[11C]RN5: A new agent for the in vivo imaging of myocardial α1-adrenoceptors

European Journal of Pharmacology

Volumn 453, Issue 2-3, 2002, Pages 231-238

  Matarrese, Mario ^a   Moresco, Rosa M ^a   Romeo, Giuseppe ^b   Turolla, Elia A ^a   Simonelli, Pasquale ^a   Todde, Sergio ^a   Belloli, Sara ^a   Carpinelli, Assunta ^a   Magni, Fulvio ^a   Russo, Filippo ^b   Galli Kienle, Marzia ^a   Fazio, Ferruccio ^a  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

^b UNIVERSITY OF CATANIA   (Italy)

Author keywords

1 Adrenoceptor antagonist; 11C RN5; Biodistribution; PET (positron emission tomography)

Indexed keywords

3 [2 [4 (2 METHOXYPHENYL)PIPERAZIN 1 YL]ETHYL]PYRIMIDO[5,4 B]INDOLE 2,4 DIONE; ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; METHYL IODIDE; N,N DIMETHYLFORMAMIDE; POTASSIUM HYDROXIDE; PRAZOSIN; RADIOLIGAND; UNCLASSIFIED DRUG; 3 (2 (4 (2 (11C)METHOXYPHENYL)PIPERAZIN 1 YL)ETHYL)PYRIMIDO(5,4 B)INDOLE 2,4 DIONE; 3-(2-(4-(2-(11C)METHOXYPHENYL)PIPERAZIN-1-YL)ETHYL)PYRIMIDO(5,4-B)INDOLE-2,4-DIONE; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; CARBON; INDOLE DERIVATIVE; LIGAND; PYRIMIDINE DERIVATIVE; RADIOPHARMACEUTICAL AGENT;

ADRENAL GLAND; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; CLINICAL STUDY; CONTROLLED STUDY; DRUG BINDING; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG MEGADOSE; DRUG UPTAKE; HEART; HEART MUSCLE; IMAGING; IN VIVO STUDY; INHIBITION KINETICS; ISOTOPE LABELING; KIDNEY; LUNG; MEDICAL ASSESSMENT; METHYLATION; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RADIOACTIVITY; RADIOCHEMISTRY; RADIODIAGNOSIS; RAT; SPLEEN; SYNTHESIS; ANIMAL; BINDING SITE; COMPUTER ASSISTED EMISSION TOMOGRAPHY; MALE; METABOLISM; RAT STRAIN; TISSUE DISTRIBUTION;

ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; BINDING SITES; CARBON RADIOISOTOPES; INDOLES; ISOTOPE LABELING; LIGANDS; MALE; MYOCARDIUM; PYRIMIDINES; RADIOPHARMACEUTICALS; RATS; RATS, INBRED STRAINS; RECEPTORS, ADRENERGIC, ALPHA-1; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0037174652     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(02)02454-8     Document Type: Article

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