Chymase in exocytosed rat mast cell granules effectively proteolyzes apolipoprotein AI-containing lipoproteins, so reducing the cholesterol efflux-inducing ability of serum and aortic intimal fluid

Journal of Clinical Investigation

Volumn 97, Issue 10, 1996, Pages 2174-2182

  Lindstedt, Leena ^a   Lee, Miriam ^a,c   Castro, Graciela R ^b   Fruchart, Jean Charles ^b   Kovanen, Petri T ^a  

^a WIHURI RESEARCH INSTITUTE   (Finland)

^b INSTITUT PASTEUR DE LILLE   (France)

^c UNIVERSITY OF HAVANA   (Cuba)

Author keywords

apolipoprotein AI; cellular cholesterol efflux; foam cells; mast cells; neutral proteases

Indexed keywords

APOLIPOPROTEIN A1; CHYMASE; HIGH DENSITY LIPOPROTEIN; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; PROTEINASE INHIBITOR;

ANIMAL CELL; AORTA INTIMA; ARTICLE; ATHEROGENESIS; CELL GRANULE; CHOLESTEROL TRANSPORT; ENZYME ISOLATION; EXOCYTOSIS; FOAM CELL; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MACROPHAGE; MALE; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; SERUM;

EID: 0029889948     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118658     Document Type: Article

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