Electrogenic ion transport in mammalian colon involves an ammonia-sensitive apical membrane K+ conductance

Digestive Diseases and Sciences

Volumn 48, Issue 1, 2003, Pages 116-125

  Mayol, Julio M ^a,e   Alarma Estrany, Pilar ^a   O'Brien, Timothy C ^b   Song, Jaekyung C ^c   Prasad, Madhu ^d   Adame Navarrete, Yolanda ^a   Fernández Represa, Jesus A ^a   Mun, Edward C ^b   Matthews, Jeffrey B ^c  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^d OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^e HOSPITAL CLÍNICO SAN CARLOS   (Spain)

Author keywords

Ammonia; Chloride secretion; Electrophysiology; Human colon; Potassium channels; Rat distal colon

Indexed keywords

POTASSIUM CHANNEL;

ANIMAL TISSUE; APICAL MEMBRANE; ARTICLE; BASOLATERAL MEMBRANE; CELL FUNCTION; COLON MUCOSA; ELECTROLYTE BALANCE; ELECTROPHYSIOLOGY; EPITHELIUM CELL; FLUID BALANCE; HUMAN; HUMAN TISSUE; ION TRANSPORT; MEMBRANE CONDUCTANCE; NONHUMAN; POTASSIUM CONDUCTANCE; PRIORITY JOURNAL; RAT; RECYCLING;

AMMONIA; ANIMALS; CHLORIDE CHANNELS; COLON; ELECTROPHYSIOLOGY; HUMANS; INTESTINAL MUCOSA; ION TRANSPORT; MALE; POTASSIUM CHANNELS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0037280479     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1021746717702     Document Type: Article

References (39)

1. Barrett KE: Positive and negative regulation of chloride secretion in T84 cells. Am J Physiol 265:C859-C868, 1993.
2. + transport in a human colonoci epithelial cell line. J Biol Chem 260:14163-14166, 1985
3. - transport. Asymmetric effects of apical and basolateral exposure and implications for epithelial barrier function. J Clin Invest 96(5):2142-2151, 1995
4. + conductance. Am J Physiol 277(3 Pt 1):G521-G532, 1999
5. Mayol JM, Hrnjez BJ, Akbarali HI, Song JC, Smith JA, Matthews JB: Ammonia effect on calcium-activated chloride secretion in T84 intestinal epithelial monolayers. Am J Physiol 273(2 Pt 1):634-642, 1997
6. O'Brien TC, Riegler M, Mun EC, Prasad M, Pothoulakis C, Matthews JB: Ammonia inhibitis regulated chloride secretion in in-vitro human colon. Gastroenterology 114(suppl 1):S3355, 1998
7. + in isolated, perfused colonic crypts. Proc Natl Acad Sci USA 92(25):11573-11577, 1995
8. +)-ATPase in apical membranes from rat distal colon. J Biol Chem 274(28):19693-19698, 1999
9. + and cell pH in colonic crypts of the rat. Pfleugers Arch 438(4):508-515, 1999
10. Hagen SJ, Wu H, Morrison SW: NH(4)Cl inhibition of acid secretion: possible involvement of an apical K(+) channel in bullfrog oxyntic cells. Am J Physiol Gastrointest Liver Physiol 279(2):G400-G410, 2000
11. Mall M, Bleich M, Schurlein M, Kuhr J, Seydewitz HH, Brandis M, Greger R, Kunzelmann K: Cholinergin ion secretion in human colon requires coactivatlon by cAMP. Am J Physiol 275(Gastrointest Liver Physiol 38):G1274-G1281, 1998
12. - conductances in the distal colon of the rat. Gen Pharmacol 31(3):337-342, 1998
13. Rolfe VE, Levin RJ: Neural and non-neural activation of electrogenic secretion by 5-hydroxytryptamine in the rat ileum. Acta Physiol Scand 162:469-474, 1998
14. Stoner MC, Scherr AM, Lee JA, Wolfe LG, Kellum JM: Nitric oxide is a neurotransmitter in the chloride secretory response to serotonin in rat colon. Surgery 128(2):240-245, 2000
15. Prasad M, Ito S, Silen W: Functional studies of in vitro rat distal colon before and after restitution. Surgery 121(4):430-439, 1997
16. +-ATPase. Semin Nephrol 19(5):405-414, 1999
17. Schroeder BC, Waldegger S, Fehr S, Bleich M, Warth R, Greger R, Jentsch TJ: A constitutively open potassium channel formed by KCNQ1 and KCNE3. Nature 403(6766): 196-199, 2000
18. + channel KVLQT1. J. Membr Biol 179(2):155-164, 2001
19. Hardcastle J, Hardcastle PT, Noble JM: The secretory action of barium chloride in rat colon. J Physiol 361:19-33, 1985
20. + conductances. Demonstration of efficacy in intact rabbit colon and in an in vivo mouse model of cholera. J Clin Invest 100(12):3111-3120, 1997
21. + channels. Clin Exp Pharmacol Physiol 28(1-2):79-83, 2001
22. - transport. J Membr Biol 110(2): 139-146, 1989
23. Brzuszczak IM, Zhao J, Bell C, Stiel D, Fielding I, Percy J, Smith R, O'laughlin EV: Cyclic AMP-dependent anion secretion in human small and large intestine. J Gastroenterol Hepatol 11(9):804-810, 1996
24. Riegler M, Castagliuolo I, Wang C, Wlk M, Sogukoglu T, Wenzl E, Matthews JB, Pothoulakis C: Neurotensin stimulates Cl(-) secretion in human colonic mucosa In vitro: role of adenosine. Gastroenterology 119(2):348-357, 2000
25. Schultheiss G, Horger S, Diener M: The bumetanide-resistant part of forskolin-induced anion secretion in rat colon. Acta Physiol Scand 164(2):219-228, 1998
26. + secretion in rat distal colon by conductance scanning. J Physiol 507(Pt2):561-570, 1998
27. + transport in the rat distal colon. Br J Pharmacol 118(6):1477-1487, 1996
28. + conductances in rat colon. Br J Pharmacol 122(1):87-94, 1997
29. Mall M, Wissner A, Seydewitz HH, Kuehr J, Brandis M, Greger R, Kunzelmann K: Defective cholinergic Cl(-) secretion and detection of K(+) secretion in rectal biopsies from cystic fibrosis patients. Am J Physiol (Gastrointest Liver Physiol) 278(4):G617-G624, 2000
30. Ikuma M, Binder HJ, Geibel J: Role of apical H-K exchange and basolateral K channel in the regulation of intracellular pH in rat distal colon crypt cells. J Membr Biol 166(3):205-212, 1998
31. + currents in HeLa cells. Biochim Biophys Acta 1284(2):119-121, 1996
32. Yang IC, Scherz MW, Bahinski A, Bennett PB, Murray KT: Stereoselective interactions of the enantiomers of chromanol 293B with human voltage-gated potassium channels. J Pharmacol Exp Ther 294(3):955-962, 2000
33. - current. Naunyn Schmiedebergs Arch Pharmacol 363(6):590-596, 2001
34. Sandle GI, McNicholas CM, Lomax RB: Potassium channels in colonic crypts. Lancet 343(8888):23-25, 1994
35. + channel involvement in forskolin-activated chloride secretion in human colon. J Physiol (London) 519(Pt 1):251-260, 1999
36. Pacha J, Popp M, Capek K: Potassium secretion by neonatal rat distal colon. Pfeugers Arch 410(4-5):362-368, 1987
37. + channel KCNQ1 is essential for gastric acid secretion. Gastroenterology 120(6):1363-1371, 2001
38. + channels co-localised with CFTR in the apical membrane of an exocrine gland acinus: possible involvement in secretion. Pfleugers Arch 442(1): 1-11, 2001
39. Shieh RC, Lee YL: Ammonium ions induce inactivation of Kir2.1 potassium channels expressed in Xenopus oocytes. J Physiol (London) 535(2):359-379, 2001