An allelic series of mutations in Smad2 and Smad4 identified in a genotype-based screen of N-ethyl-N-nitrosourea-mutagenized mouse embryonic stem cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 24, 2002, Pages 15542-15547

  Vivian, Jay L ^a   Chen, Yijing ^a   Yee, Della ^a   Schneider, Elizabeth ^a   Magnuson, Terry ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ETHYLNITROSOUREA; SMAD2 PROTEIN; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ALLELISM; ANIMAL CELL; ARTICLE; CELL LINE; CRYOPRESERVATION; EMBRYO; GENE FUNCTION; GENE MUTATION; GENETIC ANALYSIS; GENETIC SCREENING; GENOTYPE; MOUSE; MUTAGENESIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STEM CELL;

ABNORMALITIES; ALLELES; AMINO ACID SUBSTITUTION; ANIMALS; BLASTOCYST; CHIMERA; CODON; CROSSES, GENETIC; DNA-BINDING PROTEINS; ETHYLNITROSOUREA; FETAL DEATH; FETAL HEART; GENES; GENES, DOMINANT; GENES, LETHAL; GENETIC SCREENING; GENOTYPE; MICE; MICE, INBRED C57BL; MUTAGENESIS; MUTATION; PERICARDIUM; POINT MUTATION; PROTEIN STRUCTURE, TERTIARY; RNA SPLICING; SEQUENCE DELETION; SMAD2 PROTEIN; SMAD4 PROTEIN; STEM CELLS; TRANS-ACTIVATORS;

ANIMALIA; CHEN; GENETTA;

EID: 0037180505     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.242474199     Document Type: Article

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