Acridinecarboxamide topoisomerase poisons: Structural and kinetic studies of the DNA complexes of 5-substituted 9-amino-(N-(2-dimethylamino)ethyl)acridine-4-carboxamides

Molecular Pharmacology

Volumn 58, Issue 3, 2000, Pages 649-658

  Adams, Adrienne ^a   Guss, J Mitchell ^a   Collyer, Charles A ^a   Denny, William A ^b   Prakash, Arungundrum S ^c   Wakelin, Laurence P G ^d  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

^c University of Queensland and Queensland Alliance for Environmental Health Sciences   (Australia)

^d UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

4 ACRIDINECARBOXAMIDE DERIVATIVE; ACRIDINE DERIVATIVE; CYTOTOXIC AGENT; DNA TOPOISOMERASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; BINDING SITE; CYTOTOXICITY; DNA BINDING; DRUG STRUCTURE; HYDROGEN BOND; MOLECULAR STABILITY; PRIORITY JOURNAL; SPECTROPHOTOMETRY; X RAY CRYSTALLOGRAPHY;

EID: 0033859496     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.58.3.649     Document Type: Article

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