The mitogen-activated protein kinase phosphatase-3 N-terminal noncatalytic region is responsible for tight substrate binding and enzymatic specificity

Journal of Biological Chemistry

Volumn 273, Issue 15, 1998, Pages 9323-9329

  Muda, Marco ^a,d   Theodosiou, Aspasia ^b   Gillieron, Corine ^a   Smith, Anna ^b   Chabert, Christian ^a   Camps, Montserrat ^a   Boschert, Ursula ^a   Rodrigues, Nanda ^c   Davies, Kay ^c   Ashworth, Alan ^b   Arkinstall, Steve ^a  

^a SERONO PHARMACEUTICAL RES INSTITUTE   (Switzerland)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATASE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; ENZYME BINDING; ENZYME INACTIVATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; ENZYME SUBUNIT; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CATALYSIS; CLONING, MOLECULAR; COS CELLS; ESCHERICHIA COLI; GLUTATHIONE TRANSFERASE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN-TYROSINE-PHOSPHATASE; RECOMBINANT FUSION PROTEINS; SUBSTRATE SPECIFICITY; TRANSFECTION;

ANIMALIA; ESCHERICHIA COLI;

EID: 0032502671     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.15.9323     Document Type: Article

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