Regulation of local angiotensin II formation in the human heart in the presence of interstitial fluid: Inhibition of chymase by protease inhibitors of interstitial fluid and of angiotensin-converting enzyme by ANG-(1-9) formed by heart carboxypeptidase A-like activity

Circulation

Volumn 95, Issue 6, 1997, Pages 1455-1463

  Kokkonen, Jorma O ^a   Saarinen, Juhani ^a   Kovanen, Petri T ^a  

^a WIHURI RESEARCH INSTITUTE   (Finland)

Author keywords

angiotensin; heart failure; myocardium; remodeling

Indexed keywords

ANGIOTENSIN; APROTININ; CAPTOPRIL; CHYMASE; CHYMOSTATIN; DIPEPTIDYL CARBOXYPEPTIDASE; EDETIC ACID; LISINOPRIL; PROTEINASE INHIBITOR;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME KINETICS; HUMAN; HUMAN CELL; HUMAN TISSUE; INHIBITION KINETICS; INTERSTITIAL FLUID; PRIORITY JOURNAL; PROTEINASE INHIBITION; REGULATORY MECHANISM; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; TISSUE HOMOGENATE;

EID: 0030971415     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.95.6.1455     Document Type: Article

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