Crystal structures of cyanide complexes of P450cam and the oxygenase domain of inducible nitric oxide synthase - Structural models of the short-lived oxygen complexes

Archives of Biochemistry and Biophysics

Volumn 409, Issue 1, 2003, Pages 25-31

  Fedorov, Roman ^a   Ghosh, Dipak K ^b   Schlichting, Ilme ^a,c  

^a MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

^b DUKE UNIVERSITY   (United States)

^c MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

Author keywords

Crystal structure; CYP; Hemoprotein; Monooxygenase; Nitric oxide synthase; Oxygen; Oxygen analogue; Reaction mechanism; X ray radiolysis

Indexed keywords

ARGININE; ASPARAGINE; CAMPHOR; CARBONYL DERIVATIVE; CYANIDE; CYTOCHROME P450; NITRIC OXIDE SYNTHASE; NITROGEN; OXYGEN; OXYGENASE; PROTON; WATER;

AMINO ACID ANALYSIS; ARTICLE; BINDING AFFINITY; CHEMICAL BOND; CHEMICAL INTERACTION; COMPLEX FORMATION; CONFORMATION; CRYSTAL STRUCTURE; ENZYME ANALYSIS; ENZYME MECHANISM; HYDROXYLATION; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

ANIMALS; ARGININE; ASPARTIC ACID; CAMPHOR; CRYSTALLOGRAPHY, X-RAY; CYANIDES; CYTOCHROME P-450 ENZYME SYSTEM; HYDROXYLATION; MICE; MODELS, MOLECULAR; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; OXYGEN; OXYGENASES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PROTONS;

DRYOBALANOPS;

EID: 0037229513     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-9861(02)00555-6     Document Type: Article

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