NH4Cl inhibition of acid secretion: Possible involvement of an apical K+ channel in bullfrog oxyntic cells

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 279, Issue 2 42-2, 2000, Pages

  Hagen, Susan J ^a   Wu, Hui ^a   Morrison, Sarah W ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

Ammonia; Gastric mucosa; Rana catesbeiana

Indexed keywords

ADENOSINE TRIPHOSPHATE; AMMONIUM CHLORIDE; POTASSIUM CHANNEL;

ANIMAL CELL; ARTICLE; BASOLATERAL MEMBRANE; BULLFROG; CELL STIMULATION; CONTROLLED STUDY; ION TRANSPORT; NONHUMAN; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; STOMACH ACID SECRETION; STOMACH MUCOSA; STOMACH PARIETAL CELL;

EID: 0033850971     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.2000.279.2.g400     Document Type: Article

References (41)

1. A method for preparing isolated glands from the rabbit gastric mucosa
2. Unique permeability barrier of the apical surface of parietal and chief cells in isolated perfused gastric glands
3. How does Helicobacterpylori cause mucosal damage? Its effect on acid and gastric physiology
4. Cell survival in rabbit gastric glands: Effect of extracellular pH, osmolarity, and anoxia
5. Sulfonylurea effects on acid and pepsinogen secretion in isolated rabbit gastric glands
6. + currents in HeLa cells
7. Chloride transport by gastric mucosa
8. +-ATPase activity and glucose oxidation in gastric glands
9. Gastric acid secretion in chronic uraemia and after renal transplantation
10. Localization of brush border cytoskeletal proteins in gastric oxynticopeptic cells from the bullfrog Rana catesbeiana
11. + exchangers on acid secretion in the rat gastric mucosa sheet preparation
12. - exchanger, 4,4'-diisothiocyanostilbene-2,2' -disulfonic acid
13. +-channel Kir4.1 participates in gastric acid secretion
14. + channels
15. Ammonium transport in the kidney
16. A study of the acid gastric secretion in portal hypertension
17. Ammonia effect on calcium-activated chloride secretion in T84 intestinal epithelial monolayers
18. - secretion in vitro frog and piglet gastric mucosa
19. Further evidence of the toxic effect of ammonia produced by Helicobacter pylori urease on human epithelial cells
20. + channel activity in bullfrog oxyntic cells
21. Helicobacter pylori factors associated with disease development
22. - exchange by stimulation of acid secretion in the parietal cell
23. Gastric ammonia has a potent ulcerogenic action on the rat stomach
24. Hypergastrinemia and achlorhydria in chronic renal failure
25. Reversal by potassium of an effect of barium on the frog gastric mucosa
26. Selective increase of the permeability of polarized epithelial monolayers by Helicobacter pylori vacuolating cytotoxin
27. - transport: Asymmetric effects of apical and basolateral exposure and implications for epithelial barrier function
28. - secretion by frog gastric mucosa
29. - conductances in apical membrane vesicles from stimulated rabbit oxyntic cells
30. Cytotoxicity of Helicobacter pylori on human gastric epithelial cells in vitro: Role of cytotoxin(s) and ammonia
31. - secretion by polarized monolayers of human colonic epithelial cells
32. + conductances
33. Demonstration of a barium-potassium antagonism on lumen side of in vitro frog stomach
34. 2+ on frog stomach
35. Effects of barium on the in vitro frog gastric mucosa
36. Severity of Helicobacter-induced gastric injury correlates with gastric juice ammonia
37. Mechanism of gastric mucosal damage induced by ammonia
38. Hyperpermeability and ATP depletion induced by chronic hypoxia or glycolytic inhibition in Caco-2(BBe) monolayers
39. - conductances in the apical membrane from secreting oxyntic cells are concurrently inhibited by divalent cations
40. Effects of ammonium ion and ammonia on function and morphology of in vitro frog gastric mucosa
41. Helicobacter pylori vacuolating cytotoxin (Vac A) increases paracellular permeability across the gastric surface mucous cell monolayers