Nicotinamide- and caspase-mediated inhibition of poly(ADP-ribose) polymerase are associated with p53-independent cell cycle (G2) arrest and apoptosis

Molecular and Cellular Biochemistry

Volumn 243, Issue 1-2, 2003, Pages 113-122

  Saldeen, Johan ^a   Tillmar, Linda ^a   Karlsson, Ella ^a   Welsh, Nils ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Bcl 2; Beta cells; Cytokines; JC 1; Mitochondrial transmembrane potential; Nitric oxide; Tumor cells

Indexed keywords

3 AMINOBENZAMIDE; CASPASE; CYTOKINE; NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NITRIC OXIDE; PROTEIN BCL 10; PROTEIN P53;

ADENOSINE DIPHOSPHATE RIBOSYLATION; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE G2 PHASE; CONTROLLED STUDY; DNA REPAIR; DNA REPLICATION; ENZYME DEGRADATION; ENZYME INHIBITION; EPITHELIUM CELL; HUMAN; HUMAN CELL; MEMBRANE POTENTIAL; MESENCHYME CELL; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; PANCREAS TUMOR; PROTEIN FUNCTION; PROTEIN LOCALIZATION; TUMOR CELL;

ANIMALS; APOPTOSIS; BENZAMIDES; CASPASES; CELL CYCLE; CELL NUCLEUS; CYTOKINES; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; G2 PHASE; HELA CELLS; HUMANS; IMMUNOBLOTTING; JURKAT CELLS; MEMBRANE POTENTIALS; MICE; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; NIACINAMIDE; NIH 3T3 CELLS; NITRIC OXIDE; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-BCL-2; RADIATION-SENSITIZING AGENTS; TIME FACTORS; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS;

ANIMALIA;

EID: 0037281153     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1021651811345     Document Type: Article

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