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Macromolecular Chemistry and Physics

Volumn 203, Issue 10-11, 2002, Pages 1650-1657

Interactions of ligands with macromolecules: Rational design of specific inhibitors of aspartic protease of HIV-1

(2) Frecer, Vladimir a,b Miertus, Stanislav a

a UNIDO (Italy)

b CANCER RESEARCH INSTITUTE (Slovakia)

Author keywords

Aspartic protease of HIV 1; Design of inhibitors; Molecular mechanics; Molecular modelling; Solvent effects

Indexed keywords

1,3 BIS(3 AMINOBENZYL) 4,7 DIBENZYL 2,3,4,5,6,7 HEXAHYDRO 5,6 DIHYDROXY 1H 1,3 DIAZEPIN 2 ONE; 4,7 DIBENZYL 2,3,4,5,6,7 HEXAHYDRO 5,6 DIHYDROXY 1,3 BIS[4 (HYDROXYMETHYL)BENZYL] 2H 1,3 DIAZEPIN 2 ONE; A 77003; AMPRENAVIR; ANTIRETROVIRUS AGENT; ASPARTIC PROTEINASE; ASPARTIC PROTEINASE INHIBITOR; INDINAVIR; KYNOSTATIN 272; LIGAND; LOPINAVIR; NELFINAVIR; PSEUDOPEPTIDE; RITONAVIR; SB 204144; SOLVENT; TIPRANAVIR; UNCLASSIFIED DRUG;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; DRUG DESIGN; ENERGY; ENZYME INHIBITION; ENZYME INHIBITOR INTERACTION; HUMAN IMMUNODEFICIENCY VIRUS 1; HYDROPHOBICITY; MACROMOLECULE; MOLECULAR MECHANICS; MOLECULAR MODEL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SOLVATION; VIRUS RESISTANCE;

EID: 0037194141 PISSN: 10221352 EISSN: None Source Type: Journal
DOI: 10.1002/1521-3935(200207)203:10/11<1650::AID-MACP1650>3.0.CO;2-E Document Type: Article

Times cited : (15)

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