Gender differences in ethanol preference and ingestion in rats: The role of the gonadal steroid environment

Journal of Clinical Investigation

Volumn 101, Issue 12, 1998, Pages 2677-2685

  Almeida, O F X ^a   Shoaib, M ^a,b   Deicke, J ^a   Fischer, D ^a   Darwish, M H ^a   Patchev, V K ^a,c  

^a MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c BAYER PHARMA AG   (Germany)

Author keywords

Addiction; Alcohol; Gender; Sexual differentiation of the brain

Indexed keywords

ALCOHOL; ANDROSTANOLONE; ESTRADIOL; PROGESTERONE; SEX HORMONE;

ALCOHOLISM; ANIMAL EXPERIMENT; ARTICLE; CASTRATION; CONTROLLED STUDY; DRINKING BEHAVIOR; FEMALE; GENDER; MALE; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; RAT; SEX DIFFERENCE;

EID: 0032526262     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI1198     Document Type: Article

References (52)

1. de Lint, J., and W. Schmidt. 1971. The epidemiology of alcoholism. In Biological Basis of Alcoholism. Y. Israel and J. Mardones, editors. John Wiley & Sons. Inc., New York. 423-442.
2. Grant, B.F., T.C. Harford, P. Chou, R. Pickering, D. Dawson, F. Stinson, and J. Noble. 1991. Prevalence of DSM-III-R alcohol abuse and dependence: United States, 1988. Alcohol Health Res. World. 15:15-20.
3. Wilsnack, S.C., and R.W. Wilsnack. 1995. Drinking and problem drinking in US women. In Recent Developments in Alcoholism. Vol. 12. M. Galanter, editor. Plenum Publishing Corp., New York. 29-60.
4. Gomberg, E.S. 1993. Recent developments in alcoholism: gender issues. Recent Dev. Alcohol. 11:95-107.
5. Kidorf, M., A.R. Lang, and W.E. Pelham. 1990. Beverage preference, beverage type and subject gender as determinants of alcohol consumption in the laboratory. J. Stud. Alcohol. 51:331-335.
6. Dawson, D.A., and L.D. Archer. 1993. Relative frequency of heavy drinking and the risk of alcohol dependence. Addiction. 88:1509-1518.
7. Segovia-Riquelme, N., A. Varela, and J. Mardones. 1971. Appetite for alcohol. In Biological Basis of Alcoholism. Y. Israel and J. Mardones, editors. John Wiley & Sons, Inc., New York. 299-334.
8. Eriksson, K. 1968. Genetic selection for voluntary alcohol consumption in albino rats. Science. 159:739-740.
9. Eriksson, K., and P.H. Pikkarainen. 1968. Differences between the sexes in voluntary alcohol consumption and liver ADH-activity in inbred strains of mice. Metabolism. 17:1037-1042.
10. Juarez, J., C. Guzman-Flores, F.R. Ervin, and R.M. Palmour. 1993. Voluntary alcohol consumption in vervet monkeys: individual, sex and age differences. Pharmacol. Biochem. Behav. 46:985-988.
11. Grant, K.A., and C.E. Johanson. 1988. Oral ethanol self-administration in free-feeding rhesus monkeys. Alcohol Clin. Exp. Res. 12:780-784.
12. Moss, H.B., R.J. Salin-Pascual, P. Rathnagiri, D. Goldman, and L. Tamarkin. 1987. Sex differences in ethanol sensitivity and alcohol and aldehyde dehydrogenase activities in the Syrian hamster. Alcohol Drug Res. 7:301-307.
13. Lancaster, F.E., T.D. Brown, K.L. Coker, J.A. Elliott, and S.B. Wren. 1996. Sex differences in alcohol preference and drinking patterns emerge during the early postpubertal period. Alcohol Clin. Exp. Res. 20:1043-1049.
14. Froehlich, J.C. J. Harts, L. Lumeng, and T.-K. Li. 1988. Differences in response to the aversive properties of ethanol in rats selectively bred for oral ethanol preference. Pharmacol. Biochem. Behav. 31:215-222.
15. Gauvin, D.V., and F.A. Holloway. 1992. Ethanol tolerance developed during intoxicated operant performance in rats prevents subsequent ethanol-induced conditioned taste aversion. Alcohol. 9:167-170.
16. Shoaib, M., and O.F.X. Almeida. 1996. Absence of tolerance to the aversive stimulus properties of ethanol following oral ethanol self-administration. Alcohol. 13:175-180.
17. National Institute of Drug Abuse/National Institute on Alcohol Abuse and Alcoholism. 1989. Highlights from the 1987 National Drug and Alcoholism Treatment Unit Survey (NDATUS). NIDA/NIAAA, Rockville, MD. 100 pp.
18. Mezey, E., S. Sharma, L. Rennie, and J.J. Potter. 1992. Sex differences in gastric alcohol dehydrogenase activity of Sprague-Dawley rats. Gastroenterology. 103:1804-1810.
19. Middaugh, L.D., W.F. Frackelton, W.O. Boggan, A. Onofrio, and C.L. Shepherd. 1992. Gender differences in the effects of ethanol on C57BL/6 mice. Alcohol. 9:257-260.
20. Rivier, C. 1993. Female rats release more corticosterone than males in response to alcohol: influence of circulating sex steroids and possible consequences for blood alcohol levels. Alcohol Clin. Exp. Res. 17:854-859.
21. Vaubourdolle, M., J. Guechot, O. Chazouilleres, R.E. Poupon, and J. Giboudeau. 1991. Effect of dihydrotestosterone on the rate of ethanol elimination in healthy men. Alcohol Clin. Exp. Res. 15:238-240.
22. Lammers, S.M., D.E. Mainzer, and M.H. Breteler. 1995. Do alcohol pharmacokinetics in women vary due to the menstrual cycle? Addiction. 90:23-30.
23. Dorgan, J.F., M.E. Reichman, J.T. Judd, C. Brown, C. Longcope. A. Schatzkin, W.S. Campbell, C. Franz, L. Kahle, and P.R. Taylor. 1994. The relation of reported alcohol ingestion to plasma levels of estrogens and androgens in premenopausal women (Maryland, United States). Cancer Causes Control. 5: 53-60.
24. Glenn, S.W. 1993. Sex differences in alcohol-induced brain damage. In Alcohol-induced Brain Damage. NIAAA Research Monograph. 22:195-212.
25. Harper, C.G., N.A. Smith, and J.J. Krill. 1990. The effects of alcohol on the female brain: a neuropathological study. Alcohol. 25:445-448.
26. Norton, R., T. Dwyer, and S. MacMahon. 1987. Alcohol consumption and the risk of alcohol related cirrhosis in women. Br. Med. J. 295:80-82.
27. Lancaster, F.E. 1994. Gender differences in the brain: implications for the study of human alcoholism. Alcohol Clin. Exp. Res. 18:740-746.
28. Li, T.-K., and L. Lumeng. 1984. Alcohol preference and voluntary alcohol intakes of inbred rat strains and the National Institutes of Health heterogenous stock of rats. Alcohol Clin. Exp. Res. 8:485-486.
29. Blanchard, B.A., and S.D. Glick. 1995. Sex differences in mesolimbic dopamine responses to ethanol and relationship to ethanol intake in rats. Rec. Dev. Alcohol 12:231-241.
30. Goy, R.W., and B.S. McEwen. 1980. Sexual differentiation of the brain. MIT Press, Cambridge, MA. 223.
31. Patchev, V.K., S. Hayashi, C. Orikasa, and O.F.X. Almeida. 1995. Implications of estrogen-dependent brain organization for gender differences in hypothalamo-pituitary-adrenal regulation. FASEB (Fed. Am. Soc. Exp. Biol.) J. 9: 419-423.
32. Adams, N. 1995. Sex differences and the effects of tail pinch on ethanol drinking in Maudsley rats. Alcohol. 12:463-468.
33. Lancaster, F.E., and K.S. Spiegel. 1992 Sex differences in pattern of drinking. Alcohol. 9:415-420.
34. van Haaren, F., and K. Anderson. 1994. Sex differences in schedule-induced alcohol consumption. Alcohol. 11:35-40.
35. Cicero, T.J. 1979. A critique of animal models of alcohol self-administration, preference, tolerance and physical dependence. In The Pharmacology of Ethanol. E. Majchrowicz, editor. Plenum Publishing Corp., New York. 553-560.
36. Keane, B., and B.E. Leonard. 1989. Rodent models of alcoholism: a review. Alcohol. 24:299-309.
37. Neill, J.C., A.M. Domeney, and B. Costall. 1994. Initiation and maintenance of ethanol oral self-administration in female Sprague-Dawley rats. Alcohol. 11:207-218.
38. Altman, J., B.J. Everitt, S. Glautier, A. Markou, D. Null. R. Oretti, G.D. Phillips, and T.W. Robbins. 1996. The biological, social and clinical bases of drug addiction: commentary and debate. Psychopharmacology. 125:285-345.
39. Lisciotto, C.A., J.F. DeBold, and K.A. Miczek. 1990. Sexual differentiation and the effects of alcohol on aggressive behavior in mice. Pharmacol. Biochem. Behav. 35:357-362.
40. Haut, J.S., B.E. Beckwith, T.V. Petros, and S. Russell. 1989. Gender differences in retrieval from long-term memory following acute intoxication with ethanol. Physiol. Behav. 45:1161-1165.
41. Niaura, R.S., P.E. Nathan, W. Frankenstein, A.P. Shapiro. and J. Brick. 1987. Gender differences in acute psychomotor, cognitive, and pharmacokinetic response to alcohol. Addict. Behav. 12:345-356.
42. Linnoila, M., C.W. Erwin, W.P. Cleveland, P.E. Logue. and W.D. Gentry. 1978. Effects of alcohol on psychomotor performance of men and women. J. Stud. Alcohol. 39:745-758.
43. Messiha, F.S. 1985. Neurotoxicological analyses of voluntary alcohol drinking by the rat. Neurobehav. Toxicol. Teratol. 7:155-159.
44. Tabakoff, B., and P.L. Hoffman. 1996. Alcohol addiction: an enigma among us. Neuron. 16:909-912.
45. Almeida, O.F.X., V. Canoine, S. Ali, F. Holsboer, and V.K. Patchev. 1997. Activational effects of gonadal steroids on hypothalmo-pituitary-adrenal regulation in the rat disclosed by response to dexamethasone suppression. J. Neuroendocrinol. 9:129-134.
46. Zaphiropoulos, P.G., A. Mode, G. Norstedt, and J.-Å. Gustafsson. 1989. Regulation of sexual differentiation in drug and steroid metabolism. Trends Pharmacol. Sci. 10:149-153.
47. van Haaren, F., 1995. Experimental analysis of sex differences in alcohol consumption. In Stress, Gender, and Alcohol-Seeking Behavior. NIAAA Research Monograph. 29:293-310.
48. Emanuele, M.A., M.M. Halloran, S. Uddin, J.J. Tentler, N.V. Emanuele, A.M. Lawrence, and M.R. Kelley. 1993. The effects of alcohol on the neuroendocrine control of reproduction. In Alcohol and the Endocrine System. NIAAA Research Monograph. 23:89-166.
49. Mello, N.K., J.J. Mendelson, and S.K. Teoh. 1993. An overview of the effects of alcohol on neuroendocrine function in women. Alcohol and the endocrine system. NIAAA Research Monograph. 23:139-169.
50. Teschke, R., and B. Wiese. 1982. Sex dependency of hepatic alcohol metabolizing enzymes. J. Endocrinol. Invest. 5:243-250.
51. Cole-Harding, S., and J. Wilson. 1987. Ethanol metabolism in men and women. J. Stud. Alcohol. 48:380-387.
52. Mello, N.K., J.H. Mendelson, and B.W. Lex. 1990. Alcohol use and premenstrual symptoms in social drinkers. Psychopharmacology. 101:448-455.