메뉴 건너뛰기




Volumn 116, Issue 1, 2003, Pages 61-71

EhPAK, a member of the p21-activated kinase family, is involved in the control of Entamoeba histolytica migration and phagocytosis

Author keywords

Amoebiasis; Pseudopod; Quantitative imaging; Rac; Serine threonine kinase

Indexed keywords

PROTEIN CDC42; PROTEIN EHPAK; PROTEIN KINASE; PROTEIN P21; RAC PROTEIN; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

EID: 0037242401     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.00190     Document Type: Review
Times cited : (65)

References (46)
  • 1
    • 0032538973 scopus 로고    scopus 로고
    • PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia
    • Abo, A., Qu, J., Cammarano, M. S., Dan, C., Fritsch, A., Baud, V., Belisle, B. and Minden, A. (1998). PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia. EMBO J. 17, 6527-6540.
    • (1998) EMBO J. , vol.17 , pp. 6527-6540
    • Abo, A.1    Qu, J.2    Cammarano, M.S.3    Dan, C.4    Fritsch, A.5    Baud, V.6    Belisle, B.7    Minden, A.8
  • 2
    • 0028803237 scopus 로고
    • Myosin II is involved in capping and uroid formation in the human pathogen Entamoeba histolytica
    • Arhets, P., Gounon, P., Sansonetti, P. and Guillén, N. (1995). Myosin II is involved in capping and uroid formation in the human pathogen Entamoeba histolytica. Infect. Immun. 63, 4358-4367.
    • (1995) Infect. Immun. , vol.63 , pp. 4358-4367
    • Arhets, P.1    Gounon, P.2    Sansonetti, P.3    Guillén, N.4
  • 3
    • 0031867560 scopus 로고    scopus 로고
    • Virulence and functions of myosin II are inhibited by overexpression of light meromyosin in Entamoeba histolytica
    • Arhets, P., Olivo, J. C., Gounon, P., Sansonetti, P. and Guillén, N. (1998). Virulence and functions of myosin II are inhibited by overexpression of light meromyosin in Entamoeba histolytica. Mol. Biol. Cell 8, 1537-1547.
    • (1998) Mol. Biol. Cell , vol.8 , pp. 1537-1547
    • Arhets, P.1    Olivo, J.C.2    Gounon, P.3    Sansonetti, P.4    Guillén, N.5
  • 6
    • 0034678115 scopus 로고    scopus 로고
    • Regulation of the enzymatic and motor activities of myosin I
    • 1496
    • Barylko, B., Binns, D. D. and Albanesi, J. P. (2000). Regulation of the enzymatic and motor activities of myosin I. Biochim. Biophys. Acta. 1496, 23-35.
    • (2000) Biochim. Biophys. Acta , pp. 23-35
    • Barylko, B.1    Binns, D.D.2    Albanesi, J.P.3
  • 7
    • 0029911521 scopus 로고    scopus 로고
    • Interaction of the Nck adapter protein with p21-activated kinase (PAK1)
    • Bokoch, G. M., Wang, Y., Bohl, B. P., Sells, M. A., Quilliam, L. A. and Knaus, U. G. (1996). Interaction of the Nck adapter protein with p21-activated kinase (PAK1). J. Biol Chem. 271, 25746-25749.
    • (1996) J. Biol. Chem. , vol.271 , pp. 25746-25749
    • Bokoch, G.M.1    Wang, Y.2    Bohl, B.P.3    Sells, M.A.4    Quilliam, L.A.5    Knaus, U.G.6
  • 8
    • 0029911098 scopus 로고    scopus 로고
    • The catalytic domain of Acanthamoeba myosin I heavy chain kinase. II. Expression of active catalytic domain and sequence homology to p21-activated kinase (PAK)
    • Brzeska, H., Szczepanowska, J., Hoey, J. and Korn, E. D. (1996). The catalytic domain of Acanthamoeba myosin I heavy chain kinase. II. Expression of active catalytic domain and sequence homology to p21-activated kinase (PAK). J. Biol. Chem. 271, 27056-27062.
    • (1996) J. Biol. Chem. , vol.271 , pp. 27056-27062
    • Brzeska, H.1    Szczepanowska, J.2    Hoey, J.3    Korn, E.D.4
  • 9
    • 0028786020 scopus 로고
    • A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases
    • Burbelo, P. D., Dreschsel, D. and Hall, A. (1995). A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases. J. Biol. Chem. 270, 29071-29074.
    • (1995) J. Biol. Chem. , vol.270 , pp. 29071-29074
    • Burbelo, P.D.1    Dreschsel, D.2    Hall, A.3
  • 10
    • 0032438538 scopus 로고    scopus 로고
    • Phosphorylation of non-muscle myosin II regulatory light chain by p21-activated kinase (gamma-PAK)
    • Chew, T. L., Masaracchia, R. A., Goeckeler, Z. M. and Wysolmerski, R. B. (1998). Phosphorylation of non-muscle myosin II regulatory light chain by p21-activated kinase (gamma-PAK). J. Muscle Res. Cell Motil. 19, 839-854.
    • (1998) J. Muscle Res. Cell Motil. , vol.19 , pp. 839-854
    • Chew, T.L.1    Masaracchia, R.A.2    Goeckeler, Z.M.3    Wysolmerski, R.B.4
  • 11
    • 0033230933 scopus 로고    scopus 로고
    • PAKa, a putative PAK family member, is required for cytokinesis and the regulation of the cytoskeleton in Dictyostelium discoideum cells during chemotaxis
    • Chung, C. Y. and Firtel, R. A. (1999). PAKa, a putative PAK family member, is required for cytokinesis and the regulation of the cytoskeleton in Dictyostelium discoideum cells during chemotaxis. J. Cell Biol. 147, 559-576.
    • (1999) J. Cell Biol. , vol.147 , pp. 559-576
    • Chung, C.Y.1    Firtel, R.A.2
  • 12
    • 0035211279 scopus 로고    scopus 로고
    • Evidence for a molecular complex consisting of Fyb/SLAP, SLP-76, NcK, VASP and WASP that links the actin cytoskeleton to Fcγ receptor signalling during phagocytosis
    • Coppolino, M. G., Krause, M., Hagendorff, P., Monner, D. A., Trimble, W., Grinstein, S., Wehland, J. and Sechi, A. S. (2001). Evidence for a molecular complex consisting of Fyb/SLAP, SLP-76, NcK, VASP and WASP that links the actin cytoskeleton to Fcγ receptor signalling during phagocytosis. J. Cell Sci. 114, 4307-4318.
    • (2001) J. Cell Sci. , vol.114 , pp. 4307-4318
    • Coppolino, M.G.1    Krause, M.2    Hagendorff, P.3    Monner, D.A.4    Trimble, W.5    Grinstein, S.6    Wehland, J.7    Sechi, A.S.8
  • 13
    • 0035040153 scopus 로고    scopus 로고
    • Cell migration: GAPs between membrane traffic and the cytoskeleton
    • de Curtis, I. (2001). Cell migration: GAPs between membrane traffic and the cytoskeleton. EMBO Rep. 2, 277-281.
    • (2001) EMBO Rep. , vol.2 , pp. 277-281
    • de Curtis, I.1
  • 14
    • 0017846267 scopus 로고
    • A new medium for the axenic cultivation of Entamoeba histolytica and other Entamoeba
    • Diamond, L. S., Harlow, D. R. and Cunnick, C. C. (1978). A new medium for the axenic cultivation of Entamoeba histolytica and other Entamoeba. Trans. R. Soc. Trop. Med. Hyg. 72, 431-432.
    • (1978) Trans. R. Soc. Trop. Med. Hyg. , vol.72 , pp. 431-432
    • Diamond, L.S.1    Harlow, D.R.2    Cunnick, C.C.3
  • 16
    • 0029830139 scopus 로고    scopus 로고
    • The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1
    • Galisteo, M. L., Chernoff, J., Su, Y. C., Skolnik, E. Y. and Schlessinger, J. (1996). The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1. J. Biol Chem. 271, 20997-21000.
    • (1996) J. Biol. Chem. , vol.271 , pp. 20997-21000
    • Galisteo, M.L.1    Chernoff, J.2    Su, Y.C.3    Skolnik, E.Y.4    Schlessinger, J.5
  • 17
    • 0030771390 scopus 로고    scopus 로고
    • Unusual genome organisation in Entamoeba histolytica leads to two overlapping transcripts
    • Gangopadhyay, S., Sankar-Ray, S., Sinha, P. and Lohia, A. (1997). Unusual genome organisation in Entamoeba histolytica leads to two overlapping transcripts. Mol. Biochem. Parasitol. 89, 73-83.
    • (1997) Mol. Biochem. Parasitol. , vol.89 , pp. 73-83
    • Gangopadhyay, S.1    Sankar-Ray, S.2    Sinha, P.3    Lohia, A.4
  • 18
    • 0030003312 scopus 로고    scopus 로고
    • Role of signalling and cytoskeletal rearrangements in the pathogenesis of Entamoeba histolytica
    • Guillén, N. (1996). Role of signalling and cytoskeletal rearrangements in the pathogenesis of Entamoeba histolytica. Trends Microbiol. 4, 191-196.
    • (1996) Trends Microbiol. , vol.4 , pp. 191-196
    • Guillén, N.1
  • 19
    • 0031824045 scopus 로고    scopus 로고
    • The small GTP-binding protein RacG regulates uroid formation in the protozoan parasite Entamoeba histolytica
    • Guillén, N., Boquet, P. and Sansonetti, P. (1998). The small GTP-binding protein RacG regulates uroid formation in the protozoan parasite Entamoeba histolytica. J. Cell Sci. 111, 1729-1739.
    • (1998) J. Cell Sci. , vol.111 , pp. 1729-1739
    • Guillén, N.1    Boquet, P.2    Sansonetti, P.3
  • 20
    • 0032559362 scopus 로고    scopus 로고
    • Rho GTPases and the actin cytoskeleton
    • Hall, A. (1998). Rho GTPases and the actin cytoskeleton. Science 279, 509-514.
    • (1998) Science , vol.279 , pp. 509-514
    • Hall, A.1
  • 21
    • 0029050870 scopus 로고
    • Transfection and continuous expression of heterologous genes in the protozoan parasite Entamoeba histolytica
    • Hamann, L., Nickel, R. and Tannich, E. (1995). Transfection and continuous expression of heterologous genes in the protozoan parasite Entamoeba histolytica. Proc. Natl. Acad. Sci. USA 92, 8975-8979.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 8975-8979
    • Hamann, L.1    Nickel, R.2    Tannich, E.3
  • 24
    • 0032555504 scopus 로고    scopus 로고
    • Structural requirements for PAK activation by Rac GTPases
    • Knaus, U. G., Wang, Y., Reilly, A. M., Warnock, D. and Jackson, J. H. (1998). Structural requirements for PAK activation by Rac GTPases. J. Biol. Chem. 273, 21512-21518.
    • (1998) J. Biol. Chem. , vol.273 , pp. 21512-21518
    • Knaus, U.G.1    Wang, Y.2    Reilly, A.M.3    Warnock, D.4    Jackson, J.H.5
  • 25
    • 0033751057 scopus 로고    scopus 로고
    • Distribution of a potential p21-activated serine/threonine kinase (PAK) in Entamoeba histolytica
    • Labruyère, E., Galy, V., Sansonetti, P. and Guillen, N. (2000). Distribution of a potential p21-activated serine/threonine kinase (PAK) in Entamoeba histolytica. Arch. Med. Res. 31, S128-S130.
    • (2000) Arch. Med. Res. , vol.31
    • Labruyère, E.1    Galy, V.2    Sansonetti, P.3    Guillen, N.4
  • 26
    • 0029910216 scopus 로고    scopus 로고
    • Cloning and characterization of a Dictyostelium myosin I heavy chain kinase activated by Cdc42 and Rac
    • Lee, S. F., Egelhoff, T. T., Manesh, A. and Cote, G. P. (1996). Cloning and characterization of a Dictyostelium myosin I heavy chain kinase activated by Cdc42 and Rac. J. Biol. Chem. 271, 27044-27048.
    • (1996) J. Biol. Chem. , vol.271 , pp. 27044-27048
    • Lee, S.F.1    Egelhoff, T.T.2    Manesh, A.3    Cote, G.P.4
  • 27
    • 0027397652 scopus 로고
    • Molecular cloning of a rho family gene of Entamoeba histolytica
    • Lohia, A. and Samuelson, J. (1993). Molecular cloning of a rho family gene of Entamoeba histolytica. Mol. Biochem. Parasitol. 58, 177-180.
    • (1993) Mol. Biochem. Parasitol. , vol.58 , pp. 177-180
    • Lohia, A.1    Samuelson, J.2
  • 28
    • 0028078824 scopus 로고
    • A brain serine/threonine protein kinase activated by Cdc42 and Rac1
    • Manser, E., Leung, T., Salihuddin, H., Zhao, Z. S. and Lim, L. (1994). A brain serine/threonine protein kinase activated by Cdc42 and Rac1. Nature 367, 40-46.
    • (1994) Nature , vol.367 , pp. 40-46
    • Manser, E.1    Leung, T.2    Salihuddin, H.3    Zhao, Z.S.4    Lim, L.5
  • 29
    • 0031610579 scopus 로고    scopus 로고
    • PAK kinases are directly coupled to the PIX family of nucleotide exchange factors
    • Manser, E., Loo, T. H., Koh, C. G., Zhao, Z. S., Chen, X. Q., Tan, L., Tan, I., Leung, T. and Lim, L. (1998). PAK kinases are directly coupled to the PIX family of nucleotide exchange factors. Mol. Cell 1, 183-192.
    • (1998) Mol. Cell , vol.1 , pp. 183-192
    • Manser, E.1    Loo, T.H.2    Koh, C.G.3    Zhao, Z.S.4    Chen, X.Q.5    Tan, L.6    Tan, I.7    Leung, T.8    Lim, L.9
  • 30
    • 0033976108 scopus 로고    scopus 로고
    • Extracellular matrix-induced signaling in Entamoeba histolytica: Its role in invasiveness
    • Meza, I. (2000). Extracellular matrix-induced signaling in Entamoeba histolytica: its role in invasiveness. Parasitol. Today 16, 23-28.
    • (2000) Parasitol. Today , vol.16 , pp. 23-28
    • Meza, I.1
  • 31
    • 0030049170 scopus 로고    scopus 로고
    • Actin-based cell motility and cell locomotion
    • Mitchison, T. J. and Cramer, L. P. (1996). Actin-based cell motility and cell locomotion. Cell 84, 371-379.
    • (1996) Cell , vol.84 , pp. 371-379
    • Mitchison, T.J.1    Cramer, L.P.2
  • 32
    • 0033594123 scopus 로고    scopus 로고
    • Rho GTPases control polarity, protrusion, and adhesion during cell movement
    • Nobes, C. D. and Hall, A. (1999). Rho GTPases control polarity, protrusion, and adhesion during cell movement. J. Cell Biol. 144, 1235-1244.
    • (1999) J. Cell Biol. , vol.144 , pp. 1235-1244
    • Nobes, C.D.1    Hall, A.2
  • 33
    • 0031587921 scopus 로고    scopus 로고
    • Cloning of a SH3 domain-containing proline-rich protein, p85SPR, and its localization in focal adhesion
    • Oh, W. K., Yoo, J. C., Jo, D., Song, Y. H., Kim, M. G. and Park, D. (1997). Cloning of a SH3 domain-containing proline-rich protein, p85SPR, and its localization in focal adhesion. Biochem. Biophys. Res. Commun. 235, 794-798.
    • (1997) Biochem. Biophys. Res. Commun. , vol.235 , pp. 794-798
    • Oh, W.K.1    Yoo, J.C.2    Jo, D.3    Song, Y.H.4    Kim, M.G.5    Park, D.6
  • 36
    • 0027319218 scopus 로고
    • Molecular cloning of a rac family protein kinase and identification of a serine/threonine protein kinase gene family of Entamoeba histolytica
    • Que, X., Samuelson, J. and Reed, S. (1993). Molecular cloning of a rac family protein kinase and identification of a serine/threonine protein kinase gene family of Entamoeba histolytica. Mol. Biochem. Parasitol. 60, 161-170.
    • (1993) Mol. Biochem. Parasitol. , vol.60 , pp. 161-170
    • Que, X.1    Samuelson, J.2    Reed, S.3
  • 37
    • 0027215373 scopus 로고
    • Identification and characterization of a myosin heavy chain gene (mhcA) from the human parasitic pathogen Entamoeba histolytica
    • Raymond-Denise, A., Sansonetti, P. and Guillén, N. (1993). Identification and characterization of a myosin heavy chain gene (mhcA) from the human parasitic pathogen Entamoeba histolytica. Mol. Biochem. Parasitol. 59, 123-131.
    • (1993) Mol. Biochem. Parasitol. , vol.59 , pp. 123-131
    • Raymond-Denise, A.1    Sansonetti, P.2    Guillén, N.3
  • 39
    • 0033605738 scopus 로고    scopus 로고
    • Inhibition of myosin light chain kinase by p21-activated kinase
    • Sanders, L. C., Matsumura, F., Bokoch, G. M. and de Lanerolle, P. (1999). Inhibition of myosin light chain kinase by p21-activated kinase. Science 283, 2083-2085.
    • (1999) Science , vol.283 , pp. 2083-2085
    • Sanders, L.C.1    Matsumura, F.2    Bokoch, G.M.3    de Lanerolle, P.4
  • 40
    • 0033577902 scopus 로고    scopus 로고
    • p21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts
    • Sells, M. A., Boyd, J. T. and Chernoff, J. (1999). p21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts. J. Cell Biol. 145, 837-849.
    • (1999) J. Cell Biol. , vol.145 , pp. 837-849
    • Sells, M.A.1    Boyd, J.T.2    Chernoff, J.3
  • 41
    • 0030925571 scopus 로고    scopus 로고
    • Molecular characterization of myosin IB from the lower eukaryote Entamoeba histolytica, a human parasite
    • Vargas, M., Voigt, H., Sansonetti, P. and Guillén, N. (1997a). Molecular characterization of myosin IB from the lower eukaryote Entamoeba histolytica, a human parasite. Mol. Biochem. Parasitol. 86, 61-73.
    • (1997) Mol. Biochem. Parasitol. , vol.86 , pp. 61-73
    • Vargas, M.1    Voigt, H.2    Sansonetti, P.3    Guillén, N.4
  • 42
    • 0031031122 scopus 로고    scopus 로고
    • The tail domain of Entamoeba histolytica myosin IB bind F-actin
    • Vargas, M. A., Voigt, H., Sansonetti, P. and Guillén, N. (1997b). The tail domain of Entamoeba histolytica myosin IB bind F-actin. Arch. Med. Res. 28, 137-138.
    • (1997) Arch. Med. Res. , vol.28 , pp. 137-138
    • Vargas, M.A.1    Voigt, H.2    Sansonetti, P.3    Guillén, N.4
  • 43
    • 0033224440 scopus 로고    scopus 로고
    • New insights into the role of the cytoskeleton in phagocytosis of Entamoeba histolytica
    • Voigt, H. and Guillén, N. (1999). New insights into the role of the cytoskeleton in phagocytosis of Entamoeba histolytica. Cell. Microbiol. 1, 195-203.
    • (1999) Cell. Microbiol. , vol.1 , pp. 195-203
    • Voigt, H.1    Guillén, N.2
  • 44
    • 0032942542 scopus 로고    scopus 로고
    • Myosin IB is involved in phagocytosis of human erythrocytes by Entamoeba histolytica
    • Voigt, H., Olivo, J.-C., Sansonetti, P. and Guillén, N. (1999). Myosin IB is involved in phagocytosis of human erythrocytes by Entamoeba histolytica. J. Cell Sci. 112, 1191-1201.
    • (1999) J. Cell Sci. , vol.112 , pp. 1191-1201
    • Voigt, H.1    Olivo, J.-C.2    Sansonetti, P.3    Guillén, N.4
  • 46
    • 0036826342 scopus 로고    scopus 로고
    • Segmentation and tracking of migration cells in videomicroscopy with parametric active contours: A tool for cell-based drug testing
    • (in press)
    • Zimmer, C., Labruyère, E., Meas-Yedid, V., Guillén, N. and Olivo-Marin, J.-C. (2002). Segmentation and tracking of migration cells in videomicroscopy with parametric active contours: a tool for cell-based drug testing. IEEE. Trans. Medical Imaging (in press).
    • (2002) IEEE. Trans. Medical Imaging
    • Zimmer, C.1    Labruyère, E.2    Meas-Yedid, V.3    Guillén, N.4    Olivo-Marin, J.-C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.