SCOPUS 정보 검색 플랫폼

Volumn 57, Issue 39, 2001, Pages 8357-8367

Research on anti-HIV-1 agents. Part 2: Solid-phase synthesis, biological evaluation and molecular modeling studies of 2,5,6-trisubstituted-4(3H)-pyrimidinones targeting HIV-1 reverse transcriptase

(6) Botta, Maurizio a Corelli, Federico a Maga, Giovanni b Manetti, Fabrizio a Renzulli, Michela a Spadari, Silvio b

a UNIVERSITY OF SIENA (Italy)

b CNR (Italy)

Author keywords

Anti HIV 1 agents; Molecular docking; Pyrimidinones; Solid phase synthesis

Indexed keywords

2 [1' (4' AMINO)BUTYL]AMINO 6 BENZYL 4(3H) PYRIMIDINONE; 2 [1' (4' AMINO)BUTYL]AMINO 6 BENZYL 5 METHYL 4(3H) PYRIMIDINONE; 2 [1' (4' HYDROXY)BUTYL]AMINO 3 METHYL 4(3H) PYRIMIDINONE; 2 [1' (4' HYDROXY)BUTYL]THIO 6 BENZYL 4(3H) PYRIMIDINONE; 2 [1' (4' HYDROXY)BUTYL]THIO 6 BENZYL 5 METHYL 4(3H) PYRIMIDINONE; 2 [1' (4' HYDROXY)BUTYL]THIO 6 METHYL 4(3H) PYRIMIDINONE; 4(3H) PYRIMIDINONE DERIVATIVE; 6 BENZYL 2 [1' (4' HYDROXY)BUTYL]AMINO 4(3H) PYRIMIDINONE; ANTIVIRUS AGENT; NEVIRAPINE; PYRIMIDINONE DERIVATIVE; RNA DIRECTED DNA POLYMERASE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CHEMICAL BINDING; CHEMICAL REACTION; DRUG INHIBITION; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; EVALUATION; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VITRO STUDY; MEDICAL RESEARCH; MOLECULAR MODEL; MUTATION; PRIORITY JOURNAL; REACTION ANALYSIS; SOLID PHASE EXTRACTION;

EID: 0035944152 PISSN: 00404020 EISSN: None Source Type: Journal
DOI: 10.1016/S0040-4020(01)00815-8 Document Type: Article

Times cited : (44)

References (43)

1
- 0034007915
- (2000) J. Comput-Aided Mol. Des. , vol.14 , pp. 355-368
- Manetti, F.¹ Corelli, F.² Mongelli, N.³ Lombardi Borgia, A.⁴ Botta, M.⁵

2
- 0033683359
- (2000) Chem. Rev. , vol.100 , pp. 2091-2157
- Guillier, F.¹ Orain, D.² Bradley, M.³

3
- 0003861336
- Elsevier: Oxford
- (1998) Solid-Supported Combinatorial and Parallel Synthesis of Small-Molecular-Weight Compound Libraries; Tetrahedron Organic Chemistry Series , vol.17
- Obrecht, D.¹ Villalgordo, J.M.²

4
- 0000409291
- Taylor, E. C., Weissberger, A., Eds.; Wiley: New York
- (1994) The Chemistry of Heterocyclic Compounds , vol.52 , pp. 371-377
- Brown, D.J.¹

5
- 0032910094
- and references cited therein
- (1999) J. Heterocycl. Chem. , vol.36 , pp. 97-104
- Vedernikova, I.V.¹ Haemers, A.² Ryabukhin, Y.I.³

6
- 0031040133
- (1997) Helv. Chim. Acta , vol.80 , pp. 65-72
- Obrecht, D.¹ Abrecht, C.² Grieder, A.³ Villalgordo, J.M.⁴

7
- 0032874389
- (1999) Bioorg. Med. Chem. , vol.7 , pp. 1925-1931
- Botta, M.¹ Occhionero, F.² Nicoletti, R.³ Mastromarino, R.⁴ Conti, C.⁵ Magrini, M.⁶ Saladino, R.⁷

8
- 0030759473
- (1997) J. Med. Chem. , vol.40 , pp. 2363-2373
- Kim, D.K.¹ Gam, J.² Kim, Y.W.³ Lim, J.⁴ Kim, H.T.⁵ Kim, K.H.⁶

9
- 0030994577
- (1997) J. Med. Chem. , vol.40 , pp. 1845-1854
- Pontikis, R.¹ Benhida, R.² Aubertin, A.M.³ Grierson, D.S.⁴ Monneret, C.⁵

10
- 0027381149
- (1993) Mol. Pharmacol. , vol.44 , pp. 694-701
- Balzarini, J.¹ Karlsson, A.² De Clercq, E.³

11
- 0029016023
- (1995) Nucleosides Nucleotides , vol.14 , pp. 575-584
- Baba, M.¹ Tanaka, H.² Miyasaka, T.³ Yuasa, S.⁴ Ubasawa, M.⁵ Walker, R.T.⁶ De Clercq, E.⁷

12
- 0033602141
- (1999) J. Med. Chem. , vol.42 , pp. 619-627
- Mai, A.¹ Artico, M.² Sbardella, G.³ Massa, S.⁴ Novellino, E.⁵ Greco, G.⁶ Loi, A.G.⁷ Tramontano, E.⁸ Marongiu, M.E.⁹ La Colla, P.¹⁰

13
- 15444340492
- (1997) J. Med. Chem. , vol.40 , pp. 1447-1454
- Mai, A.¹ Artico, M.² Sbardella, G.³ Quartarone, S.⁴ Massa, S.⁵ Loi, A.G.⁶ De Montis, A.⁷ Scintu, F.⁸ Putzolu, M.⁹ La Colla, P.¹⁰

14
- 0034085298
- (2000) Synthesis , pp. 479-495
- Pedersen, O.S.¹ Pedersen, E.B.²

15
- 0032737069
- (1999) Antiviral Chem. Chemother. , vol.10 , pp. 285-314
- Pedersen, O.S.¹ Pedersen, E.B.²

16
- 0032368082
- (1998) Collect. Czech. Chem. Commun. , vol.63 , pp. 449-479
- De Clercq, E.¹

17
- 0029951587
- (1996) Il Farmaco , vol.51 , pp. 305-331
- Artico, M.¹

18
- 0003677751
- Ref. 1

19
- 0003502490
- (1997) Med. Chem. Res. , vol.7 , pp. 546-556
- Krikorian, D.¹ Parushev, S.² Tarpanov, V.³ Mechkarova, P.⁴ Mikhova, B.⁵ Botta, M.⁶ Corelli, F.⁷ Maga, G.⁸ Spadari, S.⁹

20
- 0028017355
- (1994) Nucleosides Nucleotides , vol.8 , pp. 1769-1777
- Botta, M.¹ Saladino, R.² Anzini, M.³ Corelli, F.⁴

21
- 0032516263
- (1998) Tetrahedron Lett. , vol.39 , pp. 3307-3310
- Nizi, E.¹ Botta, M.² Corelli, F.³ Manetti, F.⁴ Messina, F.⁵ Maga, G.⁶

22
- 0002826249
- (1995) Trends Org. Chem. , vol.5 , pp. 57-81
- Botta, M.¹ Saladino, R.² Occhionero, F.³ Nicoletti, R.⁴

23
- 0030690018
- (1997) Tetrahedron Lett. , vol.38 , pp. 8249-8252
- Botta, M.¹ Occhionero, F.² Saladino, R.³ Crestini, C.⁴ Nicoletti, R.⁵

24
- 0004531358
- (1965) Polymer Lett. (Part B) , vol.3 , pp. 505-508
- Aryes, J.T.¹ Mann, C.K.²

25
- 0027363643
- (1993) J. Med. Chem. , vol.36 , pp. 2956-2963
- Delle Monache, G.¹ Botta, B.² Delle Monache, F.³ Espinal, R.⁴ De Bonnevaux, S.C.⁵ De Luca, C.⁶ Botta, M.⁷ Corelli, F.⁸ Carmignani, M.⁹

26
- 0003602589
- note

27
- 0000482191
- (1989) J. Am. Chem. Soc. , vol.111 , pp. 3973-3976
- Arnold, L.D.¹ Vederas, J.C.²

28
- 0003677753
- note

29
- 0033571714
- (1999) Bioorg. Med. Chem. Lett. , vol.9 , pp. 3249-3254
- Delle Monache, G.¹ Volpe, A.R.² Delle Monache, F.³ Vitali, A.⁴ Botta, B.⁵ Espinal, R.⁶ De Bonnevaux, S.C.⁷ De Luca, C.⁸ Botta, M.⁹ Corelli, F.¹⁰ Carmignani, F.¹¹

30
- 0001467837
- (1984) Tetrahedron , vol.17 , pp. 3313-3320
- Botta, M.¹ Cavalieri, M.² Ceci, D.³ De Angelis, F.⁴ Finizia, G.⁵ Nicoletti, R.⁶

31
- 0026691450
- (1992) Eur. J. Med. Chem., Chim. Thér. , vol.27 , pp. 251-257
- Botta, M.¹ Artico, M.² Massa, S.³ Gambacorta, A.⁴ Marongiu, M.E.⁵ Pani, A.⁶ La Colla, P.⁷

32
- 0027521797
- (1993) Antivir. Chem. Chemother. , vol.4 , pp. 361-368
- Artico, M.¹ Massa, S.² Mai, A.³ Marongiu, M.E.⁴ Piras, G.⁵ Tramontano, E.⁶ La Colla, P.⁷

33
- 0029976422
- (1996) J. Med. Chem. , vol.39 , pp. 1589-1600
- Hopkins, A.L.¹ Ren, J.² Esnouf, R.M.³ Willcox, B.E.⁴ Jones, E.Y.⁵ Ross, C.⁶ Miyasaka, T.⁷ Walker, R.T.⁸ Tanaka, H.⁹ Stammers, D.K.¹⁰ Stuart, D.I.¹¹

34
- 0029095334
- (1995) J. Med. Chem. , vol.38 , pp. 3258-3263
- Mai, A.¹ Artico, M.² Sbardella, G.³ Massa, S.⁴ Loi, A.G.⁵ Tramontano, E.⁶ Scano, P.⁷ La Colla, P.⁸

35
- 0029977510
- (1996) Drug Des. Discov. , vol.13 , pp. 29-47
- Arnold, E.¹ Das, K.² Ding, J.³ Yadav, P.N.S.⁴ Hsiou, Y.⁵ Boyer, P.L.⁶ Hughes, S.H.⁷

36
- 0028947588
- (1995) Nature Struct. Biol. , vol.2 , pp. 293-302
- Ren, J.¹ Esnouf, R.² Garman, E.³ Somers, D.⁴ Ross, C.⁵ Kirby, I.⁶ Keeling, J.⁷ Darby, G.⁸ Jones, Y.⁹ Stuart, D.¹⁰ Stammers, D.¹¹

37
- 13144282707
- (1998) J. Mol. Biol. , vol.284 , pp. 313-323
- Hsiou, Y.¹ Das, K.² Ding, J.³ Clark A.D., Jr.⁴ Kleim, J.P.⁵ Rosner, M.⁶ Winkler, I.⁷ Riess, G.⁸ Hughes, S.H.⁹ Arnold, E.¹⁰

38
- 0000299809
- (1990) J. Am. Chem. Soc. , vol.112 , pp. 4768-4774
- Jorgensen, W.L.¹ Severance, D.L.²

39
- 0028924567
- (1995) Nature Struct. Biol. , vol.2 , pp. 303-308
- Esnouf, R.¹ Ren, J.² Ross, C.³ Jones, Y.⁴ Stammers, D.⁵ Stuart, D.⁶

40
- 0029645409
- (1995) Structure , vol.3 , pp. 915-926
- Ren, J.¹ Esnouf, R.² Hopkins, A.³ Ross, C.⁴ Jones, Y.⁵ Stammers, D.⁶ Stuart, D.⁷

41
- 84986437005
- (1990) J. Comput. Chem. , vol.11 , pp. 440-458
- Mohamadi, F.¹ Richards, N.G.J.² Guida, W.C.³ Liskamp, R.⁴ Lipton, M.⁵ Caufield, C.⁶ Chang, G.⁷ Hendrickson, T.⁸ Still, W.C.⁹

42
- 0021757436
- (1984) J. Am. Chem. Soc. , vol.106 , pp. 765-784
- Weiner, S.J.¹ Kollman, P.A.² Case, D.A.³ Singh, U.C.⁴ Ghio, C.⁵ Alagona, G.⁶ Profeta, S.⁷ Weiner, P.⁸

43
- 84988053694
- (1986) J. Comput. Chem. , vol.7 , pp. 230-252
- Weiner, S.J.¹ Kollman, P.A.² Nguyen, D.T.³ Case, D.A.⁴

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.