Structural origins of the functional divergence of human insulin-like growth factor-I and insulin

Biochemistry

Volumn 41, Issue 30, 2002, Pages 9389-9397

  Brzozowski, Andrzej M ^a   Dodson, Eleanor J ^a   Dodson, Guy G ^a   Murshudov, Garib N ^a   Verma, Chandra ^a   Turkenburg, Johan P ^a   De Bree, Frederik M ^a,b   Dauter, Zbigniew ^a,c  

^a UNIVERSITY OF YORK   (United Kingdom)

^b NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

^c BROOKHAVEN NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING MODES;

CELLS; CHEMICAL BONDS; CONFORMATIONS; INSULIN; POLYPEPTIDES; PROTEINS;

BIOCHEMISTRY;

INSULIN; PROINSULIN; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN C;

ARTICLE; BETA CHAIN; CARBOXY TERMINAL SEQUENCE; CHEMICAL BOND; CONFORMATION; CRYSTALLIZATION; HORMONAL REGULATION; HORMONE PROTEIN COMPLEX; HORMONE RELEASE; HORMONE STRUCTURE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DOMAIN; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; HUMANS; HYDROGEN BONDING; INSULIN; INSULIN-LIKE GROWTH FACTOR I; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0037199459     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi020084j     Document Type: Article

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