Renoprotection by ACE inhibition or aldosterone blockade is blood pressure-dependent

Hypertension

Volumn 41, Issue 2, 2003, Pages 201-206

  Griffin, Karen A ^a   Abu Amarah, Isam ^a   Picken, Maria ^a   Bidani, Anil K ^a  

^a LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Autoregulation; Hypertension, renal; Nephrosclerosis; Rats, stroke prone SHR

Indexed keywords

ALDOSTERONE ANTAGONIST; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; SPIRONOLACTONE; TAP WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE MEASUREMENT; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME INHIBITION; FLUID INTAKE; HISTOPATHOLOGY; HYPERTENSION; KIDNEY INJURY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SCORING SYSTEM; SPONTANEOUSLY HYPERTENSIVE RAT; SUSTAINED RELEASE PREPARATION; SYSTOLIC BLOOD PRESSURE; TELEMETRY; URINARY EXCRETION;

ALDOSTERONE ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; BLOOD PRESSURE; DELAYED-ACTION PREPARATIONS; ENALAPRIL; HYPERTENSION; KIDNEY; LINEAR MODELS; MALE; PROTEINURIA; RATS; RATS, INBRED SHR; SODIUM CHLORIDE; SPIRONOLACTONE; TIME FACTORS;

EID: 0037313147     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.0000049881.25304.73     Document Type: Article

References (49)

1. Okamoto K, Yamori Y, Nagaoka A. Establishment of the stroke-prone spontaneously hypertensive rat (SHR). Circ Res. 1974;34/35(suppl 1):143-153.
2. Nagaoka A, Iwatsuka H, Suzuoki Z, Okamoto K. Genetic predisposition to stroke in spontaneously hypertensive rats. Am J Physiol. 1976;230:1354-1359.
3. Smeda JS. Hemorrhagic stroke development in spontaneously hypertensive rats fed a North-American, Japanese-style diet. Stroke. 1989;20:1212-1218.
4. Volpe M, Camargo MJF, Mueller FB, Campbell WB Jr, Sealey JE, Pecker MS, Sosa RE, Laragh JH. Relationship of plasma renin to end organ damage and to protection of K+ feeding in stroke-prone hypertensive rats. Hypertension. 1990;15:318-326.
5. Rubatuu S, Volpe M, Kreutz R, Ganten U, Ganten D, Lindpaintner K. Chromosomal mapping of quantitative trait loci contributing to stroke in a rat model of complex human disease. Nature Genet. 1996;13:429-432.
6. Dominiczak AF, Clark JS, Jeffs B, Anderson NH, Negrin CD, Lee WK, Brosnan MJ. Genetics of experimental hypertension. J Hypertens. 1998;16:1859-1869.
7. Tanaka M, Schmidlin O, Olson JL, Yi S-L, Morris RC Jr. Chloride-sensitive renal microangiopathy in the stroke-prone spontaneously hypertensive rat. Kidney Int. 2001;59:1066-1076.
8. Griffin KA, Churchill PC, Picken M, Webb RC, Kurtz TW, Bidani AK. Differential salt-sensitivity in the pathogenesis of renal damage in SHR and stroke prone SHR. Am J Hypertens. 2001;14:311-320.
9. Churchill PC, Churchill MC, Griffin KA, Picken M, Webb RC, Kurtz TW, Bidani AK. Increased genetic susceptibility to renal damage in the stroke-prone spontaneously hypertensive rat. Kidney Int. 2002;61:1794-1800.
10. Stier CT Jr, Benter IF, Ahmad S, Zuo H, Selig N, Roethel S, Levine S, Itskovitz HD. Enalapril prevents stroke and kidney dysfunction in salt-loaded stroke-prone spontaneously hypertensive rats. Hypertension. 1989;13:115-121.
11. Stier CT Jr, Adler AL, Levine S, Chander PN. Stroke prevention by losartan in stroke-prone spontaneously hypertensive rats. J Hypertens. 1993;11:537-542.
12. MacLeod AB, Vasdev S, Smeda JS. The role of blood pressure and aldosterone in the production of hemorrhagic stroke in captopril-treated hypertensive rats. Stroke. 1997;28:1821-1829.
13. Linz W, Becker RHA, Scholkens BA, Wiemer G, Keil M, Langer KH. Nephroprotection by long-term ACE inhibition with ramipril in spontaneously hypertensive stroke prone rats. Kidney Int. 1998;54:2037-2044.
14. Rocha R, Chander PN, Khanna K, Zuckerman A, Stier CT Jr. Mineralocorticoid blockade reduces vascular injury in stroke-prone hypertensive rats. Hypertension. 1998;31:451-458.
15. Rocha R, Chander PN, Zuckerman A, Stier CT Jr. Role of aldosterone in renal vascular injury in stroke-prone hypertensive rats. Hypertension. 1999;33:232-237.
16. Hostetter TH, Rosenberg ME, Ibrahim HN, Juknevicius I. Aldosterone in renal disease. Curr Opin Nephrol Hypertens. 2001;10:105-110.
17. Epstein M. Aldosterone as a mediator of progressive renal disease: pathogenetic and clinical implications. Am J Kidney Diseases. 2001;37:677-688.
18. Bidani AK, Griffin KA, Picken M, Lansky DM. Continuous telemetric BP monitoring and glomerular injury in the rat remnant kidney model. Am J Physiol. 1993;265:F391-F398.
19. Griffin KA, Picken M, Bidani AK. Radiotelemetric BP monitoring, antihypertensives and glomeruloprotection in remnant kidney model. Kidney Int. 1994;46:1010-1018.
20. Griffin KA, Picken MM, Bidani AK. Deleterious effects of calcium channel blockade on pressure transmission and glomerular injury in rat remnant kidneys. J Clin Invest. 1995;96:793-800.
21. Holstein-Rathlou NH, He J, Wagner AJ, Marsh DJ. Patterns of blood pressure variability in normotensive and hypertensive rats. Am J Physiol. 1995;269:R1230-R1239.
22. Churchill PC, Churchill MC, Bidani AK, Griffin KA, Picken M, Pravenec M, Kren E, St. Lezin E, Wang JM, Wang N, Kurtz TW. Genetic susceptibility to hypertension-induced renal damage in the rat: evidence based on kidney-specific genome transfer. J Clin Invest. 1997;100-1373-1382.
23. Shimamura T, Nakajima M. Iwasaki T, Hayasaki Y, Yonetani Y, Iwaki K. Analysis of circadian blood pressure rhythm and target-organ damage in stroke-prone spontaneously hypertensive rats. J Hypertens. 1999;17:211-220.
24. Griffin KA, Picken MM, Bakris GL, Bidani AK. Class differences in the effects of calcium blockers in the rat remnant kidney model. Kidney Int. 1999;55:1849-1860.
25. Bidani AK, Picken MM, Bakris G, Griffin KA. Lack of evidence of BP independent protection by renin-angiotensin system blockade after renal ablation. Kidney Int. 2000;57:1651-1661.
26. Fry JC. Biological data analysis: a practical approach. In: Rickwood D, Hames BD, eds. The Principal Approach Series. New York: OIRL Press at Oxford University Press, Inc: 1993.
27. Xu Q, Liu Y, Gorospe M, Udelsman R, Holdbrook NJ. Acute hypertension activates mitogen-activated protein kinases in arterial wall. J Clin Invest. 1997;97:508-514.
28. Calhoun DA, Sutao Z, Wyss MJ, Oparil S. Diurnal blood pressure variation and dietary salt in spontaneously hypertensive rats. Hypertension. 1994;24:1-7.
29. Webb RL, Barclay BW, Navarrete AE, Wosu NJ, Sahota P. Protective effects of valsartan and benazeprilat in salt-loaded stroke-prone spontaneously hypertensive rats. Clin Exp Hypertens. 1998;20:775-793.
30. Yamori Y, Horie R, Tanase H, Fujiwara K, Nara Y, Lovenberg W. Possible role of nutritional factors in the incidence of cerebral lesions in stroke-prone spontaneously hypertensive rats. Hypertension. 1989;6:49-53.
31. Tanaka M, Schmidlin O, Yi S-L, Bollen AW, Morris RC Jr. Genetically determined chloride-sensitive hypertension and stroke. Proc Natl Acad Sci U S A. 1997;94:14748-14752.
32. Shibota M, Nagaoka A, Shino A, Fujita T. Renin-angiotensin system in stroke-prone spontaneously hypertensive rats. Am J Physiol. 1979;236: H409-H416.
33. Laragh JH, Sealey JE. Renin-angiotensin-aldosterone system and the renal regulation of sodium, potassium and blood pressure homeostasis. In: Windhager EE, ed. Handbook of Physiology. New York: Oxford University Press; 1992:1409-1541.
34. Guyton AC, Hall JE, Coleman TG, Manning RD Jr, Norman RA Jr. The dominant role of the kidneys in long-term arterial pressure regulation in normal and hypertensive states. In: Laragh JH, Brenner BM, eds. Hypertension: Pathophysiology, Diagnosis, and Management. New York: Raven Press; 1995:1311-1326.
35. Byron FB. The Hypertensive Vascular Crisis: An Experimental Study (Heinemann Monograph). London: Pitman Press; 1969.
36. Ogata J, Fujishiima M, Tamaki K, Nakatomi Y, Ishitsuka T, Omae T. Stroke-prone spontaneously hypertensive rats as an experimental model of malignant hypertension: a pathological study. Virchows Arch A. 1982;394:185-194.
37. Bidani AK, Griffin KA, Plott W, Schwartz MM. Renal ablation acutely transforms 'benign' hypertension to 'malignant' nephrosclerosis in hypertensive rats. Hypertension. 1994;24:309-316.
38. Olson JL. Hypertension: essential and secondary forms. In: Jennette JC, Olson JL, Schwartz MM, Silva FG, eds. Heptinstall's Pathology of the Kidney. 5th ed. Vol 2. Philadelphia, Pa: Lippincott-Raven; 1998:943-1002.
39. Navar LG. Renal autoregulation: perspectives from whole kidney and single nephron studies. Am J Physiol. 1978;234:F357-F370.
40. Bidani A, Schwartz MM, Lewis EJ. Renal autoregulation and vulnerability to hypertensive injury in remnant kidney. Am J Physiol. 1987;252:F1003-F1010.
41. Bidani AK, Griffin KA. Long-term renal consequences of hypertension for normal and diseased kidneys. Curr Opin Nephrol Hypertens. 2002;11:73-80.
42. Hill GS. Studies on the pathogenesis of hypertensive vascular disease: effects of high pressure intra-arterial injection in rats. Circ Res. 1970;27:657-668.
43. Belin LJ, Goldby FS. High arterial pressure versus humoral factors in the pathogenesis of the vascular lesions of malignant hypertension: the case for pressure alone. Clin Sci Mol Med. 1977;52:111-117.
44. Ledingham JM. The vascular fault in hypertension: Byrom's work revisited. In: Laragh JH, Brenner BM, eds. Hypertension Pathophysiology Diagnosis and Management. 2nd ed. Chapter 3. New York: Raven Press: 1995:37-53.
45. Helmchen U, Kneissler U, Bohle RM, Reher A, Groene HJ. Adaptation and decompensation of intrarenal small arteries in experimental hypertension. J Cardiovasc Pharmacol. 1984;6:S696-S705.
46. Stradgaard S, Paulson OB. Cerebral blood flow and its pathophysiology in hypertension. Am J Hypertens. 1989;2:486-492.
47. Iversen BM, Sekse I, Ofstad J. Resetting of renal blood flow autoregulation in spontaneously hypertensive rats. Am J Physiol. 1987;252:F480-F486.
48. Griffin KA, Picken M, Bakris GL, Bidani AK. Comparative effects of selective T- and L-type calcium channel blockers in the remnant kidney model. Hypertension. 2001;37:1268-1272.
49. Joint National Committee on Prevention. Detection, Evaluation, and Treatment of High Blood Pressure. The sixth Report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure (JNC VI). Arch Intern Med. 1997;157:2413-2446.