Alterations of the blood-brain barrier and glial cells in white-matter lesions in cerebrovascular and Alzheimer's disease patients

Stroke

Volumn 27, Issue 11, 1996, Pages 2069-2074

  Tomimoto, Hidekazu ^a   Akiguchi, Ichiro ^a   Suenaga, Toshihiko ^a   Nishimura, Masaki ^a   Wakita, Hideaki ^a   Nakamura, Shinichi ^a   Kimura, Jun ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Alzheimer's disease; astrocytes; Binswanger's disease; blood brain barrier; white matter

Indexed keywords

AMYLOID PRECURSOR PROTEIN; FIBRINOGEN; GLIAL FIBRILLARY ACIDIC PROTEIN; HLA DR ANTIGEN; IMMUNOGLOBULIN; PLASMA PROTEIN;

AGED; ALZHEIMER DISEASE; ARTICLE; BLOOD BRAIN BARRIER; CEREBROVASCULAR DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GLIA CELL; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; PRIORITY JOURNAL; WHITE MATTER;

EID: 0029804231     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.27.11.2069     Document Type: Article

References (53)

1. Hachinski VC, Potter P, Merskey H. Leuko-araiosis. Arch Neurol. 1987;44:21-23.
2. Marshall VG, Bradley WG Jr, Marshall CE, Bhoopat T, Rhodes RH. Deep white matter infarction: correlation of MR imaging and histopathologic findings. Radiology. 1988;167:517-522.
3. Yamanouchi H, Sugiura S. Tomonaga M. Decrease in nerve fibers in cerebral white matter in progressive subcortical vascular encephalopathy of Binswanger type: an electron microscopic study. J Neurol. 1989;236:382-387.
4. Grafton ST, Sumi SM, Stimac GK, Alvord EC Jr, Shaw CM, Nochlin D. Comparison of postmortem magnetic resonance imaging and neuropathologic findings in the cerebral white matter. Arch Neurol. 1991; 48:293-298.
5. Stewart PA, Hayakawa K, Akers MA, Vinters HV. Cognitive and neurologic findings in demented patients with diffuse white matter lucencies on computed tomographic scan (leuko-araiosis). Arch Neurol. 1987;44:36-39.
6. Parnetti L, Mari D, Mecocci P, Senin U. Pathogenetic mechanisms in vascular dementia. Int J Clin Lab Res. 1994;24:15-22.
7. Wallin A, Blennow K. Heterogeneity of vascular dementia: mechanisms and subgroups. J Geriatr Psychiatry Neurol. 1993;6:177-188.
8. Brun A, Englund E. A white matter disorder in dementia of the Alzheimer type: a patho-anatomical study. Ann Neurol. 1986;19: 253-262.
9. Caplan LR, Schoene WC. Clinical features of subcortical arteriosclerotic encephalopathy (Binswanger's disease). Neurology. 1978;28: 1206-1215.
10. Feigin I, Popoff N. Neuropathological changes late in cerebral edema: the relationship to trauma, hypertensive disease and Binswanger's encephalopathy. J Neuropathol Exp Neurol. 1963;22: 500-511.
11. Gay D, Esiri M. Blood-brain barrier damage in acute multiple sclerosis plaques: an immunocytological study. Brain. 1991; 114:557-572.
12. Kwon EE, Prineas JW. Blood-brain barrier abnormalities in long-standing multiple sclerosis lesions: an immunohistochemical study. J Neuropathol Exp Neurol. 1994;53:625-636.
13. Petito CK, Cash KS. Blood-brain barrier abnormalities in the acquired immunodeficiency syndrome: immunohistochemical localization of serum proteins in postmortem brain. Ann Neurol. 1992;32: 658-666.
14. Wisniewski HM, Kozlowski PB. Evidence for blood-brain barrier changes in senile dementia of the Alzheimer type (SDAT). Ann N Y Acad Sci. 1982;396:119-129.
15. Sparrow JR. Immunohistochemical study of the blood-brain barrier: production of artifact. J Histochem Cytochem. 1979;28:570-572.
16. Mori S, Sternberger NH, Herman MM, Sternberger LA. Leakage and neuronal uptake of serum protein in aged and Alzheimer brains: a postmortem phenomenon with antemortem etiology. Lab Invest. 1991;64:345-351.
17. Fabian RH, Petroff G. Intraneuronal IgG in the central nervous system: uptake by retrograde axonal transport. Neurology. 1987;37: 1780-1784.
18. Liu HM, Atack JR, Rapoport SI. Immunohistochemical localization of intracellular plasma proteins in the central nervous system. Acta Neuropathol (Berl). 1989;78:16-21.
19. Fishman PS, Savitt JM. Selective localization by neuroglia of immunoglobulin G in normal mice. J Neuropathol Exp Neurol. 1989; 48:212-220.
20. Mirra SS, Heyman A, McKeel D, Sumi SM, Crain BJ, Brownlee LM, Vogel FS, Hughes JP, van Belle G, Berg L, and participating CERAD neuropathologists. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD), II: standardization of the neuropathologic assessment of Alzheimer's disease. Neurology. 1991;41: 479-486.
21. Englund E, Brun A. White matter changes in dementia of Alzheimer's type: the difference in vulnerability between cell compartments. Histopathology. 1990;16:433-439.
22. Gentleman SM, Nash MJ, Sweeting CJ, Graham DI, Roberts GW. Beta-amyloid precursor protein (beta APP) as a marker for axonal injury after head injury. Neurosci Lett. 1993;160:139-144.
23. Suenaga T, Ohnishi K, Nishimura M, Nakamura S, Akiguchi I, Kimura J. Bundles of amyloid precursor protein-immunoreactive axons in human cerebrovascular white matter lesions. Acta Neuropathol (Berl). 1994;87:450-455.
24. Tomimoto H, Akiguchi I, Wakita H, Nakamura S, Kimura J. Ultrastructural localization of amyloid protein precursor in the normal and postischemic gerbil brain. Brain Res. 1995;672:187-195.
25. Tomimoto H, Akiguchi I, Suenaga T, Wakita H, Nakamura S, Kimura J. Immunohistochemical study of apolipoprotein E in human cerebrovascular white matter lesions. Acta Neuropathol (Berl). 1995; 90:608-614.
26. Suzuki M, Iwasaki Y, Umezawa K, Motohashi O, Shida N. Distribution of extravasated protein after cryoinjury in neonatal and adult rat brains. Acta Neuropathol (Berl). 1995;89:532-536.
27. Bernstein JJ, Goldberg WJ. Injury-related spinal cord astrocytes are immunoglobulin-positive (IgM and/or IgG) at different time periods in the regenerative process. Brain Res. 1987;426:112-118.
28. Ma K-C, Lundberg PO, Lilja A, Olsson Y. Binswanger's disease in the absence of chronic arterial hypertension. Acta Neuropathol (Berl). 1992;83:434-439.
29. Leys D. Pruvo JP, Parent M, Vermersch P, Soetaert G, Steinling M, Delacourte A, Défossez A, Rapoport A, Clarisse J, Petit H. Could wallerian degeneration contribute to 'leuko-araiosis' in subjects free of any vascular disorder? J Neurol Neurosurg Phychiatry. 1991;54: 46-50.
30. Alafuzoff I, Adolfsson R, Bucht G, Winblad B. Albumin and immunoglobulin in plasma and cerebrospinal fluid, and blood cerebrospinal fluid barrier function in patients with dementia of Alzheimer type and multi-infarct dementia. J Neurol Sci. 1983;60:465-472.
31. Elovaara I, Palo J, Erkinjuntti T, Sulkava R. Serum cerebrospinal fluid proteins and the blood-brain barrier in Alzheimer's disease and multi-infarct dementia. Eur Neurol. 1987;26:229-234.
32. Leonardi A, Gandolfo C, Caponnette C, Arata L, Vecchia R. The integrity of the blood-brain barrier in Alzheimer's type and multiintarct dementia evaluated by the study of albumin and IgG in serum and cerebrospinal fluid. J Neurol Sci. 1985;67:253-261.
33. Mecocci P, Parnetti L, Reboldi GP, Santucci C, Gaiti A, Ferri C, Gemini I, Romagnoli M, Cadini D, Senin U. Blood-brain barrier in a geriatric population: barrier function in degenerative and vascular dementias. Acta Neurol Scand. 1991;84:210-213.
34. Blennow K, Wallin A, Fredman P, Karlsson I, Gottfries CG. Svennerholm L. Blood-brain barrier disturbance in patients with Alzheitner's disease is related to vascular factors. Acta Neurol Scand. 1990; 81:323-326.
35. Tohgi H, Abe T, Takahashi S, Kikuchi T. The urate and xanthine concentrations in the cerebrospinal fluid in patients with vascular dementia of the Binswanger's type, Alzheimer type dementia, and Parkinson's disease. J Neural Transm Park Dis Dement Sect. 1993; 6:119-126.
36. Alafuzoff I, Adolfsson R, Grundke-Iqbal I, Winblad B. Blood-brain barrier in Alzheimer dementia and in non-demented elderly: an immunocytochemical study. Acta Neuropathol (Berl). 1987; 73:160-166.
37. Rozemuller JM, Eikelenboom P, Kamphorst W, Stam FC. Lack of evidence for dysfunction of the blood-brain barrier in Alzheimer's disease: an immunohistochemical study. Neurobiol Aging. 1988;9: 383-391.
38. Fischer VW, Siddiqi A, Yusufaly Y. Altered angioarchitecture in selected areas of brains with Alzheimer's disease. Acta Neuropathol (Berl). 1990;79:672-679.
39. Stewart PA, Hayakawa K, Akers MA, Vinters HV. A morphometric study of the blood-brain barrier in Alzheimer's disease. Lab Invest. 1992;67:734-742.
40. Yanagihara T, Cumings JN. Lipid metabolism in cerebral edema associated with human brain tumor. Arch Neurol. 1968;19:241-247.
41. Silberberg DH, Manning MC, Schreiber AD. Tissue culture demyelination by normal human serum. Ann Neurol. 1984;15:575-580.
42. Akiyama H, Tooyama I, Kondo H, Ikeda K, Kimura H, McGeer EG, McGeer PL. Early response of brain resident microglia to kainic acid-induced hippocampal lesions. Brain Res. 1994;635:257-268.
43. Tomimoto H, Akiguchi I, Akiyama H, Kimura J, Yanagihara T. T cell infiltration and expression of MHC class II antigen by macrophage/microglia in a heterogeneous group of leukoencephalopathy. Am J Pathol. 1993;143:579-586.
44. Wakita H, Tomimoto H, Akiguchi I, Kimura J. Glial activation and white matter changes in the rat brain induced by chronic cerebral hypoperfusion: an immunohistochemical study. Acta Neuropathol (Berl). 1994;87:484-492.
45. McGeer PL, Itagaki S, Boyes BE, McGeer EG. Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains. Neurology. 1988;38:1285-1291.
46. Lee GJ. The possible contribution of microglia and macrophages to delayed neuronal death after ischemia. J Neurol Sci. 1993;114: 119-122.
47. Yamanouchi H. Loss of white matter oligodendrocytes and astrocytes in progressive subcortical vascular encephalopathy of Binswanger type. Acta Neurol Scand. 1991;83:301-305.
48. Englund E, Brun A. White matter changes in dementia of Alzheimer's type: the difference in vulnerability between cell compartments. Histopathology. 1990;16:4.33-439.
49. Duchen LW. General pathology of neurons and neuroglia. In: Adams JH, Duchen LW, eds. Greenfield's Neuropathology. London, England: Arnold; 1992:1-68.
50. Tang JP, Xu ZQ, Douglas FL, Rakhit A, Melethil S. Increased blood-brain barrier permeability of amino acids in chronic hypertension. Life Sci. 1993;53:PL417-PL420.
51. Meuller SM, Luft FC. The blood brain barrier in renovascular hypertension. Stroke. 1982;13:229-234.
52. Spangler KM, Chulla VR, Moody DM, Bell MA. Arteriolar tortuosity of the white matter in aging and hypertension. J Neuropathol Exp Neurol. 1994;53:22-26.
53. Moody DM, Brown WR, Challa VR, Anderson RL. Periventricular venous collagenosis: association with leukoaraiosis. Radiology. 1995;194:469-476.