Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 Pro → Asp insulin analogues

Biochemistry

Volumn 37, Issue 33, 1998, Pages 11516-11523

  Whittingham, Jean L ^a   Edwards, David J ^a,b   Antson, Alfred A ^a   Clarkson, Judy M ^a   Dodson, G Guy ^a  

^a UNIVERSITY OF YORK   (United Kingdom)

^b ACCELRYS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; INSULIN; PROLINE;

ALPHA HELIX; ANTIMICROBIAL ACTIVITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CRYSTALLIZATION; CRYSTALLOGRAPHY; DISULFIDE BOND; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN PROTEIN INTERACTION;

ASPARTIC ACID; BINDING SITES; CRESOLS; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; INSULIN; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; PHENOL; PROLINE; PROTEIN STRUCTURE, SECONDARY;

EID: 0032544188     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi980807s     Document Type: Article

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