Actin cytoskeleton organization regulated by the PAK family of protein kinases

Current Biology

Volumn 8, Issue 17, 1998, Pages 967-970

  Eby, Jennifer J ^a   Holly, Stephen P ^b   Van Drogen, Frank ^c   Grishin, Anatoly V ^b   Peter, Matthias ^c   Drubin, David G ^a   Blumer, Kendall J ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c SWISS INST FOR EXP CANCER RESEARCH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

SACCHAROMYCES CEREVISIAE; SACCHAROMYCETALES;

EID: 0032572702     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0960-9822(98)00398-4     Document Type: Article

References (26)

1. Van Aelst L, D'Souza-Schorey C: Rho GTPases and signaling networks. Genes Dev 1997, 11:2295-2322.
2. Hall A: Rho GTPases and the actin cytoskeleton. Science 1998, 279:509-514.
3. Joneson T, McDonough M, Bar-Sagi D, Van Aelst L: RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase. Science 1996, 274:1374-1376.
4. Lamarche N, Tapon N, Stowers L, Burbelo PD, Aspenstrom P, Bridges T, et al.: Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade. Cell 1996, 87:519-529.
5. Westwick JK, Westwick JK, Lambert QT, Clark GJ, Symons M, Van Aelst L, et al:. Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways. Mol Cell Biol 1997, 17:1324-1335.
6. Cvrckova F, De Virgilio C, Manser E, Pringle JR, Nasmyth K: Ste20-like protein kinases are required for normal localization of cell growth and for cytokinesis in budding yeast. Genes Dev 1995, 9:1817-1830.
7. Peter M, Neiman AM, Park HO, van Lohuizen M, Herskowitz I: Functional analysis of the interaction between the small GTP binding protein Cdc42 and the Ste20 protein kinase in yeast. EMBO J 1996, 15:7046-7059.
8. Leberer E, Wu C, Leeuw T, Fourest-Lieuvin A, Segall JE, Thomas DY: Functional characterization of the Cdc42p binding domain of yeast Ste20p protein kinase. EMBO J 1997, 16:83-97.
9. Sprague GFJ, Thorner JW: Chapter 12 in The Molecular and Cellular Biology of the Yeast Saccharomyces. Edited by Jones EW, Pringle JR, Broach JR. New York: Cold Spring Harbor Laboratory Press; 1992: 657-744.
10. Lew DJ, Reed SI: Morphogenesis in the yeast cell cycle: regulation by Cdc28 and cyclins. J Cell Biol 1993, 120:1305-1320.
11. Buehrer BM, Errede B: Coordination of the mating and cell integrity mitogen-activated protein kinase pathways in Saccharomyces cerevisiae. Mol Cell Biol 1997, 17:6517-6525.
12. Li R, Zheng Y, Drubin DG: Regulation of cortical actin cytoskeleton assembly during polarized cell growth in budding yeast. J Cell Biol 1995, 128:599-615.
13. Chen GC, Kim YJ, Chan CSM: The Cdc42 GTPase-associated proteins Gic1 and Gic2 are required for polarized cell growth In Saccharomyces cerevisiae. Genes Dev 1997, 11:2958-2971.
14. Brown JL, Jaquenoud M, Gulli MP, Chant J, Peter M: Novel Cdc42-binding proteins Gic1 and Gic2 control cell polarity in yeast. Genes Dev 1997, 11:2972-2982.
15. Evangelista M, Blundell K, Longtine MS, Chow CJ, Adames N, Pringle JR, et al:. Bni1p, a yeast formin linking Cdc42p and the actin cytoskeleton during polarized morphogenesis. Science 1997, 276:118-122.
16. Imamura H, Tanaka K, Hihara T, Umikawa M, Kamei T, Takahashi K, et al:. Bni1p and Bnr1p: downstream targets of the Rho family small G-proteins which interact with profilin and regulate actin cytoskeleton in Saccharomyces cerevisiae. EMBO J 1997, 16:2745-2755.
17. Leeuw T, Fourest-Lieuvin A, Wu C, Chenevert J, Clark K, Whiteway M, et al:. Pheromone response in yeast: association of Bem1p with proteins of the MAP kinase cascade and actin. Science 1995, 270:1210-1213.
18. Harden N, Lee J, Loh HY, Ong YM, Tan I, Leung T, et al:. A Drosophila homolog of the Rac- and Cdc42-activated serine/threonine kinase PAK is a potential focal adhesion and focal complex protein that colocalizes with dynamic actin structures. Mol Cell Biol 1996, 16:1896-1908.
19. Manser E, Huang HY, Loo TH, Chen XQ, Dong JM, Leung T, Lim L: Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes. Mol Cell Biol 1997, 7:1129-1143.
20. Dharmawardhane S, Sanders LC, Martin SS, Daniels RH, Bokoch GM: Localization of p21-activated kinase 1 (PAK1) to pinocytic vesicles and cortical actin structures in stimulated cells. J Cell Biol 1997, 138:1265-1278.
21. Sells MA, Knaus UG, Bagrodia S, Ambrose DM, Bokoch GM, Chernoff J: Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells. Curr Biol 1997, 7:202-210.
22. Lee SF, Egelhoff TT, Mahasneh A, Cote GP: Cloning and characterization of a Dictyostelium myosin I heavy chain kinase activated by Cdc42 and Rac. J Biol Chem 1996, 271:27044-17048.
23. Wu C, Lee SF, Furmaniak-Kazmierczak E, Cote GP, Thomas DY, Leberer E: Activation of myosin-I by members of the Ste20p protein kinase family. J Biol Chem 1996, 271:31787-31790.
24. Brzeska H, Knaus UG, Wang ZY, Bokoch GM, Korn ED: p21-activated kinase has substrate specificity similar to Acanthamoeba myosin I heavy chain kinase and activates Acanthamoeba myosin I. Proc Natl Acad Sci USA 1997, 94:1092-1095.
25. Zhao Z-S, Manser E, Chen X-Q, Chong C, Leung T, Lim L: A conserved negative regulatory region of αPAK: inhibition of PAK kinases reveals their morphological roles downstream of Cdc42 and Rac1. Mol Cell Biol 1998, 18:2153-2163.
26. Symons M, Derry JM, Karlak B, Jiang S, Lemahieu V, Mccormick F, et al:. Wiskott-Aldrich syndrome protein, a novel effector for the GTPase Cdc42hs, is implicated in actin polymerization. Cell 1996, 84:723-734.