Synthesis, biological evaluation, and pharmacophore generation of uracil, 4(3H)-pyrimidinone, and uridine derivatives as potent and selective inhibitors of parainfluenza 1 (Sendai) virus

Journal of Medicinal Chemistry

Volumn 44, Issue 26, 2001, Pages 4554-4562

  Saladino, R ^a   Crestini, C ^a   Palamara, A T ^b,c   Danti, M C ^d   Manetti, F ^d   Corelli, F ^d   Garaci, E ^c   Botta, M ^d  

^a UNIVERSITY OF TUSCIA   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

^d UNIVERSITY OF SIENA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

1,3 DIMETHYL 6 CHLOROMETHYLURACIL; 1,3,6 TRIMETHYLURACIL; 6 METHYL 4(3H) PYRIMIDINONE DERIVATIVE; 6 OXIRANYLMETHYLURACIL DERIVATIVE; 6 OXIRANYLURACIL DERVATIVE; ANTIVIRUS AGENT; PYRIMIDINONE DERIVATIVE; UNCLASSIFIED DRUG; URACIL DERIVATIVE; URIDINE DERIVATIVE;

ALKYLATION; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; MOLECULAR MODEL; NONHUMAN; PARAINFLUENZA VIRUS; STRUCTURE ACTIVITY RELATION; VIRUS REPLICATION;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; DOGS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PYRIMIDINONES; SENDAI VIRUS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; URACIL; URIDINE;

EID: 0035924181     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm010938i     Document Type: Article

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