In vitro and in vivo antibacterial activities of OPC-20011, a novel parenteral broad-spectrum 2-oxaisocephem antibiotic

Antimicrobial Agents and Chemotherapy

Volumn 42, Issue 11, 1998, Pages 2943-2949

  Matsumoto, Makoto ^a   Tamaoka, Hisashi ^a   Ishikawa, Hiroshi ^a   Kikuchi, Mikio ^a  

^a OTSUKA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 OXAISOCEPHEM DERIVATIVE; 7 [2 (2 AMINO 4 THIAZOLYL) 2 (CYCLOPENTYLOXYIMINO)ACETAMIDO] 3 [(1 ETHOXYCARBONYLMETHYL 4 PYRIDINIO)THIOMETHYL] 2 OXAISOCEPHEM 4 CARBOXYLIC ACID; 7 [2 (2 AMINO 4 THIAZOLYL) 2 (CYCLOPENTYLOXYIMINO)ACETAMIDO] 3 [(1 ETHOXYCARBONYLMETHYL 4 PYRIDINIO)THIOMETHYL] 3 CEPHEM 4 CARBOXYLIC ACID; AMPICILLIN; ANTIBIOTIC AGENT; CARBON 14; CEFOTIAM; CEFPIROME; CEFTAZIDIME; CEPHEM DERIVATIVE; FLOMOXEF; IMIPENEM; ION; METICILLIN; PENICILLIN BINDING PROTEIN; PENICILLIN G; PLASMA PROTEIN; UNCLASSIFIED DRUG; VANCOMYCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERICIDAL ACTIVITY; BACTERIOSTASIS; BINDING AFFINITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG PROTEIN BINDING; DRUG STRUCTURE; ENTEROCOCCUS FAECALIS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MALE; MAMMAL; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NONHUMAN; PENICILLIN RESISTANCE; PRIORITY JOURNAL; RAT; RESPIRATORY TRACT INFECTION; SPECIES DIFFERENCE; STREPTOCOCCUS PNEUMONIAE; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0031724519     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.42.11.2943     Document Type: Article

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