E., Schmidt C.G. Phase I study of recombinant human tumor necrosis factor α in advanced malignant disease. Cancer Immunol Immunother. 29:1989;144-150.
7. Hibbs J.B. Jr, Wesrenfelder C., Taintor R., Vavrin Z., Kablitz C., Baranowski R.L., Ward J.H., Menlove R.L., McMurry M.P., Kushner J.P., Samlowski W.E.J. Evidence for cytokine inducible nitric oxide synthesis from L-arginine in patients receiving interleukin-2 therapy. J Clin Invest. 89:1992;867-877.
8. Xie Q-W, Whisnant R., Nathan C. Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon γ and bacterial lipopolysaccharide. J Exp Med. 177:1993;1779-1784.
9. Xie Q-W, Nathan C. The high-output nitric oxide pathway Role and regulation. J Leukoc Biol. 56:1994;576-582.
10. Lowenstein C.J., Alley E.W., Raval P., Snowman A.M., Snyder S.H., Russell S.W., Murphy W.J. Macrophage nitric oxide synthase gene Two upstream regions mediate induction by interferon γ and lipopolysaccharide. Proc Natl Acad Sci USA. 90:1993;9730-9734.
11. Xie Q-W, Kashiwabara Y., Nathan C. Role of transcription factor NF-κB/Rel in induction of nitric oxide synthase. J Biol Chem. 269:1994;4705-4708.
12. Martin E., Nathan C., Xie Q-W. Role of interferon regulation factor 1 in induction of nitric oxide synthase. J Exp Med. 180:1994;977-984.
13. Kleinert H., Euchenhofer C., Ihrig-Biedert I., Förstermann U. Glucocorticoids inhibit the induction of nitric oxide synthase II by down-regulating cytokine-induced activity of transcription factor nuclear factor-κB. Mol Pharmacol. 49:1996;15-21.
14. De Vera M.E., Shapiro R.A., Nussler A.K., Mudgett J.S., Simmons R.L., Morris S.M. Jr, Billiar T.R., Geller D.A. Transcriptional regulation of human inducible nitric oxide synthase (NOS2) gene by cytokines Initial analysis of the human NOS2 promoter. Proc Natl Acad Sci USA. 93:1996;1054-1059.
15. Spitsin S.V., Koprowski H., Michaels F.H. Characterization and functional analysis of the human inducible nitric oxide synthase gene promoter. Mol Med. 2:1996;226-235.
16. Eberhardt W., Kunz D., Hummel R., Pfeilschifer J. Molecular cloning of rat inducible nitric oxide synthase gene promoter. Biochem Biophys Res Commun. 223:1996;752-756.
17. MacMicking J.D., Nathan C., Nom G., Chartrain N., Fletcher D.S., Trumbauer M., Stevens K., Xie Q-W, Sokol K., Hutchinson N., Chen H., Mudgett J.S. Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase. Cell. 81:1995;641-650.
18. Spink J., Cohen J., Evans T.J. The cytokine responsive vascular smooth muscle cell enhancer of inducible nitric oxide synthase. J Biol Chem. 270:1995;29541-29547.
19. Perrella K.A., Patterson C., Tan L., Yet S-F, Hsieh C-M, Yoshizumi M., Lee M-E. Suppression of interleukin-1β-induced nitric-oxide synthase promoter/enhancer activity by transforming growth factor-β1 in vascular smooth muscle cells. Evidence for mechanisms other than NF-κB. J Biol Chem. 271:1996;13776-13780.
20. Geinsterfer A.A.T., Peach M.J., Owens G.O. Angiotensin II induces hypertrophy but not hyperplasia of cultured rat aortic smooth muscle cells. Circ Res. 62:1988;749-756.
21. Siebert P.D., Chenchik A., Kellogg D.E., Lukyanov K.A., Lukyanov S.A. An improved PCR method for walking in uncloned genomic DNA. Nucleic Acids Res. 23:1995;1087-1088.
22. Geng Y.J., Almqvist M., Hansson G.K. cDNA cloning and expression of inducible nitric oxide synthase from rat vascular smooth muscle cells. Biochim Biophys Acta. 1218:1994;421-424.
23. Sambrook J, Fritsch EF and Maniatis T, Molecular Cloning: A Laboratory Manual I.38-I.41., Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1989.
24. Zhang H., Henderson H., Gagne S.E., Clee S.M., Miao L., Liu G., Hayden M.R. Common sequence variants of lipoprotein lipase Standardized studies of in vitro expression and catalytic function. Biochim Biophys Acta. 1302:1996;159-166.
25. 15N]nitrate in biological fluids. Anal Biochem. 126:1982;131-138.
26. Marczin N., Go C.Y., Papapetropoulos A., Hattori R., Catravas J.D. Induction of nitric oxide synthase by protein synthesis inhibition in aortic smooth muscle cells. Br J Pharmacol. 123:1998;1000-1008.
27. Luss H., DiSilvio M., Litton A.L., Vedia L.M., Nussler A.K., Billiar T.R. Inhibition of nitric oxide synthesis enhances the expression of inducible nitric oxide synthase mRNA and protein in a model of chronic liver inflammation. Biochem Biophys Res Commun. 204:1994;635-640.
28. Park S.K., Lin H.L., Murphy S. Nitric oxide limits transcriptional induction of oxide synthase in CNS glial cells. Biochem Biophys Res Commun. 201:1994;762-768.
29. G-monomethyl-L-arginine. Biochem J. 316:1996;209-215.
30. Saunders L.A., Spink J.M. Differential response of VSMC preparations to LPS is mediated via members of the Rel family of transcriptional activators. Endothelium. 3:1995;S50.
31. Lin A.W., Chang C.C., McCormick C.C. Molecular cloning and expression of an avian macrophage nitric-oxide synthase cDNA and the analysis of the genomic 5′-flanking region. J Biol Chem. 271:1996;11911-11919.