The catalytic domain of activated collagenase I (MMP-1) is absolutely required for interaction with its specific inhibitor, tissue inhibitor of metalloproteinases-1 (TIMP-1)

European Journal of Biochemistry

Volumn 244, Issue 1, 1997, Pages 81-88

  Vallon, Rüdiger ^a,b   Müller, Ralph ^a,b   Moosmayer, Dieter ^c   Gerlach, Elke ^c   Angel, Peter ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

^c UNIVERSITY OF STUTTGART   (Germany)

Author keywords

Baculovirus; Matrix metalloprotease; Protein protein interaction; Tissue inhibitor of metalloprotease

Indexed keywords

COLLAGENASE; RECOMBINANT ENZYME; TISSUE INHIBITOR OF METALLOPROTEINASE; ZINC;

ANIMAL CELL; ARTICLE; BACULOVIRUS; COMPLEX FORMATION; CONTROLLED STUDY; DELETION MUTANT; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HUMAN; INSECT; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN;

EID: 0031050409     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.1997.00081.x     Document Type: Article

References (43)

1. Angel, P. & Karin, M. (1991) The role of jun, fos and the AP-1 complex in cell proliferation and transformation, Biochim. Biophys. Acta 1072, 129-157.
2. Annweiler, A., Hipskind, R. A. & Wirth, T. (1991) A strategy for efficient in vitro translation using the rabbit β-globin leader sequence, Nucleic Acids Res. 19, 3750.
3. Bigg, H. F., Clark, J. M. & Cawston, T. E. (1994) Fragments of human fibroblast collagenase: interaction with metalloproteinase inhibitors and substrates, Biochim. Biophys. Acta. 1208, 157-165.
4. Birkedal-Hansen, H., Moore, W. G. I., Bodden, M. K., Windsor, L. J., Birkedal-Hansen, B., DeCarlo, A. & Engler, J. A. (1993) Matrix metalloproteinase. A review, Crit. Rev. Oral. Biol. Med. 4, 197-250.
5. Boone, T. C., Johnson, M. J., DeClerck, Y. A. & Langley, K. E. (1990) cDNA cloning and expression of a metalloproteinase inhibitor related to tissue inhibitor of metalloproteinases, Proc. Natl Acad. Sci. USA 87, 2800-2804.
6. Cawston, T. E. & Murphy, G. (1981) Mammalian collagenases, Methods Enzymol. 80, 711-722.
7. Clark, I. M. & Cawston, T. E. (1989) Fragments of human fibroblast collagenase. Purification and characterization, Biochem. J. 263, 201-206.
8. Dioszegi, M., Cannon, P. & van Wart, H. (1995) Verterbrate collagenases, Methods Enzymol. 248, 413-431.
9. Docherty, A. J. P., Lyons, A., Smith, B. J., Wright, E. M., Stephens, P. E., Harris, T. J. R., Murphy, G. & Reynolds, J. J. (1985) Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity. Nature 318, 66-69.
10. Fridman, R., Fuerst, T. R., Bird, R. E., Hoyhtya, M., Oelkuct, M., Kraus, S., Komarek, D., Liotta, L. A., Berman, M. I. & Stetler-Stevenson, W. G. (1992) Domain structure of human 72-kDa gelatinase/type IV collagenase. Characterization of proteolytic activity and identification of the tissue inhibitor of metalloproteinasa-2 (TIMP-2) binding regions, J Biol. Chem. 267, 15 398-15 405.
11. Gack, S., Vallon, R., Schaper, J., Rüther, U. & Angel, P. (1994) Phenotypical alterations in Fos-transgenic mice correlate with changes in Fos/Jun-dependent collagenase type I expression, J. Biol. Chem. 269, 10 363-10 369.
12. Goldberg, G. I., Strongin, A., Collier, I. E., Genrich, L. T. & Manner, B. L. (1992) Interaction of 92-kDa type-IV collagenase with the tissue inhibitor of metalloproteinases prevents dimerization, complex formation with interstitial collagenase, and activation of the pro-enzyme with stromelysin, J. Biol. Chem. 267, 4583-4591.
13. Grant, G. A., Eisen, A. Z., Marmer, B. L., Roswit, W. T. & Goldberg, G. I. (1987) The activation of human skin fibroblast procollagenase. Sequence identification of the major conversion products, J. Biol. Chem. 262, 5886-5889.
14. Hirose, T., Patterson, C., Pourmotabbed, T., Mainardi, C. I. & Hasty, K. A. (1993) Structure-function relationship of human neutrophil collagenase - identification of regions responsible for substrate specificity and general proteinase activity, Proc. Natl Acad. Sci. USA 90, 2569-2573.
15. Howard, E. W. & Banda, M. J. (1991) Binding of tissue inhibitor of metalloproteinases-2 to two distinct sites on human 72 kDa gelatinase. Identification of a stabilization site, J. Biol. Chem. 266, 17972-17977.
16. Knäuper, V., Osthues, A., DeClerck, Y. A., Langley, K. E., Blaser, J. & Tschesche, H. (1993) Fragmentation of human polymorphonuclearleucocyte collagenase, Biochem. J. 291, 847-854.
17. Kurschat, P., Graeve, L., Erren, A., Gatsios, P., Rose-John, S., Roeb, E., Tschesche, H., Koj, A. & Heinrich, P. C. (1995) Expression of a biologically active murine tissue inhibitor of metalloproteinases-1 (TIMP-1) in baculovirus-infected insect cells. Purification and tissue distribution in the rat, Eur. Biochem. 234, 485-491.
18. Lovejoy, B., Cleasby, A., Hassel, A. M. Longley, K., Luther, M. A., Weigl, D., McGeehan, G., McElroy, A. B., Dewry, D., Lambert, M. H. & Jordan, S. R. (1994) Structure of the catalytic domain of fibroblast collagenase complexed with an inhibitor, Science 263, 375-377.
19. Martin, G. R., Timpl, R., Müller, P. K. & Kühn, K. (1985) The genetically distinct collagens, Trends Biochem. Sci. 10, 285-287.
20. Matrisian, L. M. (1992) The matrix degrading metalloproteinases, Bioessays 14, 455-463.
21. Moosmayer, D., Gerlach, E., Bottinger, H., Scheurich, P. & Pfizenmaier, K. (1994) Expression of complete human IFN-gamma receptor and its extracellular domain in insect cells: purification and characterization of the recombinant proteins, Lymphokine Cytokine Res. 13, 147-153.
22. Murphy, G., Cockett, M. I., Stephens, P. E., Smith, B. J. & Docherty, A. J. P. (1987) Stromelysin is an activator of procollagenase. A study with natural and recombinant enzymes, Biochem. J. 248, 265-268.
23. Murphy, G., Allan, J. A., Willenbrock, F., Cockett, M. I., O'Connell, J. P. & Docherty, A. J. P. (1992) The role of the C-terminal domain in collagenase and stromelysin specificity, J. Biol. Chem. 267, 9612-9618.
24. Murphy, G. & Reynolds, J. J. (1993) Extracellular matrix degradation, in Connective tissue and its heritable disorders (Royce, P. M. & Steinmann, B., eds) pp. 287-316, John Wiley & Sons, New York.
25. Murphy, G. & Willenbrock, F. (1995) Tissue inhibitors of metalloendopeptidases, Methods Enzymol. 248, 496-510.
26. Nagase, H., Enghild, J. J., Suzuki, K. & Salvesen, G. (1990) Stepwise activation mechanisms of the precursor of matrix metalloproteinase 3 (stromelysin) by proteinases and (4-aminophenyl) mercuric acetate, Biochemistry 29, 5783-5789.
27. Nagase, H. (1994) Matrix metalloproteinases, in Contributions to nephrology: Extracellular matrix in the kidney (Koide, H. & Hayashi, T. eds) vol. 107, pp. 85-93, Karger, Basel.
28. Netzel-Arnett, S., Salari, A., Goli, U. B. & van Wart, H. E. (1994) Evidence for a triple helix recognition site in the hemopexin domains of human fibroblast and neutrophil interstitial collagenases, Ann. NY Acad. Sci. 732, 22-30.
29. O'Hare, M. C., Clarke, N. J. & Cawston, T. E. (1992) Production in Escherichia coli of porcine type I collagenase as a fusion protein with β-galactosidase, Gene 111, 245-248.
30. Pavloff, N., Staskus, P. W., Kishnani, N. S. & Hawkes, S. P. (1992) A new inhibitor of metalloproteinases from chicken - ChIMP-3 - a 3rd member of the TIMP family, J. Biol. Chem. 267, 17 321-17 326.
31. Sang, Q. A. & Douglas, D. A. (1996) Computational sequence analysis of matrix metalloproteinases, J. Protein Chem. 15, 137-160.
32. Schnierer, S., Kleine, T., Gote, T., Hillemann, A., Knäuper, V. & Tschesche, H. (1993) The recombinant catalytic domain of human neutrophil collagenase lacks type I collagen substrate specificity, Biochem. Biophys. Res. Commun. 191, 319-326.
33. Schönthal, A., Herrlich, P., Rahmsdorf, H. J. & Ponta, H. (1988) Requirement for fos gene expression in the transcriptional activation of collagenase by other oncogenes and phorbol esters, Cell 54, 325-334.
34. Schreiber, M., Baumann, B., Cotten, M., Angel, P. & Wagner, E. (1995) Fos is an essential component of the mammalian UV response, EMBO J. 14, 5338-5349.
35. Smith, D. B. & Johnson, K. S. (1988) Single-step purification of polypeptides expressed in Escherichia coli as fusions with gluthathione S-transferase, Gene 67, 31-40.
36. Springman, E. B., Angleton, E. L., Birkedal-Hansen, H. & van Wart, H. E. (1990) Multiple modes of activation of latent human fibroblast collagenase. Evidence for the role of a Cys-73 active-site zinc complex in latency and a 'cysteine switch' mechanism for activation, Proc. Natl Acad. Sci. USA 87, 364-368.
37. Strongin, A. Y., Collier, I., Bannikov, G., Manner, B. L., Grant, G. A. & Goldberg, G. I. (1995) Mechanism of cell surface activation of 72-kDa type IV collagenase, J. Biol. Chem. 270, 5331-5338.
38. Suzuki, K., Enghild, J. J., Morodomi, T., Salvesen, G. & Nagase, H. (1990) Mechanisms of activation of tissue procollagenase by matrix metalloproteinase 3 (stromelysin), Biochemistry 29, 10261-10270.
39. Whitham, S. E., Murphy, G., Angel, P., Rahmsdorf, H. J., Smith, B. J., Lyons, A., Harris, T. J., Reynolds, J. J., Herrlich, P. & Docherty, A. J. (1986) Comparison of human stromelysin and collagenase by cloning and sequence analysis, Biochem. J. 240, 913-916.
40. Wilhelm, S. M., Eisen, A. Z., Teter, M., Clark, S. D., Kronberger, M. & Goldberg, G. (1986) Human fibroblast collagenase: glycosylation and tissue specific levels of enzyme synthesis, Proc. Natl Acad. Sci. USA 83, 3756-3760.
41. Willenbrock, F., Crabbe, T., Slocombe, P. M., Sutton, C. W., Docherty, A. J., Cockett, M. I., O'Shea, M., Brocklehurst, K., Philips, I. R. & Murphy, G. (1993) The activity of the tissue inhibitors of metalloproteinases is regulated by C-terminal domain interactions: a kinetic analysis of the inhibition of gelatinase A, Biochemistry 32, 4330-4337.
42. Windsor, L. J., Birkedal-Hansen, H., Birkedal-Hansen, B. & Engler, J. A. (1991) An internal cysteine plays a role in the maintenance of the latency of human fibroblast collagenase, Biochemistry 30, 641-647.
43. Windsor, L. J., Bodden, M. K., Birkedal-Hansen, B., Engler, J. A. & Birkedal-Hansen, H. (1994) Mutational analysis of residues in and around the active site of human fibroblast-type collagenase, J. Biol. Chem. 269, 26 201-26 207.