Novel, potent, semisynthetic antimalarial carba analogues of the first-generation 1,2,4-trioxane artemether

Journal of Medicinal Chemistry

Volumn 42, Issue 26, 1999, Pages 5487-5493

  O'Neill, Paul M ^a   Searle, Natalie L ^a   Kan, Ka Wing ^a   Storr, Richard C ^a   Maggs, James L ^a   Ward, Stephen A ^a   Raynes, Kaylene ^a   Park, B Kevin ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,4 TRIOXANE DERIVATIVE; 10BETA [2 (2 FLUOROBENZYLOXY)ETHYL]DEOXOARTEMISININ; ANTIMALARIAL AGENT; ARTEETHER; ARTEMETHER; DIHYDROARTEMISININ; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM;

ANIMALS; ANTIMALARIALS; ARTEMISININS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MASS SPECTROMETRY; MICE; PLASMODIUM FALCIPARUM; SESQUITERPENES; SPECTROPHOTOMETRY, INFRARED;

EID: 0033619978     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9903545     Document Type: Article

References (22)

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