The insulin-like growth factor (IGF) binding protein 1 binding epitope on IGF-I probed by heteronuclear NMR spectroscopy and mutational analysis

Journal of Biological Chemistry

Volumn 273, Issue 38, 1998, Pages 24701-24707

  Jansson, Magnus ^a,b   Andersson, Gunilla ^a   Uhlén, Mathias ^b   Nilsson, Björn ^a   Kördel, Johan ^a  

^a PFIZER INC   (United States)

^b ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

SOMATOMEDIN BINDING PROTEIN 1; SOMATOMEDIN C;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CIS TRANS ISOMERISM; CONFORMATIONAL TRANSITION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; BINDING SITES; BIOSENSING TECHNIQUES; CLONING, MOLECULAR; DNA MUTATIONAL ANALYSIS; DNA PRIMERS; EPITOPES; ESCHERICHIA COLI; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1; INSULIN-LIKE GROWTH FACTOR I; KINETICS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; POINT MUTATION; POLYMERASE CHAIN REACTION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; VARIATION (GENETICS);

EID: 0032544407     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.38.24701     Document Type: Article

References (50)

1. Bach, L. A., Hsieh, S., Sakano, K., Fujiwara, H., Perdue, J. F., and Rechler, M. M. (1993) J. Biol. Chem. 268, 9246-9254
2. Hober, S., Hansson, A., Uhlén, M., and Nilsson, B. (1994) Biochemistry 33, 6758-6761
3. Mohan, S., Nakao, Y., Honda, Y., Landale, E., Leser, U., Dony, C., Lang, K., and Baylink, D. J. (1995) J. Biol. Chem. 270, 20424-20431
4. Swisshelm, K., Ryan, K., Tsuchiya, K., and Sager, R. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 4472-4476
5. Cooke, R. M., Harvey, T. S., and Campbell, I. D. (1991) Biochemistry 30, 5484-5491
6. Hua, Q. X., Narhi, L., Jia, W. H., Arakawa, T., Rosenfeld, R., Hawkins, N., Miller, J. A., and Weiss, M. A. (1996) J. Mol. Biol. 259, 297-313
7. Kobayashi, Y., Nishimura, S., Ohkubo, T., Kyogoku, Y., Sato, A., Koyama, S., Kobayashi, M., and Yasuda, T. (1991) in Peptides 1990 (Giralt, E., and Andreu, D., eds) pp. 565-567, ESCOM, Leiden, The Neterlands
8. Sato, A., Nishimura, S., Ohkubo, T., Kyogoku, Y., Koyama, S., Kobayashi, M., Yasuda, T., and Kobayashi, Y. (1992) J. Biochem. (Tokyo) 111, 529-536
9. Sato, A., Nishimura, S., Ohkubo, T., Kyogoku, Y., Koyama, S., Kobayashi, M., Yasuda, T., and Kobayashi, Y. (1993) Int. J. Pept. Protein Res. 41, 433-440
10. Terasawa, H., Kohda, D., Hatanaka, H., Nagata, K., Higashihashi, N., Fujiwara, H., Sakano, K., and Inagaki, F. (1994) EMBO J. 13, 5590-5597
11. Torres, A. M., Forbes, B. E., Aplin, S. E., Wallace, J. C., Francis, G. L., and Norton, R. S. (1995) J. Mol. Biol. 248, 385-401
12. Hua, Q. X., Shoelson, S. E., Inouye, K., and Weiss, M. A. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 582-586
13. Olsen, H. B., Ludvigsen, S., and Kaarsholm, N. C. (1996) Biochemistry 35, 8836-8845
14. Ballard, F. J., Francis, G. L., Ross, M., Bagley, C. J., May, B., and Wallace, J. C. (1987) Biochem. Biophys. Res. Commun. 149, 398-404
15. Bagley, C. J., May, B. L., Szabo, L., McNamara, P. J., Ross, M., Francis, G. L., Ballard, F. J., and Wallace, J. C. (1989) Biochem. J. 259, 665-671
16. Clemmons, D. R., Dehoff, M. L., Busby, W. H., Bayne, M. L., and Cascieri, M. A. (1992) Endocrinology 131, 890-895
17. Clackson, T., and Wells, J. A. (1995) Science 267, 383-386
18. Nilsson, B., Moka, T., Jansson, B., Abrahmsén, L., Elmblad, A., Holmgren, E., Henrichson, C., Jones, T. A., and Uhlén, M. (1987) Protein Eng. 1, 107-113
19. Jansson, M., Li, Y. C., Jendeberg, L., Anderson, S., Montelione, G. T., and Nilsson, B. (1996) J. Biomol. NMR 7, 131-141
20. Jansson, M., Uhlén, M., and Nilsson, B. (1997) Biochemistry 36, 4108-4117
21. Nilsson, B., Forsberg, G., and Hartmanis, M. (1991) Methods Enzymol. 198, 3-16
22. Forsberg, G., Palm, G., Ekebacke, A., Josephson, S., and Hartmanis, M. (1990) Biochem. J. 271, 357-363
23. Jansson, M., Hallen, D., Koho, H., Andersson, G., Berghard, L., Heidrich, J., Nyberg, E., Uhlén, M., Kördel, J., and Nilsson, B. (1997) J. Biol. Chem. 272, 8189-8197
24. Ausubel, F. M. (1995) Current Protocols In Molecular Biology, Chapter 8.5, Wiley Interscience, New York
25. Muhandiram, D. R., Farrow, N. A., Xu, G. Y., Smallcombe, S. H., and Kay, L. E. (1993) J. Magn. Reson. 102, 317-321
26. Santoro, J., and King, G. C. (1992) J. Magn. Reson. 97, 202-207
27. Kay, L. E., Ikura, M., Tschudin, R., and Bax, A. (1990) J. Magn. Reson. 89, 496-514
28. Wittekind, M., and Mueller, L. J. (1993) J. Magn. Reson. B 101, 201-205
29. Grzesiek, S., and Bax, A. (1992) J. Am. Chem. Soc. 114, 6291-6293
30. Kay, L. E., Xu, G.-Y., Singer, A. U., Muhandiram, D. R., and Forman-Kay, J. D. (1993) J. Magn. Reson. 101, 333-337
31. Logan, T. M., Olejniczak, E. T., Xu, X. R., and Fesik, S. W. (1992) FEBS Lett. 314, 413-418
32. Montelione, G. T., Lyons, B. A., Emerson, S. D., and Tashiro, M. (1992) J. Am. Chem. Soc. 114, 10974-10975
33. Pascal, S. M., Muhandiram, D. R., Yamazaki, T., Forman-Kay, J. D., and Kay, L. E. (1994) J. Magn. Reson. 103, 197-201
34. Delaglio, F., Grzesiek, S., Vuister, G. M., Zhu, G., Pfeifer, J., and Bax, A. (1995) J. Biomol. NMR 6, 277-293
35. Kraulis, P. J. (1989) J. Magn. Reson. 84, 627-63
36. Kraulis, P. J., Domaille, P. J., Campbell-Burk, S. L., Van Aken, T., and Laue, E. D. (1994) Biochemistry 33, 3515-3531
37. Löfå, S., and Johnsson, B. (1990) J. Chem. Soc. Chem. Commun. 21, 1526-1528
38. Yamazaki, T., Pascal, S. M., Singer, A. U., Forman-Kay, J. D., and Kay, L. E. (1995) J. Am. Chem. Soc. 117, 3556-3564
39. Omichinski, J. G., Clore, G. M., Schaad, O., Felsenfeld, G., Trainor, C., Appella, E., Stahl, S. J., and Gronenborn, A. M. (1993) Science 261, 438-446
40. Grzesiek, S., Stahl, S. J., Wingfield, P. T., and Bax, A. (1996) Biochemistry 35, 10256-10261
41. Craven, J. C., Whitehead, B., Jones, S. K. A., Thulin, E., Blackburn, M., and Waltho, J. P. (1996) Biochemistry 36, 10287-10299
42. McAlister, M. S. B., Mott, H. R., van der Merwe, P., Campbell, I. D., Davis, S. J., and Driscoll, P. C. (1996) Biochemistry 35, 5982-5991
43. Jansson, M., Dixelius, J., Uhlén, M., and Nilsson, B. O. (1997) FEBS Lett. 416, 259-264
44. Otting, G., Liepinsh, E., and Wüthrich, K. (1993) Biochemistry 32, 3571-3582
45. Pascal, S. M., Singer, A. U., Gish, G., Yamazaki, T., Shoelson, S. E., Pawson, T., Kay, L. E., and Forman-Kay, J. D. (1994) Cell 77, 461-472
46. Gargaro, A. R., Frenkiel, T. A., Nieto, P. M., Birdsall, B., Polshakov, V. I., Morgan, W. D., and Feeney, J. (1996) Eur. J. Biochem. 238, 435-439
47. Otting, G. (1993) Curr. Opin. Struct. Biol. 3, 760-768
48. Zhang, W., Gustafson, T. A., Rutter, W. J., and Johnson, J. D. (1994) J. Biol. Chem. 269, 10609-10613
49. Kraulis, P. J. (1991) J. Appl. Crystallogr. 24, 946-950
50. Abagyan, R. A., Totrov, M. M., and Kuznetsov, D. N. (1994) J. Comp. Chem. 15, 488-506