Inhibition of TIMP1 enhances angiogenesis in vivo and cell migration in vitro

Microvascular Research

Volumn 65, Issue 1, 2003, Pages 9-17

  Reed, May J ^a   Koike, Teruhiko ^a   Sadoun, Eman ^a   Sage, E Helene ^b   Puolakkainen, Pauli ^b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b HOPE HEART INSTITUTE   (United States)

Author keywords

Angiogenesis; Collagen I; Endothelial cells; Invasion; Matrix metalloproteinases; Mice; Microvascular; Migration; Tissue inhibitor of metalloproteinase

Indexed keywords

COLLAGEN TYPE 1; COLLAGENASE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 1329; POLYVINYL ALCOHOL; PROTEIN ANTIBODY; TISSUE INHIBITOR OF METALLOPROTEINASE 1; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ELONGATION; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; CELL ULTRASTRUCTURE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME INHIBITION; GROWTH INHIBITION; HUMAN; IMPLANT; MALE; MICROVASCULATURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN CELL; SKIN FIBROBLAST; VASCULARIZATION;

POTATO VIRUS A;

EID: 0037288473     PISSN: 00262862     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0026-2862(02)00026-2     Document Type: Article

References (39)

1. Alonso D.F., Skilton G., De lorenzo M.S., Scursoni A.M., Yoshiji H., Gomez D.E. Histopathological findings in a highly invasive mouse mammary carcinoma transfected with human tissue inhibitor of metalloproteinases-1. Oncol Rep. 5:1998;1083-1087.
2. Bodden M.K., Harber G.J., Birkedal-Hansen B., Windsor L.J., Caterina N.C.M., Engler J.A., Birkedal-Hansen H. Functional domains of human TIMP-1 (tissue inhibitor of metalloproteinase). J. Biol. Chem. 269:1994;18943-18952.
3. Brew K., Dinakarpandian D., Nagase H. Tissue inhibitors of metalloproteinases Evolution, structure, and function . Biochim. Biophys. Acta. 1477:2000;267-283.
4. Chesler L., Golde D.W., Bersch N., Johnson M. Metalloproteinase inhibition and erythroid potentiation are independent activities of tissue inhibitor of metalloproteinases-1. Blood. 8612:1995;4506-4515.
5. Clark E.A., King W.G., Brugge F.S., Symons M., Hynes R.O. Integrin-mediated signals regulated by members of the rho family of GTPases. J. Cell. Biol. 142:1998;573-586.
6. Cornelius L., Nehring L., Roby J., Parks W., Welgus H. Human dermal microvascular endothelial cells produce matrix metalloproteinases in response to angiogenic factors and migration. J. Invest. Dermatol. 105:1995;170-176.
7. Davidson J.M., Klagsbrun M., Hill K.E., Buckley A., Sullivan R., Brewer P., Woodward S.C. Accelerated wound repair, cell proliferation, and collagen accumulation are produced by a cartilage-derived growth factor. J. Cell Biol. 100:1985;1219-1227.
8. Deryugina E.I., Bourdon M.A., Luo G., Reisfeld R.A., Strongin A. Matrix metalloproteinase-2 activation modulates glioma cell migration. Cell. 110:1997;2473-2482.
9. Ellerbroek S.M., Wu Y.I., Overall C.M., Stack M.S. Functional interplay between Type I collagen and cell surface matrix metalloprotease activity. J. Biol. Chem. 276:(27):2001;24833-24842.
10. Fajardo L.F., Kowalski J., Dwan H., Prionas S.D., Allison A.C. The disc angiogenesis system. Lab. Invest. 587:1988;718-724.
11. Fisher C., Gilbertson-Beadling S., Powers E. Interstitial collagenase is required for angiogenesis in vitro. Dev. Biol. 162:1994;499-510.
12. Gálvez B.G., Salomón M.R., Albar J.P., Sánchez-Madrid F., Arroyo A.G. Membrane type 1-matrix metalloproteinase is activated during migration of human endothelial cells and modulates endothelial motility and matrix remodeling. J. Biol. Chem. 276:2001;37491-37500.
13. Giannelli G., Falk-Marzillier J., Schiraldi O., Stetler-Stevenson W.G., Quaranta V. Induction of cell migration by matrix metalloprotease-2 cleavage of Laminin-5. Science. 277:1997;225-228.
14. Guedez L., McMarlin A.J., Kingma D.W., Bennett T.A., Stetler-Stevenson M., Stetler-Stevenson W.G. Tissue inhibitor of metalloproteinase-1 alters the tumorigenicity of Burkitt's lymphoma via divergent effects on tumor growth and angiogenesis. Am. J. Pathol. 1584:2001;1207-1215.
15. Hanemaaijar R., Koolwijk P., Clercq L., de Vree W., van Hinsbergh V. Regulation of matrix metalloproteinase expression in human vein and microvascular endothelial cells. Biochem. J. 296:1993;803-809.
16. Hayakawa T. Tissue inhibitors of metalloproteinases and their cell growth-promoting activity. Cell Struct. Funct. 3:1994;109-114.
17. Henriet P., Rousseau G.G., Eeckhout Y. Cloning and sequencing of mouse collagenase cDNA. FEBS Lett. 11598. 310:1992;175-178.
18. Henriet P., Blavier L., Declerck Y.A. Tissue inhibitors of metalloproteinases (TIMP) in invasion and proliferation. AM-PIS. 107:1999;111-119.
19. Horwitz A.R., Parsons J.T. Cell migration - Movin' on. Science. 286:1999;1102-1103.
20. Jackson C., Nguyen M. Human microvascular endothelial cells differ from macrovascular endothelial cells in their expression of matrix metalloproteinases. Int. J. Biochem. Cell Biol. 29:1997;1167-1177.
21. Johnson M., Kim H., Chesler L., Tsao-wu G., Bouck N., Polverini P. Inhibition of angiogenesis by tissue inhibitor of metalloproteinase. J. Cell Physiol. 160:1994;194-202.
22. Knauper V., Lopez-Otin C., Smith B., Knight G., Murphy G. Biochemical characterization of human collagenase-3. J. Biol. Chem. 271:1996;1544-1550.
23. Mitchell P.G., Magna H.A., Reeves L.M., Lopresti-Morrow L.L., Yocum S.A., Rosner P.J., Geoghegan K.F., Hambor J.E. Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage. J. Clin. Invest. 97:1996;3761-3768.
24. Nagase H., Woessner J.F. Matrix metalloproteinases. Biol. Chem. 274:1999;21491-21494.
25. Nakahara H., Mueller S.C., Nomizu M., Yamada Y., Yeh Y., Chen W.T. Activation of betal integrin signaling stimulates tyrosine phosphorylation of p190(RhoGAP) and membrane-protrusive activities at invadopodia. J. Biol. Chem. 273:1998;9-12.
26. Pilcher B., Dumin J., Dudbeck B., Krane S., Welgus H., Parks W. The activity of collagenase-1 is required for keratinocyte migration on a type I collagen matrix. J. Cell Biol. 137:1997;1445-1457.
27. Pilcher B., Wang M., Qin X.J., Parks W.C., Senior R.M., Welgus H.G. Role of matrix metalloproteinases and their inhibition in cutaneous wound healing and allergic contact hypersensitivity. Ann. N.Y. Acad. Sci. 878:1999;12-24.
28. Planus E., Galiacy S., Matthay M., Laurent V., Gavrilovic J., Murphy G., Clerici C., Isabey D., Lafuma C., d'Ortho M.P. Role of collagenase in mediating in vitro alveolar epithelial wound repair. J. Cell Sci. 112:1999;243-252.
29. Ravanti L., Heino J., López-Otín C., Kähäri V. Induction of collagenase-3 (MMP-13) expression in human skin fibroblasts by three-dimensional collagen is mediated by p38 mitogen-activated protein kinase. J. Biol. Chem. 274:1999;2446-2455.
30. Reed M., Corsa A., Pendergrass W., Penn P., Sage E., Abrass I. Neovascularization in aged mice delayed angiogenesis is coincident with decreased levels of transforming growth factor betal and type I collagen . Am. J. Pathol. 152:1998;113-123.
31. Reed M.J., Corsa A., Kudravi S., McCormick R., Arthur W.T. A deficit in collagenase activity contributes to impaired migration of aged microvascular endothelial cells. J. Cell Biochem. 77:(1):2000;116-126.
32. Saarialho-Kere U., Kovacs S., Pentland A., Olerud J., Welgus H., Parks W. Cell-matrix interactions modulate interstitial collagenase expression by human keratinocytes actively involved in wound healing. J. Clin. Invest. 92:1993;2858-2866.
33. Singer A.J., Clark R.A. Mechanisms of disease cutaneous wound healing . N. Engl. J. Med. 341:1999;738-746.
34. Smilenov L.B., Mikhailov A., Pelham R.J., Marcantonio E.E., Gundersen G.G. Focal adhesion motility revealed in stationary fibroblasts. Science. 286:1999;1172-1174.
35. Stetler-Stevenson W.G., Yu A. Proteases in invasion matrix metalloproteinases . Semin. Cancer Biol. 11:2001;143-152.
36. Taylor K.B., Windsor L.J., Caterina N.C.M., Bodden M.K. The mechanism of inhibition of collagenase by TIMP-1. J. Biol. Chem. 271:1996;23938-23945.
37. Thorgeirsson U.P., Yoshiji H., Sinha C.C., Gomez D.E. Breast cancer, tumor neovasculature and the effect of tissue inhibitor of metalloproteinases-1 (TIMP-1) on angiogenesis. In Vivo. 10:1996;137-144.
38. Uría J.A., Jimenéz M.G., Balbín M., Freije J.M.P., López-Otin C. Differential effects of transforming growth factor-beta on the expression of collagenase-1 and collagenase-3 in human fibroblasts. J. Biol. Chem. 273:1998;9769-9777.
39. Vallon R., Muller R., Moosmayer D., Gerlack E., Angel P. The catalytic domain of activated collagenase I (MMP-1) is absolutely required for interaction with its specific inhibitor, tissue inhibitor of metalloproteinases-1 (TIMP-1). Eur. J. Biochem. 244:1997;81-88.