Transcriptional cooperativity: Bending over backwards and doing the flip

Structure

Volumn 6, Issue 5, 1998, Pages 549-554

  Kerppola, Tom K ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0032524123     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(98)00057-4     Document Type: Article

References (24)

1. Tan, S. & Richmond, T.J. (1998). Crystal structure of the yeast MATα2/MCM1/DNA ternary complex. Nature 391, 660.
2. Chen, L., Glover, J.N.M., Hogan, P.G., Rao, A. & Harrison, S.C. (1998). Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA. Nature 392, 42-48.
3. Shaw, K. T.-Y., et al. & Hogan, P. G. (1995). Immunosuppressive drugs prevent a rapid dephosphorylation of transcription factor NFAT1 in stimulated immune cells. Proc. Natl. Acad. Sci. USA 92, 11205-11209.
4. Xanthoudakis, S., et al., & Rao, A. (1996). An enhanced immune response in mice lacking the transcription factor NFAT1. Science 272, 892-895.
5. Kiani, A., Viola, J.P.B., Lichtman, A.M. & Rao, A. (1997). Down-regulation of IL-4 gene transcription and control of the TH2 cell differentiation by a mechanism involving NFAT1. Immunity 7, 849-860.
6. Yoshida, H., et al., & Mak, T.W. (1998). The transcription factor NF-ATc1 regulates lymphocyte proliferation and Th2 cytokine production. Immunity 8, 115-124.
7. de la Pompa, J.L., et al., & Mak, T.W. (1998). Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum. Nature 392, 182-186.
8. Ranger, A.M., et al., & Glimcher, L.H. (1998). The transcription factor NF-ATc is essential for cardiac valve formation. Nature 392, 186-190.
9. Robertson, L.M., et al., & Curran, T. (1995). Regulation of c-fos expression in transgenic mice requires multiple interdependent transcription control elements. Neuron 14, 241-252.
10. Jain, J., et al. & Rao, A. (1994). Normal peripheral T-cell function in c-Fos-deficient mice. Mol. Cell Biol. 14, 1566-1574.
11. Jain, J., Burgeon, E., Badalian, T.M., Hogan, P.G. & Rao, A. (1995). A similar DNA-binding motif in NFAT family proteins and the Rel homology region. J. Biol. Chem. 270, 4138-4145.
12. Chen, Y.-Q., Ghosh, S. & Ghosh, G. (1998). A novel DNA recognition mode by the NF-κB p65 homodimer. Nat. Struct. Biol. 5, 67-73.
13. Glover, J.N. & Harrison, S.C. (1995). Crystal structure of the heterodimeric bZIP transcription factor c- Fos-c-Jun bound to DNA. Nature 373, 257-261.
14. Diebold, R.J., Rajaram, N., Leonard, D.A. & Kerppola, T.K. (1998). Molecular basis of cooperative DNA bending and oriented heterodimer binding in the NFAT1-Fos-Jun-ARRE2 complex. Proc. Natl Acad. Sci. USA, in press.
15. Kerppola, T.K. & Curran, T. (1991). Fos-Jun heterodimers and Jun homodimers bend DNA in opposite orientations: Implications for transcription factor cooperativity. Cell 66, 317-326.
16. Kerppola, T.K. & Curran, T. (1991). DNA bending by Fos and Jun: The flexible hinge model. Science 254, 1210-1214.
17. Leonard, D.A., Rajaram, N. & Kerppola, T.K. (1997). Structural basis of DNA bending and oriented heterodimer binding by Fos and Jun. Proc. Natl. Acad. Sci. USA 94, 4913-4918.
18. Zhou, P., Sun, L.J., Dotsch, V., Wagner, G. & Verdine, G.L. (1998). Solution structure of the core NFATC1/DNA complex. Cell 92, 687-696.
19. Rajaram, N. & Kerppola, T.K. (1997). DNA bending by Fos-Jun and the orientation of heterodimer binding depend on the sequence of the AP-1 site. EMBO J 16, 2917-2925.
20. Chen, L., et al., & Verdine, G. L. (1995). Only one of the two DNA-bound orientations of AP-1 found in solution cooperates with NFATp. Curr. Biol 5, 882-889.
21. Giese, K., Kingsley, C., Kirshner, J. R. & Grosschedl, R. (1995). Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions. Genes Dev. 9, 995-1008.
22. Kim, T.K. & Maniatis, T. (1998). The mechanism of transcriptional synergy of an in vitro assembled interferon-β enhanceosome. Mol. Cell 1, 119-129.
23. McCaffrey, P.G., et al., & Rao, A. (1993). Isolation of the cyclosporinsensitive T cell transcription factor NFATp. Science 262, 750-754.
24. Luo, C., Burgeon, E. & Rao, A. (1996). Mechanisms of transactivation by nuclear factor of activated T cells-1. J. Exp. Med. 184, 141-147.