Acute hypertension after nitric oxide synthase inhibition is mediated primarily by increased endothelin vasoconstriction

Journal of Hypertension

Volumn 14, Issue 8, 1996, Pages 975-981

  Banting, James D ^a   Friberg, Peter ^b   Adams, Michael A ^a  

^a QUEEN S UNIVERSITY   (Canada)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Endothelin 1; Hypertension; N( ) nitro L arginine methyl ester; Nitric oxide; Nitric oxide synthase

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; ARGININE METHYL ESTER; ENALAPRIL; ENDOTHELIN; LOSARTAN; N ACETYL 10,11 DIHYDRO 5H DIBENZO[A,D]CYCLOHEPTEN 5 YLGLYCYLLEUCYLASPARTYLISOLEUCYLISOLEUCYLTRYPTOPHAN; NITRIC OXIDE SYNTHASE; PRAZOSIN; VASOPRESSIN; VASOPRESSIN V1 RECEPTOR; VASOPRESSIN V2 RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; ENZYME INHIBITION; HYPERTENSION; MALE; NONHUMAN; PRESSOR RESPONSE; PRIORITY JOURNAL; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; VASOCONSTRICTION;

EID: 0029792208     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004872-199608000-00007     Document Type: Article

References (27)

1. Johnson RA, Freeman RH: Sustained hypertension in the rat induced by chronic blockade of nitric oxide production. Am J Hypertens 1992, 5:919-922.
2. Tolins JP, Shulz PJ, Raij L: Role of endothelium-derived relaxing factor in regulation of vascular tone and remodeling. Update on humoral regulation of vascular tone. Hypertension 1991, 17:909-916.
3. Bank N, Aynedjian HS, Khan GA: Mechanism of vasoconstriction induced by chronic inhibition of nitric oxide in rats. Hypertension 1994, 24:322-328.
4. Sigmon DH, Beierwaltes W: Nitric oxide influences blood flow distribution in renovascular hypertension. Hypertension 1994, 24 (suppl I):I34-I39
5. Pollock DM, Polakowski JS, Divish BJ, Opgenorth TJ: Angiotensin blockade reverses hypertension during long-term nitric oxide synthase inhibition. Hypertension 1993, 21:660-666.
6. MacLean MR, Graham J, McGrath JC: Endogenous nitric oxide modulates vasopressor responses, but not depressor responses, to spinal sympathetic nerve stimulation in pithed rats. J Cardiovasc Pharmacol 1994, 23:319-325.
7. de Nicola LD, Blantz RC, Gabbit FB: Nitric oxide and angiotensin II glomerular and tubular interaction in the rat J Clin Invest 1992, 89:1248-1256.
8. G-nitro-L-arginine as effected by blockade of pressor mechanisms mediated by the sympathetic nervous system, angiotensin, prostanoids and vasopressin. J Pharmacol Exp Ther 1992, 261:240-245.
9. Arnal JF, Amrani AIE, Chatellier G, Ménard J, Michel JB: Cardiac weight in hypertension induced by nitric oxide synthase blockade. Hypertension 1993, 22:380-387.
10. Moncada A, Palmer RMJ, Higgs EA: Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991, 43:109-142.
11. 1-adrenergic receptor-induced trophic responses in the vasculature. Hypertension 1992, 20:809-815.
12. Wellings RP, Warner TD, Thiemermann C, Cristol JP, Corder R, Vane JR: Vasoconstriction in the rat kidney induced by endothelin-1 is blocked by PD 145 065. J Cardiovasc Pharmacol 1993, 22 (suppl 8):s103-s106.
13. McMurdo L, Corder R, Thiermermann C, Van JR: Incomplete inhibition of the presser effects of endothelin-1 and related peptides in the anesthetized rat with BQ-123 provides evidence for more than one vasoconstrictor receptor. J Pharmacol 1993, 108:557-561.
14. Li J-S, Schiffrin EL: Effect of chronic treatment of adult spontaneously hypertensive rats with an endothelin receptor antagonist. Hypertension 1995, 25 (part 1):495-500.
15. Schiffrin EL, Larivière , Li J-S, Sventek P, Touyz RM: Deoxycorticosterone acetate plus salt induces overexpression of vascular endothelin-1 and severe vascular hypertrophy in spontaneously hypertensive rats. Hypertension 1995, 25 (part 2):769-773.
16. Takeda Y, Miyamori I, Wu P, Yoneda T, Furukawa K, Takeda R: Effects of an endothelin receptor antagonist in rats with cyclosporin-induced hypertension. Hypertension 1995, 26 (part 1):932-936.
17. Richard V, Hogie M, Clozel M, Loffler BM, Thuillez C: In vivo evidence of an endothelin-induced vasopressor tone after inhibition of nitric oxide synthesis in rats. Circulation 1995, 91:771-775.
18. Hirata Y, Hayakawa H, Matsuoka H, Sugimoto T, Kangawa K, Matsuo H: Mechanisms of the natriuretic effects of neutral endopeptidase inhibition in Dahl salt-sensitive and salt-resistant rats. J Cardiovasc Pharmacol 1994, 23:283-290.
19. Gilbert BW: ACE inhibitors and regression of left ventricular hypertrophy. Clin Cardiol 1992, 15:711-714.
20. Conte G, Romano G, Sepe V, de Nicola L, Sabbatini M, Russo D, et al.: Role of inhibition of atrial natriuretic factor release in the down-regulation of salt excretion. Kidney Int 1992, 42:673-680.
21. Dietz JR, Vesely DL, Nazian SJ: Effect of changes in sodium intake on atrial natriuretic factor (ANF) and peptides derived from the N terminus of the ANF prohormone in the rat Proc Soc Exp Biol Med 1992, 200:44-48.
22. Boulanger C, Luscher TF: Release of endothelin from the porcine aorta: inhibition by endothelium-derived nitric oxide. J Clin Invest 1991, 85:587-590.
23. Kourembanas S, McQuillan LP, Leung GK, Faller DV: Nitric oxide regulates the expression of vasoconstrictors and growth factors by vascular endothelium under normoxia and hypoxia. J Clin Invest 1993, 92:99-104.
24. G-nitro-L-arginine in conscious sheep. J Cardiovasc Pharmacol 1994, 24:144-150.
25. Luscher TF, Seo BG, Buhler FR: Potential role of endothelin in hypertension: controversy on endothelin in hypertension. Hypertension 1993, 26:752-757.
26. Wanger OF, Christ G, Wojta J, Vierhapper H, Parzer, Nowonty PJ, et al.: Polar secretion of endothelin-1 by cultural endothelial cells. J Biol Chem 1992, 267:16066-16088.
27. G-nitro-L-arginine methyl ester. Br J Pharmacol 1990, 101:632-639.