Total alanine-scanning mutagenesis of insulin-like growth factor I (IGF- I) identifies differential binding epitopes for IGFBP-1 and IGFBP-3

Biochemistry

Volumn 38, Issue 20, 1999, Pages 6386-6396

  Dubaquié, Yves ^a   Lowman, Henry B ^a  

^a GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; EPITOPE; SOMATOMEDIN C;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CELL DEATH; CELL DIFFERENTIATION; CELL PROLIFERATION; ENZYME LINKED IMMUNOSORBENT ASSAY; INSULIN LIKE ACTIVITY; MUTAGENESIS; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN FAMILY; RECEPTOR BINDING;

ALANINE; AMINO ACID SUBSTITUTION; BACTERIOPHAGE M13; BINDING SITES; BIOSENSING TECHNIQUES; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; INSULIN-LIKE GROWTH FACTOR I; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; SOLUBILITY;

EID: 0033580610     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi990089p     Document Type: Article

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