메뉴 건너뛰기




Volumn 15, Issue 1, 2003, Pages 11-16

Experimental autoimmune myasthenia gravis in naive non-obese diabetic (NOD/LtJ) mice: Susceptability associated with natural IgG antilbodies to the acetylcholine receptor

Author keywords

Autoantibodies; Autoimmunity; Homunculus

Indexed keywords

CHOLINERGIC RECEPTOR; GAMMA INTERFERON; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G2B;

EID: 0037253847     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/dxg003     Document Type: Review
Times cited : (12)

References (51)
  • 1
    • 0035508638 scopus 로고    scopus 로고
    • Autoantibody patterns in diabetes-prone NOD mice and in standard C57BL/6 mice
    • Quintana, F. J. and Cohen, I. R. 2001. Autoantibody patterns in diabetes-prone NOD mice and in standard C57BL/6 mice. J. Autoimmun. 17:191.
    • (2001) J. Autoimmun. , vol.17 , pp. 191
    • Quintana, F.J.1    Cohen, I.R.2
  • 3
    • 17744416538 scopus 로고    scopus 로고
    • Antibody to acetylcholine receptor in myasthenia gravis: Prevalence, clinical correlates, and diagnostic value. 1975
    • Lindstrom, J. M., Seybold, M. E., Lennon, V. A., Whittingham, S. and Duane, D. D. 1998. Antibody to acetylcholine receptor in myasthenia gravis: prevalence, clinical correlates, and diagnostic value. 1975. Neurology 51:933.
    • (1998) Neurology , vol.51 , pp. 933
    • Lindstrom, J.M.1    Seybold, M.E.2    Lennon, V.A.3    Whittingham, S.4    Duane, D.D.5
  • 4
    • 0032722304 scopus 로고    scopus 로고
    • Organ-specific autoantibodies with muscle weakness
    • Al-Lozi, M. and Pestronk, A. 1999. Organ-specific autoantibodies with muscle weakness. Curr. Opin. Rheumatol. 11:483.
    • (1999) Curr. Opin. Rheumatol. , vol.11 , pp. 483
    • Al-Lozi, M.1    Pestronk, A.2
  • 5
    • 0034053126 scopus 로고    scopus 로고
    • Oral administration of a dual analog of two myasthenogenic T cell epitopes down-regulates experimental autoimmune myasthenia gravis in mice
    • Paas-Rozner, M., Dayan, M., Paas, Y., Changeux, J. P., Wirguin, I., Sela, M. and Mozes, E. 2000. Oral administration of a dual analog of two myasthenogenic T cell epitopes down-regulates experimental autoimmune myasthenia gravis in mice. Proc. Natl Acad. Sci. USA 97:2168.
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 2168
    • Paas-Rozner, M.1    Dayan, M.2    Paas, Y.3    Changeux, J.P.4    Wirguin, I.5    Sela, M.6    Mozes, E.7
  • 6
    • 0034548005 scopus 로고    scopus 로고
    • Vaccination with empty plasmid DNA or CpG oligonucleotide inhibits diabetes in nonobese diabetic mice: Modulation of spontaneous 60-kDa heat shock protein autoimmunity
    • Quintana, F. J., Rotem, A., Carmi, P. and Cohen, I. R. 2000. Vaccination with empty plasmid DNA or CpG oligonucleotide inhibits diabetes in nonobese diabetic mice: modulation of spontaneous 60-kDa heat shock protein autoimmunity. J. Immunol. 165:6148.
    • (2000) J. Immunol. , vol.165 , pp. 6148
    • Quintana, F.J.1    Rotem, A.2    Carmi, P.3    Cohen, I.R.4
  • 7
    • 0034632162 scopus 로고    scopus 로고
    • Interleukin-12 enhances clinical experimental autoimmune myasthenia gravis in susceptible but not resistant mice
    • Sitaraman, S., Metzger, D. W., Belloto, R. J., Infante, A. J. and Wall, K. A. 2000. Interleukin-12 enhances clinical experimental autoimmune myasthenia gravis in susceptible but not resistant mice. J. Neuroimmunol. 107:73.
    • (2000) J. Neuroimmunol. , vol.107 , pp. 73
    • Sitaraman, S.1    Metzger, D.W.2    Belloto, R.J.3    Infante, A.J.4    Wall, K.A.5
  • 9
    • 0025293535 scopus 로고
    • Prevention of type I diabetes in NOD mice by adjuvant immunotherapy
    • Sadelain, M. W., Qin, H. Y., Lauzon, J. and Singh, B. 1990. Prevention of type I diabetes in NOD mice by adjuvant immunotherapy. Diabetes 39:583.
    • (1990) Diabetes , vol.39 , pp. 583
    • Sadelain, M.W.1    Qin, H.Y.2    Lauzon, J.3    Singh, B.4
  • 10
    • 0027314785 scopus 로고
    • Complete Freund's adjuvant-induced T cells prevent the development and adoptive transfer of diabetes in nonobese diabetic mice
    • Qin, H. Y., Sadelain, M. W., Hitchon, C., Lauzon, J. and Singh, B. 1993. Complete Freund's adjuvant-induced T cells prevent the development and adoptive transfer of diabetes in nonobese diabetic mice. J. Immunol. 150:2072.
    • (1993) J. Immunol. , vol.150 , pp. 2072
    • Qin, H.Y.1    Sadelain, M.W.2    Hitchon, C.3    Lauzon, J.4    Singh, B.5
  • 11
    • 0026559333 scopus 로고
    • A T-cell dormant state in the autoimmune process of nonobese diabetic mice treated with complete Freund's adjuvant
    • Ulaeto, D., Lacy, P. E., Kipnis, D. M., Kanagawa, O. and Unanue, E. R. 1992. A T-cell dormant state in the autoimmune process of nonobese diabetic mice treated with complete Freund's adjuvant. Proc. Natl Acad. Sci. USA 89:3927.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 3927
    • Ulaeto, D.1    Lacy, P.E.2    Kipnis, D.M.3    Kanagawa, O.4    Unanue, E.R.5
  • 12
    • 0018189697 scopus 로고
    • Role of complement in the pathogenesis of experimental autoimmune myasthenia gravis
    • Lennon, V. A., Seybold, M. E., Lindstrom, J. M., Cochrane, C. and Ulevitch, R. 1978. Role of complement in the pathogenesis of experimental autoimmune myasthenia gravis. J. Exp. Med. 147:973.
    • (1978) J. Exp. Med. , vol.147 , pp. 973
    • Lennon, V.A.1    Seybold, M.E.2    Lindstrom, J.M.3    Cochrane, C.4    Ulevitch, R.5
  • 13
    • 0025285780 scopus 로고
    • Acetylcholine receptor gene expression in experimental autoimmune myasthenia gravis
    • Asher, O., Neumann, D., Witzemann, V. and Fuchs, S. 1990. Acetylcholine receptor gene expression in experimental autoimmune myasthenia gravis. FEBS Lett. 267:231.
    • (1990) FEBS Lett. , vol.267 , pp. 231
    • Asher, O.1    Neumann, D.2    Witzemann, V.3    Fuchs, S.4
  • 14
    • 0017582747 scopus 로고
    • Myasthenic immunoglobulin accelerates acetylcholine receptor degradation
    • Kao, I. and Drachman, D. B. 1977. Myasthenic immunoglobulin accelerates acetylcholine receptor degradation. Science 196:527.
    • (1977) Science , vol.196 , pp. 527
    • Kao, I.1    Drachman, D.B.2
  • 15
    • 0033729479 scopus 로고    scopus 로고
    • Helper T cells in antibody-mediated, organ-specific autoimmunity
    • Elson, C. J. and Barker, R. N. 2000. Helper T cells in antibody-mediated, organ-specific autoimmunity. Curr. Opin. Immunol. 12:664.
    • (2000) Curr. Opin. Immunol. , vol.12 , pp. 664
    • Elson, C.J.1    Barker, R.N.2
  • 16
    • 0030878993 scopus 로고    scopus 로고
    • Interferon gamma (IFN-gamma) is necessary for the genesis of acetylcholine receptor-induced clinical experimental autoimmune myasthenia gravis in mice
    • Balasa, B., Deng, C., Lee, J., Bradley, L. M., Dalton, D. K., Christadoss, P. and Sarvetnick, N. 1997. Interferon gamma (IFN-gamma) is necessary for the genesis of acetylcholine receptor-induced clinical experimental autoimmune myasthenia gravis in mice. J. Exp. Med. 186:385.
    • (1997) J. Exp. Med. , vol.186 , pp. 385
    • Balasa, B.1    Deng, C.2    Lee, J.3    Bradley, L.M.4    Dalton, D.K.5    Christadoss, P.6    Sarvetnick, N.7
  • 18
    • 0026465192 scopus 로고
    • A two-signal model for regulation of immunoglobulin isotype switching
    • Purkerson, J. and Isakson, P. 1992. A two-signal model for regulation of immunoglobulin isotype switching. FASEB J. 6:3245.
    • (1992) FASEB J. , vol.6 , pp. 3245
    • Purkerson, J.1    Isakson, P.2
  • 19
    • 0030953146 scopus 로고    scopus 로고
    • Cellular mRNA expression of interferon-gamma (IFN-gamma), IL-4 and IL-10 relates to resistance to experimental autoimmune myasthenia gravis (EAMG) in young Lewis rats
    • Shi, F. D., Zhang, G. X., Bai, X. F., Van der Meide, P. H. and Link, H. 1997. Cellular mRNA expression of interferon-gamma (IFN-gamma), IL-4 and IL-10 relates to resistance to experimental autoimmune myasthenia gravis (EAMG) in young Lewis rats. Clin. Exp. Immunol. 108:523.
    • (1997) Clin. Exp. Immunol. , vol.108 , pp. 523
    • Shi, F.D.1    Zhang, G.X.2    Bai, X.F.3    Van der Meide, P.H.4    Link, H.5
  • 20
    • 0017145379 scopus 로고
    • Strain differences in the autoimmune response of mice to acetylcholine receptors
    • Fuchs, S., Nevo, D., Tarrab-Hazdai, R. and Yaar, I. 1976. Strain differences in the autoimmune response of mice to acetylcholine receptors. Nature 263:329.
    • (1976) Nature , vol.263 , pp. 329
    • Fuchs, S.1    Nevo, D.2    Tarrab-Hazdai, R.3    Yaar, I.4
  • 21
    • 0018887157 scopus 로고
    • Linkage between the frequency of muscular weakness and loci that regulate immune responsiveness in murine experimental myasthenia gravis
    • Berman, P. W. and Patrick, J. 1980. Linkage between the frequency of muscular weakness and loci that regulate immune responsiveness in murine experimental myasthenia gravis. J. Exp. Med. 152:507.
    • (1980) J. Exp. Med. , vol.152 , pp. 507
    • Berman, P.W.1    Patrick, J.2
  • 22
    • 0018864218 scopus 로고
    • Experimental myasthenia gravis. A murine system
    • Berman, P. W. and Patrick, J. 1980. Experimental myasthenia gravis. A murine system. J. Exp. Med. 151:204.
    • (1980) J. Exp. Med. , vol.151 , pp. 204
    • Berman, P.W.1    Patrick, J.2
  • 24
    • 0024997357 scopus 로고
    • Fine specificity and HLA restriction of myelin basic protein-specific cytotoxic T cell lines from multiple sclerosis patients and healthy individuals
    • Martin, R., Jaraquemada, D., Flerlage, M., Richert, J., Whitaker, J., Long, E. O., McFarlin, D. E. and McFarland, H. F. 1990. Fine specificity and HLA restriction of myelin basic protein-specific cytotoxic T cell lines from multiple sclerosis patients and healthy individuals. J. Immunol. 145:540.
    • (1990) J. Immunol. , vol.145 , pp. 540
    • Martin, R.1    Jaraquemada, D.2    Flerlage, M.3    Richert, J.4    Whitaker, J.5    Long, E.O.6    McFarlin, D.E.7    McFarland, H.F.8
  • 25
    • 0028882422 scopus 로고
    • Autoreactive T cells in healthy individuals show tolerance in vitro with characteristics similar to but distinct from clonal anergy
    • Filion, M. C., Bradley, A. J., Devine, D. V., Decary, F. and Chartrand, P. 1995. Autoreactive T cells in healthy individuals show tolerance in vitro with characteristics similar to but distinct from clonal anergy. Eur. J. Immunol. 25:3123.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 3123
    • Filion, M.C.1    Bradley, A.J.2    Devine, D.V.3    Decary, F.4    Chartrand, P.5
  • 26
    • 0029817658 scopus 로고    scopus 로고
    • Presence in peripheral blood of healthy individuals of autoreactive T cells to a membrane antigen present on bone marrow-derived cells
    • Filion, M. C., Proulx, C., Bradley, A. J., Devine, D. V., Sekaly, R. P., Decary, F. and Chartrand, P. 1996. Presence in peripheral blood of healthy individuals of autoreactive T cells to a membrane antigen present on bone marrow-derived cells. Blood 88:2144.
    • (1996) Blood , vol.88 , pp. 2144
    • Filion, M.C.1    Proulx, C.2    Bradley, A.J.3    Devine, D.V.4    Sekaly, R.P.5    Decary, F.6    Chartrand, P.7
  • 28
    • 0022931326 scopus 로고
    • Antibody repertoires of normal BALB/c mice: B lymphocyte populations defined by state of activation
    • Holmberg, D., Freitas, A. A., Portnoi, D., Jacquemart, F., Avrameas, S. and Coutinho, A. 1986. Antibody repertoires of normal BALB/c mice: B lymphocyte populations defined by state of activation. Immunol. Rev. 93:147.
    • (1986) Immunol. Rev. , vol.93 , pp. 147
    • Holmberg, D.1    Freitas, A.A.2    Portnoi, D.3    Jacquemart, F.4    Avrameas, S.5    Coutinho, A.6
  • 30
    • 0141691773 scopus 로고
    • Evidence for a functional idiotypic network among natural antibodies in normal mice
    • Lundkvist, I., Coutinho, A., Varela, F. and Holmberg, D. 1989. Evidence for a functional idiotypic network among natural antibodies in normal mice. Proc. Natl Acad. Sci. USA 86:5074.
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 5074
    • Lundkvist, I.1    Coutinho, A.2    Varela, F.3    Holmberg, D.4
  • 32
    • 0025905663 scopus 로고
    • Natural autoantibodies: From 'horror autotoxicus' to 'gnothi seauton'
    • Avrameas, S. 1991. Natural autoantibodies: from 'horror autotoxicus' to 'gnothi seauton'. Immunol. Today 12:154.
    • (1991) Immunol. Today , vol.12 , pp. 154
    • Avrameas, S.1
  • 33
    • 0016675949 scopus 로고
    • Hypothesis. Auto-antibodies and immunological theories: An analytical review
    • Grabar, P. 1975. Hypothesis. Auto-antibodies and immunological theories: an analytical review. Clin. Immunol. Immunopathol. 4:453.
    • (1975) Clin. Immunol. Immunopathol. , vol.4 , pp. 453
    • Grabar, P.1
  • 34
    • 0034508025 scopus 로고    scopus 로고
    • Natural antibodies and complement link innate and acquired immunity
    • Ochsenbein, A. F. and Zinkernagel, R. M. 2000. Natural antibodies and complement link innate and acquired immunity. Immunol. Today 21:624.
    • (2000) Immunol. Today , vol.21 , pp. 624
    • Ochsenbein, A.F.1    Zinkernagel, R.M.2
  • 36
    • 0022919570 scopus 로고
    • Natural autoantibodies might prevent autoimmune disease
    • Cohen, I. R. and Cooke, A. 1986. Natural autoantibodies might prevent autoimmune disease. Immunol. Today 7:363.
    • (1986) Immunol. Today , vol.7 , pp. 363
    • Cohen, I.R.1    Cooke, A.2
  • 37
    • 0026058789 scopus 로고
    • Monoclonal, natural antibodies prevent development of diabetes in the non-obese diabetic (NOD) mouse
    • Andersson, A., Forsgren, S., Soderstrom, A. and Holmberg, D. 1991. Monoclonal, natural antibodies prevent development of diabetes in the non-obese diabetic (NOD) mouse. J. Autoimmun. 4:733.
    • (1991) J. Autoimmun. , vol.4 , pp. 733
    • Andersson, A.1    Forsgren, S.2    Soderstrom, A.3    Holmberg, D.4
  • 38
    • 0033378857 scopus 로고    scopus 로고
    • Autoimmune maintenance and neuroprotection of the central nervous system
    • Cohen, I. R. and Schwartz, M. 1999. Autoimmune maintenance and neuroprotection of the central nervous system. J. Neuroimmunol. 100: 111.
    • (1999) J. Neuroimmunol. , vol.100 , pp. 111
    • Cohen, I.R.1    Schwartz, M.2
  • 39
    • 0029032317 scopus 로고
    • Analysis of the normal human IgG antibody repertoire. Evidence that IgG autoantibodies of healthy adults recognize a limited and conserved set of protein antigens in homologous tissues
    • Mouthon, L., Haury, M., Lacroix-Desmazes, S., Barreau, C., Coutinho, A. and Kazatchkine, M. D.1995. Analysis of the normal human IgG antibody repertoire. Evidence that IgG autoantibodies of healthy adults recognize a limited and conserved set of protein antigens in homologous tissues. J. Immunol. 154:5769.
    • (1995) J. Immunol. , vol.154 , pp. 5769
    • Mouthon, L.1    Haury, M.2    Lacroix-Desmazes, S.3    Barreau, C.4    Coutinho, A.5    Kazatchkine, M.D.6
  • 41
    • 0035554676 scopus 로고    scopus 로고
    • Regulatory T cells in the control of immune pathology
    • Maloy, K. J. and Powrie, F. 2001. Regulatory T cells in the control of immune pathology. Nat. Immunol. 2:816.
    • (2001) Nat. Immunol. , vol.2 , pp. 816
    • Maloy, K.J.1    Powrie, F.2
  • 43
    • 0021997185 scopus 로고
    • Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease
    • Sakaguchi, S., Fukuma, K., Kuribayashi, K. and Masuda, T. 1985. Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease. J. Exp. Med. 161:72.
    • (1985) J. Exp. Med. , vol.161 , pp. 72
    • Sakaguchi, S.1    Fukuma, K.2    Kuribayashi, K.3    Masuda, T.4
  • 44
  • 45
    • 0004092095 scopus 로고    scopus 로고
    • Tending Adam's Garden: Evolving the Cognitive Immune Self
    • Academic Press, London
    • Cohen, I, R. 2000. Tending Adam's Garden: Evolving the Cognitive Immune Self. Academic Press, London.
    • (2000)
    • Cohen, I.R.1
  • 46
    • 0026439389 scopus 로고
    • The cognitive paradigm and the immunological homunculus
    • Cohen, I. R. 1992. The cognitive paradigm and the immunological homunculus. Immunol. Today 13:490.
    • (1992) Immunol. Today , vol.13 , pp. 490
    • Cohen, I.R.1
  • 47
    • 85003722383 scopus 로고
    • The Clonal Selection Theory of Acquired Immunity Cambridge University Press, Cambridge
    • Burnet, F. M. 1959. The Clonal Selection Theory of Acquired Immunity Cambridge University Press, Cambridge.
    • (1959)
    • Burnet, F.M.1
  • 48
    • 0000337323 scopus 로고    scopus 로고
    • Induction of a multiple sclerosis-like disease in mice with an immunodominant epitope of myelin oligodendrocyte glycoprotein
    • Slavin, A., Ewing, C., Liu, J., Ichikawa, M., Slavin, J. and Bernard, C. C. 1998. Induction of a multiple sclerosis-like disease in mice with an immunodominant epitope of myelin oligodendrocyte glycoprotein. Autoimmunity 28:109.
    • (1998) Autoimmunity , vol.28 , pp. 109
    • Slavin, A.1    Ewing, C.2    Liu, J.3    Ichikawa, M.4    Slavin, J.5    Bernard, C.C.6
  • 50
    • 0035944844 scopus 로고    scopus 로고
    • [Beta]-cell function in new-onset type 1 diabetes and immunomodulation with a heat-shock protein peptide (DiaPep277): A randomised, double-blind, phase II trial
    • Raz, I., Elias, D., Avron, A., Tamir, M., Metzger, M. and Cohen, I. R. 2001. [Beta]-cell function in new-onset type 1 diabetes and immunomodulation with a heat-shock protein peptide (DiaPep277): a randomised, double-blind, phase II trial. Lancet 358:1749.
    • (2001) Lancet , vol.358 , pp. 1749
    • Raz, I.1    Elias, D.2    Avron, A.3    Tamir, M.4    Metzger, M.5    Cohen, R.6
  • 51
    • 0033231305 scopus 로고    scopus 로고
    • Assessment of animal models for MS and demyelinating disease in the design of rational-therapy
    • Steinman, L. 1999. Assessment of animal models for MS and demyelinating disease in the design of rational-therapy. Neuron 24:511.
    • (1999) Neuron. , vol.24 , pp. 511
    • Steinman, L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.