RWJ-54428 (MC-02,479), a new cephalosporin with high affinity for penicillin-binding proteins, including PBP 2a, and stability to staphylococcal beta-lactamases

Antimicrobial Agents and Chemotherapy

Volumn 47, Issue 2, 2003, Pages 658-664

  Malouin, Francois ^a,b   Blais, Johanne ^a   Chamberland, Suzanne ^a,c   Hoang, Monica ^a   Park, Craig ^a   Chan, Christin ^a   Mathias, Kristina ^a   Hakem, Samia ^a   Dupree, Kelly ^a   Liu, Eric ^a   Nguyen, Tien ^a   Dudley, Michael N ^a  

^a Essential Therapeutics Inc   (United States)

^b UNIVERSITÉ DE SHERBROOKE   (Canada)

^c Ulysses Pharmaceuticals Canada   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7 [[(2 AMINO 5 CHLORO 4 THIAZOLYL)(HYDROXYIMINO)ACETYL]AMINO] 3 [[3 [[(2 AMINOETHYL)THIO]METHYL] 4 PYRIDINYL]THIO] 8 OXO 5 THIA 1 AZABICYCLO[4.2.0]OCT 2 ENE 2 CARBOXYLIC ACID; AMPICILLIN; BETA LACTAMASE; CEFACLOR; CEFALORIDINE; CEFALOTIN; CEFAMANDOLE; CEFAZOLIN; CEFOTAXIME; CEFTAZIDIME; CEPHALOSPORIN DERIVATIVE; CILASTATIN PLUS IMIPENEM; ERYTHROMYCIN; IMIPENEM; METICILLIN; NAFCILLIN; OXACILLIN; PENICILLIN BINDING PROTEIN; PENICILLIN BINDING PROTEIN 2A; PENICILLIN G; UNCLASSIFIED DRUG; VANCOMYCIN;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATE; BINDING AFFINITY; CONTROLLED STUDY; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG STABILITY; ENTEROCOCCUS HIRAE; HYDROLYSIS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN STABILITY; STREPTOCOCCUS PNEUMONIAE;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CARRIER PROTEINS; CEPHALOSPORINS; ENTEROCOCCUS; HEXOSYLTRANSFERASES; METHICILLIN RESISTANCE; MICROBIAL SENSITIVITY TESTS; MURAMOYLPENTAPEPTIDE CARBOXYPEPTIDASE; PENICILLIN-BINDING PROTEINS; PEPTIDYL TRANSFERASES; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE;

EID: 0037311537     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.47.2.658-664.2003     Document Type: Article

References (41)

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