The neural cell adhesion molecule (NCAM) in development and plasticity of the nervous system

Experimental Gerontology

Volumn 33, Issue 7-8, 1998, Pages 853-864

  Ronn L C B ^a   Hartz, B P ^a   Bock, E ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Cell adhesion; Learning; Long term potentiation; NCAM; Neurite extension; Regeneration; Signal transduction; Synaptic plasticity

Indexed keywords

NERVE CELL ADHESION MOLECULE;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; CONFERENCE PAPER; DRUG RECEPTOR BINDING; EXTRACELLULAR MATRIX; FASCICULATION; LEARNING; LONG TERM POTENTIATION; NERVE CELL PLASTICITY; NERVE REGENERATION; NERVOUS SYSTEM FUNCTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION;

AGING; ANIMALS; ANIMALS, NEWBORN; EMBRYONIC AND FETAL DEVELOPMENT; FETUS; NERVOUS SYSTEM; NEURAL CELL ADHESION MOLECULES; NEURONAL PLASTICITY;

EID: 0032434753     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0531-5565(98)00040-0     Document Type: Conference Paper

References (93)

1. Acheson A., Sunshine J.L., Rutishauser U. NCAM polysialic acid can regulate both cell-cell and cell-substrate interactions. J. Cell Biol. 114:1991;143-153.
2. Alexinsky T., Przybyslawski J., Mileusnic R., Rose S.P., Sara S.J. Antibody to day-old chick brain glycoprotein produces amnesia in adult rats. Neurobiol. Learn. Mem. 67:1997;14-20.
3. Angata K., Nakayama J., Fredette B., Chong K., Ranscht B., Fukuda M. Human STX polysialyltransferase forms the embryonic form of the neural cell adhesion molecule. Tissue-specific expression, neurite outgrowth, and chromosomal localization in comparison with another polysialyltransferase, PST. J. Biol. Chem. 272:1997;7182-7190.
4. Bailey C.H., Chen M., Keller F., Kandel E.R. Serotonin-mediated endocytosis of apCAM An early step of learning-related synaptic growth in Aplysia . Science. 256:1992;645-649.
5. Becker C.G., Artola A., Gerardy-Schahn R., Becker T., Welzl H., Schachner M. The polysialic acid modification of the neural cell adhesion molecule is involved in spatial learning and hippocampal long-term potentiation. J. Neurosci. Res. 45:1996;143-152.
6. Beggs H.E., Soriano P., Maness P.F. NCAM-dependent neurite outgrowth is inhibited in neurons from Fyn-minus mice. J. Cell Biol. 127:1994;825-833.
7. Beggs H.E., Baragona S.C., Hemperly J.J., Maness P.F. NCAM140 interacts with the focal adhesion kinase p125fak and the SRC-related tyrosine kinase p59fyn. J. Biol. Chem. 272:1997;8310-8319.
8. Bock E., Edvardsen K., Gibson A., Linnemann D., Lyles J.M., Nybroe O. Characterization of soluble forms of NCAM. FEBS Lett. 225:1987;33-36.
9. Brümmendorf T., Rathjen F.G. Cell adhesion molecules 1 Immunoglobulin superfamily . Prot. Profile. 2:1995;963-1108.
10. Cole G.J., Loewy A., Glaser L. Neuronal cell-cell adhesion depends on interactions of N-CAM with heparin-like molecules. Nature. 320:1986;445-447.
11. Cremer H., Lange R., Christoph A., Plomann M., Vopper G., Roes J., Brown R., Baldwin S., Kraemer P., Scheff S., Baerhels D., Rajewsky K., Wille W. Inactivation of the N-CAM gene in mice results in size reduction of the olfactory bulb and deficiets in spatial learning. Nature. 367:1994;455-459.
12. Cremer H., Chazal G., Goridis C., Represa A. NCAM is essential for axonal growth and fasciculation in the hippocampus. Mol. Cell. Neurosci. 8:1997;323-335.
13. Daston M.M., Bastmeyer M., Rutishauser U., O'Leary D.D. Spatially restricted increase in polysialic acid enhances corticospinal axon branching related to target recognition and innervation. J. Neurosci. 16:1996;5488-5497.
14. Doherty P., Ashton S.V., Moore S.E., Walsh F.S. Morphoregulatory activities of NCAM and N-cadherin can be accounted for by G protein-dependent activation of L- and N-type neuronal calcium-channels. Cell. 67:1991;21-33.
15. Doherty P., Moolenaar C.E., Ashton S.V., Michalides R.J., Walsh F.S. The VASE exon downregulates the neurite growth-promoting activity of NCAM 140. Nature. 356:1992;791-793.
16. Doherty P., Walsh F.S. CAM-FGF receptor interactions A model for axonal growth . Mol. Cell. Neurosci. 8:1996;99-111.
17. Doyle E., Nolan P.M., Bell R., Regan C.M. Intraventricular infusions of anti-neural cell adhesion molecules in a discrete posttraining period impair consolidation of a passive avoidance response in the rat. J. Neurochem. 59:1992;1570-1573.
18. Doyle E., Nolan P.M., Bell R., Regan C.M. Hippocampal NCAM180 transiently increases sialylation during the aquisition and consolidation of a passive avoidance response in the adult rat. J. Neurosci. Res. 31:1992;513-523.
19. Eckhardt M., Muhlenhoff M., Bethe A., Koopman J., Frosch M. Molecular characterization of eukaryotic polysialyltransferase-1. Nature. 373:1995;715-718.
20. Edelman G.M., Chuong C.M. Embryonic to adult conversion of neural cell adhesion molecules in normal and staggerer mice. Proc. Natl. Acad. Sci. USA. 79:1982;7036-7040.
21. Edelmann G.M., Crossin K.L. Cell adhesion molecules Implications for a molecular histology . Annu. Rev. Biochem. 60:1991;155-190.
22. Fazeli M.S., Breen K., Errington M.L., Bliss T.V.P. Increase in extracellular NCAM and amyloid precursor protein following induction of long-term potentiation in the dentate gyrus of anaesthetized rats. Neurosci. Lett. 169:1994;77-80.
23. Fields R.D., Itoh K. Neural cell adhesion molecule in activity-dependent development and synaptic plasticity. Trends Neurosci. 19:1996;473-480.
24. Fox G.B., O'Connell A.W., Murphy K.J., Regan C.M. Memory consolidation induces a transient and time-dependent increase in the frequency of neural cell adhesion molecule polysialylated cells in the adult rat hippocampus. J. Neurochem. 65:1995;2796-2799.
25. Fraser S.E., Murray B.A., Chuong C.M., Edelman G.M. Alteration of the retinotectal map in Xenopus by antibodies to neural cell adhesion molecules. Proc. Natl. Acad. Sci. USA. 81:1984;4222-4226.
26. Gegelashvili G., Andersson A.M., Schousboe A., Bock E. Cyclic AMP regulates NCAM expression and phosphorylation in cultured mouse astrocytes. Eur. J. Cell Biol. 62:1993;343-351.
27. Grumet M., Flaccus A., Margolis R.U. Functional characterization of chondroitin sulfate proteoglycans of brain Interactions with neurons and neural cell adhesion molecules . J. Cell Biol. 120:1993;815-824.
28. Hall H., Walsh F.S., Doherty P. A role for the FGF receptor in the axonal growth response stimulated by cell adhesion molecules. Cell Adhes. Commun. 3:1996;441-450.
29. Holden H.M., Ito M., Hartshorne D.J., Rayment I. X-ray structure determination of telokin, the C-terminal domain of myosin light chain kinase, at 2.8 A resolution. J. Mol. Biol. 227:1992;840-851.
30. Horstkorte R., Schachner M., Magyar J.P., Vorherr T., Schmitz B. The fourth immunoglobulin-like domain of NCAM contains a carbohydrate recognition domain for oligomannosidic glycans implicated in association with L1 and neurite outgrowth. J. Cell Biol. 121:1993;1409-1421.
31. Joliot A.H., Triller A., Volovitch M., Pernelle C., Prochiantz A. Alpha-2,8-Polysialic acid is the neuronal surface receptor of antennapedia homeobox peptide. New Biol. 3:1991;1121-1134.
32. Kadmon G., Kowitz A., Altevogt P., Schachner M. Functional cooperation between the neural adhesion molecules L1 and N-CAM is carbohydrate dependent. J. Cell Biol. 110:1990;209-218.
33. Kadmon G., Kowitz A., Altevogt P., Schachner M. The neural cell adhesion molecule N-CAM enhances L1-dependent cell-cell interactions. J. Cell Biol. 110:1990;193-208.
34. Kiselyov V.V., Berezin V., Maar T.E., Soroka V., Edvardsen K., Schousboe A., Bock E. The first Ig-like NCAM domain is involved in double reciprocal interaction with the second Ig-like NCAM domain and in heparin binding. J. Biol. Chem. 272:1996;10125-10134.
35. Kiss J.Z., Wang C., Olive S., Rougon G., Lang J., Baetens D., Harry D. Activity-dependent mobilization of the adhesion molecule polysialic NCAM to the cell surface of neurons and endocrine cells. EMBO J. 13:1994;5284-5292.
36. Krog L., Bock E. Glycosylation of neural cell adhesion molecules of the immunoglobulin superfamily. APMIS Suppl. 27:1992;53-70.
37. Landmesser L., Dahm L., Tang J.C., Rutishauser U. Polysialic acid as a regulator of intramuscular nerve branching during embryonic development. Neuron. 4:1990;655-667.
38. Linnemann D., Lyles J.M., Bock E. A developmental study of the biosynthesis of the neural cell adhesion molecule. Dev. Neurosci. 7:1985;230-238.
39. Lüthi A., Laurent J.P., Figurov A., Muller D., Schachner M. Hippocampal long-term potentiation and neural cell adhesion molecules L1 and NCAM. Nature. 372:1994;777-779.
40. Martersteck C.M., Kedersha N.L., Drapp D.A., Tsui T.G., Colley K.J. Unique alpha 2, 8-polysialylated glycoproteins in breast cancer and leukemia cells. Glycobiology. 6:1996;289-301.
41. Mayford M., Barzilai A., Keller F., Schacher S., Kandel E.R. Modulation of an NCAM-related adhesion molecule with long-term synaptic plasticity in Aplysia. Science. 256:1992;638-644.
42. Mileusnic R., Rose S.P., Lancashire C., Bullock S. Characterisation of antibodies specific for chick brain neural cell adhesion molecules which cause amnesia for a passive avoidance task. J. Neurochem. 64:1995;2598-2606.
43. Milev P., Maurel P., Haring M., Margolis R.K., Margolis R.U. TAG-1/axonin-1 is a high-affinity ligand of neurocan, phosphacan/protein-tyrosine phosphatase-zeta/beta, and N-CAM. J. Biol. Chem. 271:1996;15716-15723.
44. Miragall F., Kadmon G., Husmann M., Schachner M. Expression of cell adhesion molecules in the olfactory system of the adult mouse Presence of the embryonic form of N-CAM . Dev. Biol. 129:1988;516-531.
45. Mühlenhoff M., Eckhardt M., Bethe A., Frosch M., Gerardy-Schahn R. Autocatalytic polysialylation of polysialyltransferase-1. EMBO J. 15:1996;6943-6950.
46. Muller D., Wang C., Skibo G., Toni N., Cremer H., Calaora V., Rougon G., Kiss J.Z. PSA-NCAM is required for activity-induced synaptic plasticity. Neuron. 17:1996;413-422.
47. Murphy K.J., O'Connell A.W., Regan C.M. Repetitive and transient increases in hippocampal neural cell adhesion molecule polysialylation state following multitrial spatial training. J. Neurochem. 67:1996;1268-1274.
48. Murray B.A., Hemperly J.J., Prediger E.A., Edelman G.M., Cunningham B.A. Alternatively spliced mRNAs code for different polypeptide chains of the chicken neural cell adhesion molecule (N-CAM). J. Cell Biol. 102:1986;189-193.
49. Nakayama J., Fukuda M.N., Fredette B., Ranscht B., Fukuda M. Expression cloning of a human polysialyltransferase that forms the polysialylated neural cell adhesion molecule present in emryonic brain. Proc. Natl. Acad. Sci. USA. 922:1995;7031-7035.
50. Nakayama J., Fukuda M. A human polysialyltransferase directs in vitro synthesis of polysialic acid. J. Biol. Chem. 271:1996;1829-1832.
51. Noble M., Albrechtsen M., Moller C., Lyles J., Bock E., Goridis C., Rutishauser U. Glial cells express N-CAM/D2-CAM-like polypeptides in vitro. Nature. 316:1985;725-728.
52. O'Connell A.W., Fox G.B., Barry T., Foley A.G., Murphy K.J., Fichera G., Kelly J., Regan C.M. Spatial learning activates neural cell adhesion molecule polysialylation in a cortico-hippocampal pathway within the medial temporal lobe. J. Neurochem. 68:1997;2538-2546.
53. Olsen M., Krog L., Edvardsen K., Skovgaard L.T., Bock E. Intact transmembrane isoforms of the neural cell adhesion molecule are released from the plasma membrane. Biochem. J. 295:1993;833-840.
54. Ono K., Tomasiewicz H., Magnuson T., Rutishauser U. N-CAM mutation inhibits tangential neuronal migration and is phenocopied by enzymatic removal of polysialic acid. Neuron. 13:1994;595-609.
55. Paoloni-Giacobino A., Chen H., Antonarakis S.E. Cloning of a novel human neural cell adhesion molecule gene (NCAM2) that maps to chromosome region 21q21 and is potentially involved in Down syndrome. Genomics. 43:1997;43-51.
56. Pfuhl M., Pastore A. Tertiary structure of an immunoglobulin-like domain from the giant muscle protein titin A new member of the I set . Structure. 3:1995;391-401.
57. Phillips G.R., Krushel L.A., Crossin K.L. Developmental expression of two rat sialyltransferases that modify the neural cell adhesion molecule, N-CAM. Dev. Brain Res. 102:1997;143-155.
58. Probstmeier R., Kuhn K., Schachner M. Binding properties of the neural cell adhesion molecule to different components of the extracellular matrix. J. Neurochem. 53:1989;1794-1801.
59. Rabinowitz J.E., Rutishauser U., Magnuson T. Targeted mutation of Ncam to produce a secreted molecule results in a dominant embryonic lethality. Proc. Natl. Acad. Sci. USA. 93:1996;6421-6424.
60. Rafuse V.F., Landmesser L. Contractile activity regulates isoform expression and polysialylation of NCAM in cultured myotubes Involvement of Ca2+ and protein kinase C . J. Cell Biol. 132:1996;969-983.
61. Ranheim T.S., Edelman G.M., Cunningham B.A. Homophilic adhesion mediated by the neural cell adhesion molecule involves multiple immunoglobulin domains. Proc. Natl. Acad. Sci. USA. 93:1996;4071-4075.
62. Rao Y., Wu X.F., Gariepy J., Rutishauser U., Siu C.H. Identification of a peptide sequence involved in homophilic binding in the neural cell adhesion molecule NCAM. J. Cell Biol. 118:1992;937-949.
63. Rao Y., Wu X.F., Yip P., Gariepy J., Siu C.H. Structural characterization of a homophilic binding site in the neural cell adhesion molecule. J. Biol. Chem. 268:1993;20630-20638.
64. Rao Y., Zhao X., Siu C.H. Mechanism of homophilic binding mediated by the neural cell adhesion molecule NCAM. Evidence for isologous interaction. J. Biol. Chem. 269:1994;27540-27548.
65. Regan C.M., Fox G.B. Polysialylation as a regulator of neural plasticity in rodent learning and aging. Neurochem. Res. 20:1995;593-598.
66. Rønn L.C.B., Bock E., Linnemann D., Jahnsen H. NCAM-antibodies modulate induction of long-term potentiation in rat hippocampal CA1. Brain Res. 677:1995;145-151.
67. Rougon G., Deagostini-Bazin H., Hirn M., Goridis C. Tissue- and developmental stage-specific forms of a neural cell surface antigen linked to differences in glycosylation of a common polypeptide. EMBO J. 1:1982;1239-1244.
68. Rougon G. Structure, metabolism and cell biology of polysialic acids. Eur. J. Cell Biol. 61:1993;197-207.
69. Rutishauser U., Landmesser L. Polysialic acid in the vertebrate nervous system A promoter of plasticity in cell-cell interactions . Trends Neurosci. 19:1996;422-427.
70. Saffell J.L., Williams E.J., Mason I.J., Walsh F.S., Doherty P. Expression of a dominant negative FGF receptor inhibits axonal growth and FGF receptor phosphorylation stimulated by CAMs. Neuron. 18:1997;231-242.
71. Scheidegger E.P., Sternberg L.R., Roth J., Lowe J.B. A human STX cDNA confers polysialic acid expression in mammalian cells. J. Biol. Chem. 270:1995;22685-22688.
72. Scholey A.B., Rose S.P.R., Zamani M.R., Bock E., Schachner M. A role for the neural cell adhesion molecule (NCAM) in a late, consolidating phase of glycoprotein synthesis 6 hours following passive avoidance training of the young chick. Neuroscience. 55:1993;499-509.
73. Schuch U., Lohse M.J., Schachner M. Neural cell adhesion molecules influence second messenger systems. Neuron. 3:1989;13-20.
74. Schuster C.M., Davis G.W., Fetter R.D., Goodman C.S. Genetic dissection of structural and functional components of synaptic plasticity. I. Fasciclin II controls synaptic stabilization and growth. Neuron. 17:1996;641-654.
75. Schuster C.M., Dawis G.W., Fetter R.D., Goodman C.S. Genetic dissection of structural and functional components of synaptic plasticity. II. Fasciclin II controls presynaptic structural plasticity. Neuron. 17:1996;655-667.
76. Seki T., Arai Y. The persistent expression of a highly sialylated NCAM in the dentate gyrus of the adult rat. Neurosci. Res. 12:1991;503-513.
77. Small S.J., Haines S.L., Akeson R.A. Polypeptide variation in an N-CAM extracellular immunoglobulin-like fold is developmentally regulated through alternative splicing. Neuron. 1:1988;1007-1017.
78. Small S.J., Akeson R. Expression of the unique NCAM VASE exon is independently regulated in distinct tissues during development. J. Cell Biol. 111:1990;2089-2096.
79. Sorkin B.C., Hoffman S., Edelman G.M., Cunningham B.A. Sulfation and phosphorylation of the neural cell adhesion molecule, N-CAM. Science. 225:1984;1476-1478.
80. Storms S.D., Kim A.C., Tran B.T., Cole G.J., Murray B.A. NCAM-mediated adhesion of transfected cells to agrin. Cell Adhes. Commun. 3:1996;497-509.
81. Tang J., Rutishauser U., Landmesser L. Polysialic acid regulates growth cone behavior during sorting of motor axons in the plexus region. Neuron. 13:1994;405-414.
82. Thomsen N.K., Soroka V., Jensen P.H., Berezin V., Kiselyov V.V., Bock E. The three-dimensional structure of the first domain of neural cell adhesion molecule. Nat. Struct. Biol. 3:1996;581-585.
83. Tomasiewicz H., Ono K., Yee D., Thompson C., Goridis C., Rutishauser U., Magnuson T. Genetic deletion of a neural cell adhesion molecule variant (N-CAM-180) produces distinct defects in the central nervous system. Neuron. 11:1993;1163-1174.
84. Von Bohlen und Halbach F., Taylor J., Schachner M. Cell type specific effects of the neural cell adhesion molecules L1 and N-CAM on diverse second messenger systems. Eur. J. Neurosci. 4:1992;896-909.
85. Walsh F.S., Dickson G. Generation of multiple N-CAM polypeptides from a single gene. Bioessays. 11:1989;83-88.
86. Wang J.H., Pepinsky R.B., Stehle T., Liu J.H., Karpusas M., Browning B. The crystal structure of an N-terminal two-domain fragment of vascular cell adhesion molecule 1 (VCAM-1) A cyclic peptide based on the domain 1 C-D loop can inhibit VCAM-1-alpha 4 integrin interaction . Proc. Natl. Acad. Sci. USA. 92:1995;5714-5718.
87. Williams A.F., Barclay A.N. The immunoglobulin superfamily - Domains for cell surface recognition. Annu. Rev. Immunol. 6:1988;381-405.
88. Williams D.K., Gannon-Murakami L., Rougon G., Udin S.B. Polysialylated neural cell adhesion molecule and plasticity of ipsilateral connections in Xenopus tectum. Neuroscience. 70:1996;277-285.
89. Williams E.J., Furness J., Walsh F.S., Doherty P. Activation of the FGF receptor underlies neurite outgrowth stimulated by L1, NCAM, and N-cadherin. Neuron. 13:1994;583-594.
90. Yin X., Watanabe M., Rutishauser U. Effect of polysialic acid on the behavior of retinal ganglion cell axons during growth into the optic tract and tectum. Development. 121:1995;3439-3446.
91. Yoshida Y., Kojima N., Kurosawa N., Hamamoto T., Tsuji S. Molecular cloning of Sia alpha 2,3Gal beta 1,4GlcNAc alpha 2,8-sialyltransferase from mouse brain. J. Biol. Chem. 270:1995;14628-14633.
92. Zhu H., Wu F., Schacher S. Changes in expression and distribution of Aplysia cell adhesion molecules can influence synapse formation and elimination in vitro. J. Neurosci. 15:1995;4173-4183.
93. Zuber C., Lackie P.M., Catterall W.A., Roth J. Polysialic acid is associated with sodium channels and the neural cell adhesion molecule N-CAM in adult rat brain. J. Biol. Chem. 267:1992;9965-9971.