메뉴 건너뛰기




Volumn 369, Issue 3, 2003, Pages 583-591

Hepatocyte nuclear factor-6 stimulates transcription of the α-fetoprotein gene and synergizes with the retinoic-acid-receptor-related orphan receptor α-4

Author keywords

Liver differentiation; Transcription factor

Indexed keywords

DNA; GENES; ORGANIC ACIDS; PROTEINS;

EID: 0037330235     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20021229     Document Type: Article
Times cited : (9)

References (47)
  • 2
    • 0034609736 scopus 로고    scopus 로고
    • Cooperativity: Action at a distance in a classic system
    • Koudelka, G. B. (2000) Cooperativity: action at a distance in a classic system. Curr. Biol. 10, R704-R707
    • (2000) Curr. Biol. , vol.10
    • Koudelka, G.B.1
  • 3
    • 0035799284 scopus 로고    scopus 로고
    • Cooperativity in transcriptional control
    • Courey, A. J. (2001) Cooperativity In transcriptional control. Curr. Biol. 11, R250-R252
    • (2001) Curr. Biol. , vol.11
    • Courey, A.J.1
  • 4
    • 0033028762 scopus 로고    scopus 로고
    • Chromatin and transcription in Saccharomyces cerevisiae
    • Perez-Martin, J. (1999) Chromatin and transcription in Saccharomyces cerevisiae. FEMS Microbiol. Rev. 23, 503-523
    • (1999) FEMS Microbiol. Rev. , vol.23 , pp. 503-523
    • Perez-Martin, J.1
  • 5
    • 0034840431 scopus 로고    scopus 로고
    • Chromatin goes global
    • Berger, S. L. and Felsenfeld, G. (2001) Chromatin goes global. Mol. Cell 8, 263-268
    • (2001) Mol. Cell , vol.8 , pp. 263-268
    • Berger, S.L.1    Felsenfeld, G.2
  • 7
    • 0029023951 scopus 로고
    • Cooperation between transcription factors regulates liver development
    • Aran, A., Cassuto, H. and Reshef, L. (1995) Cooperation between transcription factors regulates liver development. Biol. Neonate 67, 387-396
    • (1995) Biol. Neonate , vol.67 , pp. 387-396
    • Aran, A.1    Cassuto, H.2    Reshef, L.3
  • 8
    • 0029962261 scopus 로고    scopus 로고
    • Liver-enriched transcription factors and hepatocyte differentiation
    • Cereghini, S. (1996) Liver-enriched transcription factors and hepatocyte differentiation. FASEB J. 10, 267-282
    • (1996) FASEB J. , vol.10 , pp. 267-282
    • Cereghini, S.1
  • 9
    • 0032949466 scopus 로고    scopus 로고
    • Liver enriched transcription factors and differentiation of hepatocellular carcinoma
    • Hayashi, Y., Wang, W., Ninomiya, T., Nagano, H., Ohta, K. and Itoh, H. (1999) Liver enriched transcription factors and differentiation of hepatocellular carcinoma. Mol. Pathol. 52, 19-24
    • (1999) Mol. Pathol. , vol.52 , pp. 19-24
    • Hayashi, Y.1    Wang, W.2    Ninomiya, T.3    Nagano, H.4    Ohta, K.5    Itoh, H.6
  • 10
    • 0036200587 scopus 로고    scopus 로고
    • Liver-enriched transcription factors in liver function and development. Part I: The hepatocyte nuclear factor network and liver-specific gene expression
    • Schrem, H., Klempnauer, J. and Borlak, J. (2002) Liver-enriched transcription factors in liver function and development. Part I: the hepatocyte nuclear factor network and liver-specific gene expression. Pharmacol. Rev. 54, 129-158
    • (2002) Pharmacol. Rev. , vol.54 , pp. 129-158
    • Schrem, H.1    Klempnauer, J.2    Borlak, J.3
  • 11
    • 0342614209 scopus 로고    scopus 로고
    • Unified nomenclature for the winged helix/forkhead transcription factors
    • Kaestner, K. H., Knochel, W. and Martinez, D. E. (2000) Unified nomenclature for the winged helix/forkhead transcription factors. Genes Dev. 14, 142-146
    • (2000) Genes Dev. , vol.14 , pp. 142-146
    • Kaestner, K.H.1    Knochel, W.2    Martinez, D.E.3
  • 12
    • 0034456218 scopus 로고    scopus 로고
    • Involvment of STAT5 (Signal Transducer and Activator of Transcription 5) and HNF-4 (Hepatocyte Nuclear Factor-4) in the transcriptional control of the hnf-6 gene by growth hormone
    • Lahuna, O., Rastegar, M., Maiter, D., Thissen, J.-P., Lemaigre, F. P. and Rousseau, G. G. (2000) Involvment of STAT5 (Signal Transducer and Activator of Transcription 5) and HNF-4 (Hepatocyte Nuclear Factor-4) in the transcriptional control of the hnf-6 gene by growth hormone. Mol. Endocrinol. 14, 285-294
    • (2000) Mol. Endocrinol. , vol.14 , pp. 285-294
    • Lahuna, O.1    Rastegar, M.2    Maiter, D.3    Thissen, J.-P.4    Lemaigre, F.P.5    Rousseau, G.G.6
  • 13
    • 0031573874 scopus 로고    scopus 로고
    • HNF-6 is expressed in endoderm derivatives and nervous system of the mouse embryo and participates to the cross-regulatory network of liver-enriched transcription factors
    • Landry, C., Clotman, F., Hioki, T., Oda, H., Picard, J. J., Lemaigre, F. P. and Rousseau, G. G. (1997) HNF-6 is expressed in endoderm derivatives and nervous system of the mouse embryo and participates to the cross-regulatory network of liver-enriched transcription factors. Dev. Biol. 192, 247-257
    • (1997) Dev. Biol. , vol.192 , pp. 247-257
    • Landry, C.1    Clotman, F.2    Hioki, T.3    Oda, H.4    Picard, J.J.5    Lemaigre, F.P.6    Rousseau, G.G.7
  • 14
    • 0031573810 scopus 로고    scopus 로고
    • The cut-homeodomain transcriptional activator HNF-6 is coexpressed with its target gene HNF-3β in the developing murine liver and pancreas
    • Rausa, F., Samadani, U., Ye, H., Lim, L., Fletcher, C. F., Jenkins, N. A., Copeland, N. G. and Costa, R. H. (1997) The cut-homeodomain transcriptional activator HNF-6 is coexpressed with its target gene HNF-3β in the developing murine liver and pancreas. Dev. Biol. 192, 228-246
    • (1997) Dev. Biol. , vol.192 , pp. 228-246
    • Rausa, F.1    Samadani, U.2    Ye, H.3    Lim, L.4    Fletcher, C.F.5    Jenkins, N.A.6    Copeland, N.G.7    Costa, R.H.8
  • 17
    • 0033022699 scopus 로고    scopus 로고
    • α-fetoprotein gene regulation: Lessons from transgenic mice
    • Spear, B. T. (1999) α-fetoprotein gene regulation: lessons from transgenic mice. Semin. Cancer Biol. 9, 109-116
    • (1999) Semin. Cancer Biol. , vol.9 , pp. 109-116
    • Spear, B.T.1
  • 18
    • 0033630189 scopus 로고    scopus 로고
    • Molecular mechanisms of α-fetoprotein gene expression
    • Lazarevich, N. L. (2000) Molecular mechanisms of α-fetoprotein gene expression. Biochemistry (Moscow) 65, 117-133
    • (2000) Biochemistry (Moscow) , vol.65 , pp. 117-133
    • Lazarevich, N.L.1
  • 19
    • 0034475163 scopus 로고    scopus 로고
    • Human α-fetoprotein transcriptional regulatory sequences. Application to gene therapy
    • Tamaoki, T. (2000) Human α-fetoprotein transcriptional regulatory sequences. Application to gene therapy. Adv. Exp. Med. Biol. 465, 47-56
    • (2000) Adv. Exp. Med. Biol. , vol.465 , pp. 47-56
    • Tamaoki, T.1
  • 20
    • 0030443565 scopus 로고    scopus 로고
    • Chicken ovalbumin upstream promoter-transcription factor, hepatocyte nuclear factor 3, and CCAAT/enhancer binding protein control the far-upstream enhancer of the rat α-fetoprotein gene
    • Thomassin, H., Bois-Joyeux, B., Delille, R., Ikonomova, R. and Danan, J. L. (1996) Chicken ovalbumin upstream promoter-transcription factor, hepatocyte nuclear factor 3, and CCAAT/enhancer binding protein control the far-upstream enhancer of the rat α-fetoprotein gene. DNA Cell. Biol. 15, 1063-1074
    • (1996) DNA Cell. Biol. , vol.15 , pp. 1063-1074
    • Thomassin, H.1    Bois-Joyeux, B.2    Delille, R.3    Ikonomova, R.4    Danan, J.L.5
  • 21
    • 0028168047 scopus 로고
    • Characterization of the distal αfetoprotein enhancer, a strong, long distance, liver-specific activator
    • Groupp, E. R., Crawford, N. and Locker, J. (1994) Characterization of the distal αfetoprotein enhancer, a strong, long distance, liver-specific activator. J. Biol. Chem. 269, 22178-22187
    • (1994) J. Biol. Chem. , vol.269 , pp. 22178-22187
    • Groupp, E.R.1    Crawford, N.2    Locker, J.3
  • 22
    • 0028981384 scopus 로고
    • Individual mouse α-fetoprotein enhancer elements exhibit different patterns of tissue-specific and hepatic position-dependent activities
    • Ramesh, T. M., Ellis, A. W. and Spear, B. T. (1995) Individual mouse α-fetoprotein enhancer elements exhibit different patterns of tissue-specific and hepatic position-dependent activities. Mol. Cell. Biol. 15, 4947-4955
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 4947-4955
    • Ramesh, T.M.1    Ellis, A.W.2    Spear, B.T.3
  • 23
    • 0029009894 scopus 로고
    • Molecular analysis of the distal enhancer of the mouse α-fetoprotein gene
    • Millonig, J. H., Emerson, J. A., Levorse, J. M. and Tilghman, S. M. (1995) Molecular analysis of the distal enhancer of the mouse α-fetoprotein gene. Mol. Cell. Biol. 15, 3848-3856
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3848-3856
    • Millonig, J.H.1    Emerson, J.A.2    Levorse, J.M.3    Tilghman, S.M.4
  • 24
    • 0033574663 scopus 로고    scopus 로고
    • A unified nomenclature system for the nuclear receptor superfamily
    • Committee, N. R. N. (1999) A unified nomenclature system for the nuclear receptor superfamily. Cell 97, 161-163
    • (1999) Cell , vol.97 , pp. 161-163
    • Committee, N.R.N.1
  • 25
    • 0033793493 scopus 로고    scopus 로고
    • Modulation of the far-upstream enhancer of the rat α-fetoprotein gene by members of the RORα, Rev-erbα, and Rev-erbβ groups of monomeric orphan nuclear receptors
    • Bois-Joyeux, B., Chauvet, C., Nacer-Cherif, H., Bergeret, W., Mazure, N., Giguere, V., Laudet, V. and Danan, J. L. (2000) Modulation of the far-upstream enhancer of the rat α-fetoprotein gene by members of the RORα, Rev-erbα, and Rev-erbβ groups of monomeric orphan nuclear receptors. DNA Cell Biol. 19, 589-599
    • (2000) DNA Cell Biol. , vol.19 , pp. 589-599
    • Bois-Joyeux, B.1    Chauvet, C.2    Nacer-Cherif, H.3    Bergeret, W.4    Mazure, N.5    Giguere, V.6    Laudet, V.7    Danan, J.L.8
  • 26
    • 0037081868 scopus 로고    scopus 로고
    • Age-related phenotypes in the staggerer mouse expand the RORα nuclear receptor's role beyond the cerebellum
    • Jarvis, C. I., Staels, B., Brugg, B., Lemaigre-Dubreuil, Y., Tedgui, A. and Mariani, J. (2002) Age-related phenotypes in the staggerer mouse expand the RORα nuclear receptor's role beyond the cerebellum. Mol. Cell. Endocrinol. 186, 1-5
    • (2002) Mol. Cell. Endocrinol. , vol.186 , pp. 1-5
    • Jarvis, C.I.1    Staels, B.2    Brugg, B.3    Lemaigre-Dubreuil, Y.4    Tedgui, A.5    Mariani, J.6
  • 27
    • 0029824047 scopus 로고    scopus 로고
    • The transcriptional activator hepatocyte nuclear factor 6 regulates liver gene expression
    • Samadani, U. and Costa, R. H. (1996) The transcriptional activator hepatocyte nuclear factor 6 regulates liver gene expression. Mol. Cell. Biol. 16, 6273-6284
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 6273-6284
    • Samadani, U.1    Costa, R.H.2
  • 28
    • 0032577494 scopus 로고    scopus 로고
    • Isoforms of hepatocyte nuclear factor-6 differ in DNA-binding properties, contain a bifunctional homoeodomain, and define the new ONECUT class of homeodomain proteins
    • Lannoy, V. J., Burglin, T. R., Rousseau, G. G. and Lemaigre, F. P. (1998) Isoforms of hepatocyte nuclear factor-6 differ in DNA-binding properties, contain a bifunctional homoeodomain, and define the new ONECUT class of homeodomain proteins. J. Biol. Chem. 273, 13552-13562
    • (1998) J. Biol. Chem. , vol.273 , pp. 13552-13562
    • Lannoy, V.J.1    Burglin, T.R.2    Rousseau, G.G.3    Lemaigre, F.P.4
  • 29
    • 0027967521 scopus 로고
    • Hepatocyte nuclear factor-3 (HNF-3) binds to the insulin response sequence in the IGF binding protein-1 (IGFBP-1) promoter and enhances promoter function
    • Unterman, T. G., Fareeduddin, A., Harris, M. A., Goswami, R. G., Porcella, A., Costa, R. H. and Lacson, R. G. (1994) Hepatocyte nuclear factor-3 (HNF-3) binds to the insulin response sequence in the IGF binding protein-1 (IGFBP-1) promoter and enhances promoter function. Biochem. Biophys. Res. Commun. 203, 1835-1841
    • (1994) Biochem. Biophys. Res. Commun. , vol.203 , pp. 1835-1841
    • Unterman, T.G.1    Fareeduddin, A.2    Harris, M.A.3    Goswami, R.G.4    Porcella, A.5    Costa, R.H.6    Lacson, R.G.7
  • 30
    • 0028197552 scopus 로고
    • Isoform-specific amino-terminal domains dictate DNA-binding properties of RORα, a novel family of orphan hormone nuclear receptors
    • Giguere, V., Tini, M., Flock, G., Ong, E., Evans, R. M. and Otulakowski, G. (1994) Isoform-specific amino-terminal domains dictate DNA-binding properties of RORα, a novel family of orphan hormone nuclear receptors. Genes Dev. 8, 538-553
    • (1994) Genes Dev. , vol.8 , pp. 538-553
    • Giguere, V.1    Tini, M.2    Flock, G.3    Ong, E.4    Evans, R.M.5    Otulakowski, G.6
  • 31
    • 0025177424 scopus 로고
    • Absence of substantial bending in Xenopus laevis transcription factor IIIA-DNA complexes
    • Zwieb, C. and Brown, R. (1990) Absence of substantial bending in Xenopus laevis transcription factor IIIA-DNA complexes. Nucleic Acids Res. 11, 583-587
    • (1990) Nucleic Acids Res. , vol.11 , pp. 583-587
    • Zwieb, C.1    Brown, R.2
  • 33
    • 0029841390 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 6, a transcription factor that contains a novel type of homoeodomain and a single cut domain
    • Lemaigre, F. P., Durviaux, S. M., Truong, O., Lannoy, V. J., Hsuan, J. J. and Rousseau, G. G. (1996) Hepatocyte nuclear factor 6, a transcription factor that contains a novel type of homoeodomain and a single cut domain. Proc. Natl. Acad. Sci. U.S.A. 93, 9460-9464
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 9460-9464
    • Lemaigre, F.P.1    Durviaux, S.M.2    Truong, O.3    Lannoy, V.J.4    Hsuan, J.J.5    Rousseau, G.G.6
  • 34
    • 0029004768 scopus 로고
    • Hepatocyte nuclear factor 3 determines the amplitude of the glucocorticoid response of the rat tyrosine aminotransferase gene
    • Roux, J., Pictet, R. and Grange, T. (1995) Hepatocyte nuclear factor 3 determines the amplitude of the glucocorticoid response of the rat tyrosine aminotransferase gene. DNA Cell. Biol. 14, 385-396
    • (1995) DNA Cell. Biol. , vol.14 , pp. 385-396
    • Roux, J.1    Pictet, R.2    Grange, T.3
  • 35
    • 0025257024 scopus 로고
    • Sp 1 can displace GHF-1 on its distal binding site and stimulate transcription from the growth hormone gene promoter in vitro
    • Lemaigre, F. P., Lafontaine, D. A., Courtois, S., Durviaux, S. M. and Rousseau, G. G. (1990) Sp 1 can displace GHF-1 on its distal binding site and stimulate transcription from the growth hormone gene promoter in vitro. Mol. Cell. Biol. 10, 1811-1814
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 1811-1814
    • Lemaigre, F.P.1    Lafontaine, D.A.2    Courtois, S.3    Durviaux, S.M.4    Rousseau, G.G.5
  • 36
    • 0030798605 scopus 로고    scopus 로고
    • Clues and consequences of DNA bending in transcription
    • Perez-Martin, J. and de Lorenzo, V. (1997) Clues and consequences of DNA bending in transcription. Annu. Rev. Microbiol. 51, 593-628
    • (1997) Annu. Rev. Microbiol. , vol.51 , pp. 593-628
    • Perez-Martin, J.1    De Lorenzo, V.2
  • 37
    • 0032524123 scopus 로고    scopus 로고
    • Transcriptional cooperativity: Bending over backwards and doing the flip
    • Kerppola, T. K. (1998) Transcriptional cooperativity: bending over backwards and doing the flip. Structure 6, 549-554
    • (1998) Structure , vol.6 , pp. 549-554
    • Kerppola, T.K.1
  • 38
    • 0027270989 scopus 로고
    • Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5
    • Clark, K. L., Halay, E. D., Lai, E. and Burley, S. K. (1993) Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5. Nature (London) 364, 412-420
    • (1993) Nature (London) , vol.364 , pp. 412-420
    • Clark, K.L.1    Halay, E.D.2    Lai, E.3    Burley, S.K.4
  • 39
    • 0021268779 scopus 로고
    • The locus of sequence-directed and protein-induced DNA bending
    • Wu, H. M. and Crothers, D. M. (1984) The locus of sequence-directed and protein-induced DNA bending. Nature (London) 308, 509-513
    • (1984) Nature (London) , vol.308 , pp. 509-513
    • Wu, H.M.1    Crothers, D.M.2
  • 40
    • 0023771741 scopus 로고
    • Empirical estimation of protein-induced DNA bending angles: Applications to lambda site-specific recombination complexes
    • Thompson, J. F. and Landy, A. (1988) Empirical estimation of protein-induced DNA bending angles: applications to lambda site-specific recombination complexes. Nucleic Acids Res. 16, 9687-9705
    • (1988) Nucleic Acids Res. , vol.16 , pp. 9687-9705
    • Thompson, J.F.1    Landy, A.2
  • 41
    • 0028046675 scopus 로고
    • Cloning and characterization of seven human forkhead proteins: Binding site specificity and DNA bending
    • Pierrou, S., Hellqvist, M., Samuelsson, L., Enerback, S. and Carlsson, P. (1994) Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending. EMBO J. 13, 5002-5012
    • (1994) EMBO J. , vol.13 , pp. 5002-5012
    • Pierrou, S.1    Hellqvist, M.2    Samuelsson, L.3    Enerback, S.4    Carlsson, P.5
  • 42
    • 0036606444 scopus 로고    scopus 로고
    • Retinoic acid receptor-related orphan receptor (ROR) α4 is the predominant isoform of the nuclear receptor RORα in the liver and is up regulated by hypoxia in HepG2 human hepatoma cells
    • Chauvet, C., Bois-Joyeux, B. and Danan, J.-L. (2002) Retinoic acid receptor-related orphan receptor (ROR) α4 is the predominant isoform of the nuclear receptor RORα in the liver and is up regulated by hypoxia in HepG2 human hepatoma cells. Biochem. J. 364, 449-456
    • (2002) Biochem. J. , vol.364 , pp. 449-456
    • Chauvet, C.1    Bois-Joyeux, B.2    Danan, J.-L.3
  • 43
    • 0034698040 scopus 로고    scopus 로고
    • Transcriptional stimulation by hepatocyte nuclear factor-6. Target-specific recruitment of either CREB-binding protein (CBP) or p300/CBP-associated factor (p/CAF)
    • Lannoy, V. J., Rodolosse, A., Pierreux, C. E., Rousseau, G. G. and Lemaigre, F. P. (2000) Transcriptional stimulation by hepatocyte nuclear factor-6. Target-specific recruitment of either CREB-binding protein (CBP) or p300/CBP-associated factor (p/CAF). J. Biol. Chem. 275, 22098-22103
    • (2000) J. Biol. Chem. , vol.275 , pp. 22098-22103
    • Lannoy, V.J.1    Rodolosse, A.2    Pierreux, C.E.3    Rousseau, G.G.4    Lemaigre, F.P.5
  • 44
    • 0033556268 scopus 로고    scopus 로고
    • Exogenous expression of a dominant negative RORα1 vector in muscle cells impairs differentiation: RORα1 directly interacts with p300 and myoD
    • Lau, P., Bailey, P., Dowhan, D. H. and Muscat, G. E. (1999) Exogenous expression of a dominant negative RORα1 vector in muscle cells impairs differentiation: RORα1 directly interacts with p300 and myoD. Nucleic Acids Res. 27, 411-420
    • (1999) Nucleic Acids Res. , vol.27 , pp. 411-420
    • Lau, P.1    Bailey, P.2    Dowhan, D.H.3    Muscat, G.E.4
  • 46
    • 0034602408 scopus 로고    scopus 로고
    • Synergistic action of hepatocyte nuclear factors 3 and 6 on CYP2C12 gene expression and suppression by growth hormone-activated STAT5b. Proposed model for female specific expression of CYP2C12 in adult rat liver
    • Delesque-Touchard, N., Park, S. H. and Waxman, D. J. (2000) Synergistic action of hepatocyte nuclear factors 3 and 6 on CYP2C12 gene expression and suppression by growth hormone-activated STAT5b. Proposed model for female specific expression of CYP2C12 in adult rat liver. J. Biol. Chem. 275, 34173-34182
    • (2000) J. Biol. Chem. , vol.275 , pp. 34173-34182
    • Delesque-Touchard, N.1    Park, S.H.2    Waxman, D.J.3
  • 47
    • 0034796563 scopus 로고    scopus 로고
    • Regulatory mechanisms controlling human hepatocyte nuclear factor 4α gene expression
    • Hatzis, P. and Tatianidis, I. (2001) Regulatory mechanisms controlling human hepatocyte nuclear factor 4α gene expression. Mol. Cell. Biol. 21, 7320-7330
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 7320-7330
    • Hatzis, P.1    Tatianidis, I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.