Insulin sensitivity and hemodynamic responses to insulin in Wistar- Kyoto and spontaneously hypertensive rats

American Journal of Physiology - Endocrinology and Metabolism

Volumn 271, Issue 4 34-4, 1996, Pages

  Pître, Maryse ^a   Nadeau, André ^a   Bachelard, Hélène ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

blood flow; glucose clamp; hypertension

Indexed keywords

GLUCOSE; INSULIN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; GLUCOSE CLAMP TECHNIQUE; HEMODYNAMICS; HYPERTENSION; INSULIN SENSITIVITY; MALE; MESENTERY BLOOD FLOW; NONHUMAN; PRIORITY JOURNAL; RAT; SPONTANEOUSLY HYPERTENSIVE RAT;

EID: 0029909740     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.1996.271.4.e658     Document Type: Article

References (39)

1. Anderson, E. A., R. P. Hoffman, T. W. Balon, C. A. Sinkey, and A. L. Mark. Hyperinsulinemia produces both sympathetic neural activation and vasodilatation in normal humans. J. Clin. Invest. 87. 2246-2252, 1991.
2. Baron, A. D., G. Brechtel-Hook, A. Johnson, and D. Hardin. Skeletal muscle blood flow. A possible link between insulin resistance and blood pressure. Hypertension Dallas 21: 129-135, 1993.
3. Baron, A. D., H. O. Steinberg, H. Chaker, R. Leaming, A. Johnson, and G. Brechtel. Insulin-mediated skeletal muscle vasodilation contributes to both insulin sensitivity and responsiveness in lean humans. J. Clin. Invest. 96: 786-792, 1995.
4. Berne, C., J. Fagius, L. Pollare, and P. Hjemdahl. The sympathetic response to euglycemic hyperinsulinaemia: evidence from microelectrode nerve recordings in healthy subjects. Diabetologia 35: 873-879, 1992.
5. Bonora, E., I. Zavaroni, O. Alpi, A. Pezzarossa, F. Brushi, E. Dall Aglio, L. Guerra, C. Coscelli, and U. Butturini. Relationship between blood pressure and plasma insulin in nonobese and obese non-diabetic subjects. Diabetologia 30: 719-723, 1987.
6. Brands, M. W., D. A. Hildebrandt, H. I. Mizelle, and J. E. Hall. Sustained hyperinsulinemia increases arterial pressure in conscious rats. Am. J. Physiol. 260 (Regulatory Integrative Comp. Physiol. 29): R764-R768, 1991.
7. Buchanan, T. A., G. F. Sipos, N. Madrilejo, C. Liu, and V. Campese. Hypertension without peripheral insulin resistance in spontaneously hypertensive rats. Am. J. Physiol. 262 (Endocrinol. Metab. 25): E14-E19, 1992.
8. DeFronzo, R. A., and E. Ferrannini. Insulin resistance: a multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care 14: 173-194, 1991.
9. DeFronzo, R. A., J. D. Tobin, and R. Andres. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am. J. Physiol. 237 (Endocrinol. Metab. Gastrointest. Physiol. 6): E214-E223, 1979.
10. Desbuquois, B., and G. D. Aurbach. Use of polyethylene glycol to separate free and antibody-bound peptide hormones in radioimmunoassays. J. Clin. Endocrinol. 33: 732-738, 1971.
11. Ferrannini, E. Insulin and blood pressure: possible role of hemodynamics. Clin. Exp. Hypertens. 14: 271-284, 1992.
12. Ferrannini, E., E. Buzzigoli, R. Bonadonna, M. A. Giorico, M. Oleggini, L. Graziadel, R. Pedrinelli, L. Brandi, and S. Bevilacqua. Insulin resistance in essential hypertension. N. Engl. J. Med. 317: 350-357, 1987.
13. Frontoni, S., L. Ohman, J. R. Haywood, R. A. DeFronzo, and L. Rossetti. In vivo insulin action in genetic models of hypertension. Am. J. Physiol. 262 (Endocrinol. Metab. 25): E191-E196, 1992.
14. Greene, A. D., P. J. Tonellato, J. Lui, J. H. Lombard, and A. W. Cowley. Microvascular rarefaction and tissue vascular resistance in hypertension. Am J. Physiol. 256 (Heart Circ. Physiol. 25): H126-H131, 1989.
15. Hall, J. E., M. W. Brands, S. D. Kivlighn, H. L. Mizelle, D. A. Hildebrandt, and C. A. Gaillard. Chronic hyperinsulinemia and blood pressure: interaction with catecholamines? Hypertension Dallas 15: 519-527, 1990.
16. Hall, J. E., T. G. Coleman, and H. L. Mizelle. Arterial pressure and renal function during chronic hyperinsulinemia (Abstract). Kidney Int. 35: 326, 1989.
17. Haywood, J. R., R. A. Shaffer, C. Fastenow, G. D. Fink, and M. J. Brody. Regional blood flow measurement with pulsed Doppler flowmeter in conscious rat. Am. J. Physiol. 241 (Heart Circ. Physiol. 10): H273-H278, 1981.
18. Hwang, I. S., H. Ho, B. B. Hoffman, and G. M. Reaven. Fructose-induced insulin resistance and hypertension in rats. Hypertension Dallas 10: 512-516, 1987.
19. James, D. E., K. M. Burleigh, L. H. Storlien, S. P. Bennett, and E. W. Kraegen. Heterogeneity of insulin action in muscle: influence of blood flow. Am. J. Physiol. 251 (Endocrinol. Metab. 14): E422-E430, 1986.
20. James, D. E., and R. C. Piper. Insulin resistance, diabetes, and the insulin-regulated trafficking of Glut-4. J. Cell Biol. 126: 1123-1126, 1994.
21. Julius, S., T. Gudbrandsson, K. Jamerson, S. T. Shahab, and O. Andersson. The hemodynamic link between insulin resistance and hypertension. J. Hypertens. 9: 983-986, 1991.
22. Kahn, B. B. Facilitative glucose transporters: regulatory mechanisms and dysregulation in diabetes. J. Clin. Invest. 89: 1367-1374, 1989.
23. Kahn, C. R., and M. J. Saad. Alterations in insulin receptor and substrate phosphorylation in hypertensive rats. Am. J. Soc. Nephrol. 3: S69-S77, 1992.
24. Konishi, M., and C. Su. Role of endothelium in dilator responses of spontaneously hypertensive rat arteries. Hypertension Dallas 5: 881-886, 1983.
25. Kvetnansky, R., R. McCarty, N. B. Thoa, C. R. Lake, and I. J. Kopin. Sympatho-adrenal responses of spontaneously hypertensive rats to immobilization stress. Am. J. Physiol. 236 (Heart Circ. Physiol. 5): H457-H462, 1979.
26. Laakso, M., S. Edelman, G. Brechtel, and A. D. Baron. Impaired insulin mediated skeletal muscle blood flow in patients with NIDDM. Diabetes 41: 1076-1083, 1992.
27. Laakso, M., S. V. Edelman, G. Brechtel, and A. D. Baron. Decreased effect of insulin to stimulate skeletal muscle blood flow in obese man. J. Clin. Invest. 85: 1844-1852, 1990.
28. Lembo, G., R. Napoli, B. Capaldo, V. Rendina, G. Iaccarino, M. Volpe, B. Trimarco, and L. Saccà. Abnormal sympathetic overactivity evoked by insulin in the skeletal muscle of patients with essential hypertension. J. Clin. Invest. 90: 24-29, 1992.
29. Liang, C. S., J. U. Doherty, R. Faillace, K. Maekawa, S. Arnold, H. Gavras, and W. B. Hood. Insulin infusion in conscious dogs: effects on systemic and coronary hemodynamics, regional blood flows, and plasma catecholamines. J. Clin. Invest. 69: 1321-1336, 1982.
30. Morgan, D. A., T. W. Balon, and A. Mark. Hyperinsulinemia produces exaggerated increases in sympathoadrenal activity in spontaneously hypertensive rats (Abstract). Hypertension Dallas 16: 339, 1990.
31. Prewitt, R. L., I. H. Chen, and R. Dowell. Development of microvascular rarefaction in the spontaneously hypertensive rat. Am. J. Physiol. 243 (Heart Circ. Physiol. 12): H243-H251, 1982.
32. Rao, R. H. Insulin resistance in spontaneously hypertensive rats. Difference in interpretation based on insulin infusion rate or on plasma insulin in glucose clamp studies. Diabetes 42: 1364-1371, 1993.
33. Reaven, G. M., and H. Chang. Relationship between blood pressure, plasma insulin and triglyceride concentration, and insulin action in spontaneous hypertensive and Wistar Kyoto rats. Am. J. Hypertens. 4: 34-38, 1991.
34. Reaven, G. M., and H. Ho. Sugar-induced hypertension in Sprague-Dawley rats. Am. J. Hypertens. 4: 610-614, 1991.
35. Richterich, R., and H. Dauwalder. Zur bertimmung der plasmaglucokonzentration mit der hexokinase-glucose-6-phosphat-dehydrogenase methode. Schweiz Med. Wochenschr. 101: 615-618, 1971.
36. Rocchini, A. P. Insulin resistance and blood pressure regulation in obese and non-obese subjects. Hypertension Dallas 17: 837-842, 1991.
37. Schultz, T. A., S. B. Lewis, D. K. Wesbie, and J. D. Wallin. Glucose delivery: a modulator of glucose uptake in contracting skeletal muscle. Am J. Physiol. 233 (Endocrinol. Metab. Gastrointest. Physiol. 2): E514-E518, 1977.
38. Swislocki, A., and A. Tsuzuki. Insulin resistance and hypertension: glucose intolerance, hyperinsulinemia, and elevated free fatty acids in the lean spontaneously hypertensive rat. Am. J. Med. Sci. 306: 282-286, 1993.
39. Wright, C. E., J. A. Angus, and P. I. Korner. Vascular amplifier properties in renovascular hypertension in conscious rabbits. Hindquarters responses to constrictor and dilator stimuli. Hypertension Dallas 9: 122-131, 1987.