Novel route to the synthesis of peptides containing 2-amino-1′-hydroxymethyl ketones and their application as cathepsin K inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 20, 2002, Pages 2887-2891

  Mendonca, Rohan V ^a   Venkatraman, Shankar ^a   Palmer, James T ^a  

^a CELERA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN K; CATHEPSIN K INHIBITOR; ENZYME INHIBITOR; KETONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; OSTEOCLAST; OSTEOLYSIS; OSTEOPOROSIS; STRUCTURE ACTIVITY RELATION;

CATHEPSINS; DRUG DESIGN; HUMANS; INDICATORS AND REAGENTS; KETONES; OSTEOCLASTS; OSTEOPOROSIS; PEPTIDES; PROTEASE INHIBITORS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037152428     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00611-X     Document Type: Article

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