Penicillin-binding protein 2a from methicillin-resistant Staphylococcus aureus: Kinetic characterization of its interactions with β-lactams using electrospray mass spectrometry

Biochemistry

Volumn 38, Issue 20, 1999, Pages 6537-6546

  Lu, Wei Ping ^a   Sun, Yiping ^b   Bauer, Mark D ^b   Paule, Suzanne ^a   Koenigs, Paula M ^a   Kraft, William G ^a  

^a PROCTER AND GAMBLE PHARMACEUTICALS   (United States)

^b PROCTER AND GAMBLE COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAM ANTIBIOTIC; METICILLIN; PENICILLIN BINDING PROTEIN; PEPTIDOGLYCAN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; ESCHERICHIA COLI; GENE EXPRESSION; GENE SEQUENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOLECULAR CLONING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN BINDING; STAPHYLOCOCCUS AUREUS;

ACYLATION; BACTERIAL PROTEINS; BETA-LACTAMS; CARRIER PROTEINS; CLONING, MOLECULAR; ESCHERICHIA COLI; GENES, BACTERIAL; HEXOSYLTRANSFERASES; KINETICS; MACROMOLECULAR SUBSTANCES; MASS SPECTROMETRY; MEMBRANE PROTEINS; METHICILLIN; METHICILLIN RESISTANCE; MURAMOYLPENTAPEPTIDE CARBOXYPEPTIDASE; PENICILLIN G; PENICILLIN-BINDING PROTEINS; PEPTIDYL TRANSFERASES; RECOMBINANT PROTEINS; SEQUENCE ANALYSIS; STAPHYLOCOCCUS AUREUS;

EID: 0033580616     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi990025e     Document Type: Article

References (42)

1. Waxman, D. J., and Strominger, J. L. (1983) Annu. Rev. Biochem. 52, 825-869.
2. Spratt, B. G. (1994) in Bacterial Cell Wall (Ghusyen, J.-M., and Hakenbeck, R., Eds.) pp 517-534, Elsevier Sc. B. V., Amsterdam, The Netherlands.
3. Brown, D. F. J., and Reynolds, P. E. (1980) FEBS Lett. 122, 275-278.
4. Mathews, P., and Tomasz, A. (1990) Antimicrob. Agents Chemother. 34, 1777-1779.
5. Inglis, B., Mathews, P. R., and Stewart, P. R. (1988) J. Gen. Microbiol. 134, 1465-1469.
6. Hecker, S. J., Cho, I.-S., Glinka, T. W., et al. (1998) J. Antibiot. 51, 722-734.
7. Matsuhashi, M., Song, F., Ishino, F., Wachi, M., Doi, M., Inoue, M., Ubukata, K., Yamashita, N., and Konno, M. (1986) J. Bacteriol. 167, 975-980.
8. Song, M. D., Wachi, M., Doi, M., Ishino, F., and Matsuhashi, M. (1987) FEBS Lett. 221, 167-171.
9. Ryffel, C., Tesch, W., Birch-Machin, I., Reynolds, P. E., Barberis-Maino, L., Kayser, F. H., and Berger-Bachi (1990) Gene 94, 137-138.
10. Wu, C. Y. E., Hoskins, J., Balszczak, L. C., Preston, D. A., and Skatrud, P. L. (1992) Antimicrob. Agents Chemother. 36, 533-539.
11. Frank, L. J., Wisniewski, D., Hammond, G. G., Hermes, J., Marcy, A., and Cameron, P. M. (1995) Protein Expression Purif. 6, 671-678.
12. Toney, J., Hammond, G. G., Leiting, B., Pryor, K., Wu, J. K., Cuca, G. C., and Pompliano, D. L. (1998) Anal. Biochem. 255, 113-119.
13. Sun, Y., Bauer, M. D., and Lu, W.-P. (1998) J. Mass Spectrosc. 33, 1009-1016.
14. Frère, J. M., Ghuysen, J.-M., and Iwatsubo, M. (1975) Eur. J. Biochem. 57, 343-351.
15. Jamin, M., Damblon, C., Millier, S., Hakenbeck, R., and Frère, J. M. (1993) Biochem. J. 292, 735-741.
16. Roychoudhury, S., Dotzlaf, J. E., Ghag, S., and Yeh, W.-K. (1994) J. Biol. Chem. 269, 12067-12073.
17. Graves-Woodward, K., and Pratt, R. F. (1998) Biochem. J. 332, 755-761.
18. Unal, S., Hoskins, J., Flokowitsch, J. E., Wu, C. Y. E., Preston, D. A., and Skatrud, P. L. (1992) Antimicrob. Agents Chemother. 30, 1685-1691.
19. Johnson, K. A. (1986) Methods Enzymol. 134, 677-705.
20. Ghuysen, J.-M., Frère, J. M., Leyh-Bouille, Nguyen-Distèche, M., and Coyette, J. (1986) Biochem. J. 235, 159-165.
21. Frère, J. M., Nguyen-Disteche, M., Coyette, J., and Joris, B. (1992) in The Chemistry of beta-Lactams (Page, M. I., Ed.) pp 148-195, Champman and Hall, Glasgow, Scotland.
22. Zerner, B., and Bender, M. L. (1964) J. Am. Chem. Soc. 86, 3669-3674.
23. Kitz, R., and Wilson, I. (1962) J. Biol. Chem. 237, 3245-3249.
24. Strickland, S., Palmer, G., and Massey, V. (1975) J. Biol. Chem. 250, 4048-4052.
25. Zechel, D. L., Konermann, L., Withers, S. G., and Douglas, D. J. (1998) Biochemistry 37, 7664-7669.
26. Ubukata, K., Yamashita, N., and Konno, M. (1985) Antimicrob. Agents Chemother. 27, 851-857.
27. Chambers, H. F., and Sachdeva, M. (1989) J. Infect. Dis. 161, 1170-1176.
28. Roychoudhury, S., Kaiser, R. E., Brems, D. N., and Yeh, W.-K. (1996) Antimicrob. Agents Chemother. 40, 2075-2079.
29. Frère, J. M., and Joris, B. (1985) CRC Crit. Rev. Microbiol. 1, 299-396.
30. Sumita, Y., Fukasawa, M., Mitsuhashi, S., and Inoue, M. (1995) J. Antimicrob. Chemother. 35, 473-481.
31. Woodward, R. A., and Hans Bickel, B. (1981) U.S. Patent 4256739.
32. Knight, W. B., Swiderek, K. M., Sakuma, T., Calaycay, J., Shively, J. E., Lee, T. D., Covey, T. R., Shushan, B., Gree, B. G., Shah, S., Mumford, R., Dickinson, T. A., and Griffin, P. R. (1993) Biochemistry 32, 2031-2035.
33. Aplin, R. T., Robinson, C. V., Schofield, C. J., and Waley, S. G. (1993) J. Chem. Soc., Chem. Commun. 6, 121-123.
34. Saves, I., Burlet-Schiltz, O., Maveyraudd, L., Samama, J.-P., Prome, J.-C., and Masson, J.-M. (1995) Biochemistry 34, 11660-11667.
35. Brown, R. P A., Aplin, R. T., and Schofield, C. J. (1996) Biochemistry 35, 12421-12432.
36. Himoe, A., Brandt, K. G., DeSa, R. J., and Hess, G. P. (1969) J. Biol. Chem. 244, 3483-3493.
37. Coyette, J., Nguyen-Disteche, M., Lamotte-Brasseur, J., Joris, B., Fonze, E., and Frère, J.-M. (1994) Adv. Comp. Environ. Physiol. 20, 233-267.
38. Chambers, H. F., Sachdeva, M. J., and Hackbarth, C. J. (1994) Biochem. J. 301, 139-144.
39. Brocklehurst, K. (1979) Biochem. J. 181, 775-778.
40. Fresht, A. (1984) Enzyme Structure and mechanism, 2nd ed., Freeman and Co. New York.
41. Johnson, K. A. (1992) in The Enzymes, 4th ed. (Boyer, P. D., Ed.) Vol. 20, pp 1-61, Acamdemic Press, New York.).
42. Doyle, F. P., Long, A. A. W., Nayler, J. J. C., and Stove, E. R. (1961) Nature 192, 1183-1184.